Metal–carbon electrode optimization for efficient electrochemical regeneration of 1,4-NADH: a new approach for sustainable biochemical synthesis

Yang Zhou, LingLong Huang, Yuan Tao, ChangQing Luo, JianMiao Xu, ZhiQiang Liu and YuGuo Zheng

Green Chem., 2025, 27, 5782
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Catalytic reduction of NAD(P)+ to NAD(P)H

Shunichi Fukuzumi, Yong-Min Lee and Wonwoo Nam

Chem. Commun., 2025, 61, 3271
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A path to perpetual chemical synthesis via photocatalytic cofactor regeneration

Vanshika Jain and Pramod P. Pillai

Chem. Sci., 2025, 16, 11184
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Hydrogen-bond-assisted meta-nitrogen-doped graphyne enables real-time electrocatalytic NADH tracking in single cells

Jiale Wei, Jing Jiang, Chuqi Li, Guo Wang, Jiayao Wulan, Huan Yang, Fangxu Shen, Daixin Ye, Kai Li, Xianchan Li and Yuqing Lin

Chem. Sci., 2026, 17, 4312
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Multi-enzyme mimics – cracking the code of subcellular cascade reactions and their potential biological applications

Shafaq Sahar, Shichao Sun, Akif Zeb, Lulu Jin, Yong Gao, Liangfei Tian, Wei Wang, An-Wu Xu and Zhengwei Mao

Mater. Chem. Front., 2023, 7, 3037
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High yield regeneration of 1,4-NAD(P)H via selective adsorption-/desorption-mediated visible-light photocatalysis on a noble-metal-free catalyst

Zheng-Wu Wang, Xin Tan, Zheng-Hao Wu, Jun-Hao Chen, Yi-Zhou Zhu and He-Fang Wang

J. Mater. Chem. A, 2025, 13, 8726
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A mediator-free enzyme carbonaceous cathode for bioelectrocatalytic reduction of furfural to furfuryl alcohol

Shize Zheng, Chenxi Zhang, Peng Zhan, Xiangshi Liu, Houchao Shan, Yong Wang, Bin Wang, Peiyong Qin, Di Cai and Tianwei Tan

Green Chem., 2025, 27, 3733
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A Multifunctional Covalent Organic Framework Nanozyme for Promoting Ferroptotic Radiotherapy against Esophageal Cancer

Le-Le Zhou, Qun Guan, Wei Zhou, Jing-Lan Kan, Kai Teng, Man Hu and Yu-Bin Dong

ACS Nano, 2023, 17, 20445
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Liquid-Metal Catalytic Solution for Enhanced Spontaneous Proton Coupled Electron Transfer

Yifeng Hou, Fengyan Wang, Xie He, Guanwu Li, Shining Wu, Mengyang Cao, Chengyu Wei, Lu Huang and Yingpeng Wu

ACS Materials Lett., 2024, 6, 5266
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Synergy Between Metal and Molecular Catalysts for (Photo)electrocatalytic 1,4-NADH Regeneration

Fengyuan Liu, Wenwen Shi, Shujie Tian, Yiyang Zhou, Chengcheng Feng, Chunmei Ding and Can Li

J. Phys. Chem. C, 2024, 128, 5927
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Structured Electrodes Enable High‐Rate and Selective Electrochemical Nicotinamide Adenine Dinucleotide Regeneration for Biocatalysis

Jonas Wolf, Roman Goy, Jonathan Alan Medlock, Julian Tobias Kleinhaus, Kevinjeorjios Pellumbi, Leon Wickert, Daniel Siegmund and Ulf‐Peter Apfel

ChemSusChem, 2026, 19
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Thermochemical heterolytic hydrogenation catalysis proceeds through polarization-driven hydride transfer

Hai-Xu Wang and Yogesh Surendranath

Nat. Chem., 2026, 18, 43
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Integrating Interfacial Ligand Tailoring and Machine Learning for Heterogeneous H2-Driven Chemoenzymatic Synthesis

Luyao Ge, Heng Liang, Wei Lan, Maodi Wang, Xiaoming Zhang, Aiping Jia, Xiang-Kui Gu, Qihua Yang and Xiaobo Li

ACS Catal., 2026, 16, 694
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Electrochemical NADH Regeneration Mediated by Pyridine Amidate Iridium Complexes Interconverting 1,4- and 1,6-NADH

Caterina Trotta, Gabriel Menendez Rodriguez, Cristiano Zuccaccia and Alceo Macchioni

ACS Catal., 2024, 14, 10334
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Hydride Transfer-Based CO2 Reduction Catalysis: Navigating Metal Hydride to Organic Hydride in the Catalytic Loop

Joyanta Choudhury, Ritu Bhardwaj and Sanajit Kumar Mandal

Acc. Chem. Res., 2024, 57, 2859
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Electrochemical Hydrogenation of N‐Heterocycles and Related Substrates: A Mini‐Review

