Ulva lactuca polysaccharides combined with fecal microbiota transplantation ameliorated dextran sodium sulfate‐induced colitis in C57BL/6J mice

Zhengqi Liu, Menghui Wang, Yuanyuan Hu, Jinjin Li, Wei Gong, Xiaoming Guo, Shuang Song and Beiwei Zhu

J Sci Food Agric, 2025, 105, 422
DOI: 10.1002/jsfa.13839

Protective Effect of Artocarpus heterophyllus Lam. (Jackfruit) Polysaccharides on Liver Injury Induced by Cyclophosphamide in Mice

Ming Cheng, Yifan Zheng, Gang Wu, Lehe Tan, Fei Xu, Yanjun Zhang, Xiaoai Chen and Kexue Zhu

Nutrients, 2024, 16, 166
DOI: 10.3390/nu16010166

Anti-inflammatory effects of natural polysaccharides: molecular mechanisms and nanotherapeutic applications

Jihao Yang, Kai Xiong, Tengzhen Li, Morang Zhang, Zhangyun Li, Zhili Wen and Yuchuan Jiang

Front. Immunol., 2025, 16
DOI: 10.3389/fimmu.2025.1723346

Effects of chitosan and its oligosaccharide on gut microbiota and metabolites disturbed by excessive protein consumption in vivo and in vitro

Linlin Wang, Lilong Wang, Nan Wang, Chen Song, Chengrong Wen and Shuang Song

Food Bioscience, 2024, 57, 103555
DOI: 10.1016/j.fbio.2023.103555

Bidirectional regulation effect of rhubarb as laxative and astringent by metabolomics studies

Ping Zhou, Jing Zhang, Yudi Xu, Peng Zhang, Zhihao Zhang, Yongqing Xiao and Ying Liu

Journal of Ethnopharmacology, 2024, 320, 117348
DOI: 10.1016/j.jep.2023.117348

From structure to function: A comprehensive overview of polysaccharide roles and applications

Bo‐wen Xu, Sai‐sai Li, Wen‐li Ding, Cai Zhang, Mujeeb Ur Rehman, Muhammad Farooq Tareen, Li Wang and Shu‐cheng Huang

Food Frontiers, 2025, 6, 15
DOI: 10.1002/fft2.490

Ovotransferrin ameliorated intestinal barrier dysfunction in DSS-induced ulcerative colitis mice via inhibition of PI3K-Akt/MAPK signaling pathways and modulation of tissue metabolism

Donglei Zheng, Lulu Ma, Xiaojuan Xin, Ying Gao, Shijian Dong, Ying Huang, Jijun Wu, Jiaying Huo and Shugang Li

International Journal of Biological Macromolecules, 2025, 321, 146274
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Comparison of chemical composition, antioxidant and anticancer activity of different molecular weight fractions of fucoidan extract from Saccharina japonica

Lei Wang, Yongxuan Liu, Shousen Guo, Chen Zhao, Kunlun Li, Zhijie Qin and Qiulin Yue

3 Biotech, 2026, 16
DOI: 10.1007/s13205-026-04