Esteban Garcia‐Torres and David E. Herbert

Electrochemical Science Adv, 2025, 5
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Harnessing hydrogen spillover: Biomimetic dual-site platinum-gold catalyst mimicking NAD+ -reducing hydrogenase

Panpan Zhao, Rui Li, Jianguo Zhao, Yuehan Zhang, Zhixuan Yu, He Zhang and Shaojun Dong

Nano Today, 2025, 65, 102852
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Organocatalytic Hydrogen Evolution Reaction by Diazaphospholenes

Kaini Xu, Yu-Shan Zhang, Bing Zhong, Long Zhang, Jin-Dong Yang and Sanzhong Luo

J. Am. Chem. Soc., 2024, 146, 25956
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Highly efficient sulfadoxine aptasensors: From polyaniline probe to potassium ferricyanide probe

Xiao-Zhen Feng, Yu-Qi Ge, Fang-Li Chen, Zhencheng Chen, Guo-Cheng Han and Heinz-Bernhard Kraatz

Electrochimica Acta, 2026, 548, 147884
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Bis-Imidazolium-Embedded Heterohelicene: A Regenerable NADP+ Cofactor Analogue for Electrocatalytic CO2 Reduction

Pirudhan Karak, Sanajit Kumar Mandal and Joyanta Choudhury

J. Am. Chem. Soc., 2023, 145, 7230
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A Coupled System of Ni3S2 and Rh Complex with Biomimetic Function for Electrocatalytic 1,4-NAD(P)H Regeneration

Shujie Tian, Guifa Long, Panwang Zhou, Fengyuan Liu, Xianwen Zhang, Chunmei Ding and Can Li

J. Am. Chem. Soc., 2024, 146, 15730
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High Selectivity Cofactor NADH Regeneration Organic Iridium Complexes Used for High-Efficiency Chem-Enzyme Cascade Catalytic Hydrogen Transfer

Li-Jun Zhao, Caimei Zhang, Shixin Zhang, Xiaoyi Lv, Jiayang Chen, Xun Sun, Huijuan Su, Toru Murayama and Caixia Qi

Inorg. Chem., 2023, 62, 17577
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Product Distribution of Steady–State and Pulsed Electrochemical Regeneration of 1,4‐NADH and Integration with Enzymatic Reaction

Mohammed Ali Saif Al‐Shaibani, Thaleia Sakoleva, Luka A. Živković, Harry P. Austin, Mark Dörr, Liane Hilfert, Edgar Haak, Uwe T. Bornscheuer and Tanja Vidaković‐Koch

ChemistryOpen, 2024, 13
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Revisiting the Reaction Mechanism of Electrochemical 1,4‐NADH Regeneration on Carbon Electrodes

Mohammed Ali Saif Al‐Shaibani, Saksham Verma, Luka A. Zivkovic and Tanja Vidakovic‐Koch

ChemCatChem, 2025, 17
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Highly Selective Electrocatalytic 1,4‐NADH Regeneration Based on Host–Guest Recognition Mediated by Cucurbit[8]uril on NiO

Hongxia Ning, Yizhou Wu, Chang Liu, Ziqi Zhao, Zeju Li, Jian Dai, Peili Zhang, Fei Li, Licheng Sun and Fusheng Li

Angew Chem Int Ed, 2025, 64
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Facet-Engineered Copper Electrocatalysts Enable Sustainable NADH Regeneration with High Efficiency

Shuo Sun, Yizhou Wu, Yunxuan Ding, Linqin Wang, Xing Cao and Licheng Sun

J. Am. Chem. Soc., 2025, 147, 16630
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Highly Selective Electrocatalytic 1,4‐NADH Regeneration Based on Host–Guest Recognition Mediated by Cucurbit[8]uril on NiO

Hongxia Ning, Yizhou Wu, Chang Liu, Ziqi Zhao, Zeju Li, Jian Dai, Peili Zhang, Fei Li, Licheng Sun and Fusheng Li

Angewandte Chemie, 2025, 137
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The current status and future of solar-driven efficient <?A3B2 pi6?>NAD(P)H cofactor regeneration technology

Yonglong Li, Yizhou Wu, Shuo Sun, Wenping Li and Licheng Sun

Chin. Sci. Bull., 2025
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Recent progress in photocatalytic NAD(P)H regeneration for photocatalytic-enzymatic-coupling system

Wei Lan, Maodi Wang, Huicong Dai and Qihua Yang

Front. Chem. Sci. Eng., 2024, 18
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Lignocellulosic biomass valorization via bio-photo/electro hybrid catalytic systems

Jiu Wang, Hamed Shirvani, Heng Zhao, Md Golam Kibria and Jinguang Hu

Biotechnology Advances, 2023, 66, 108157
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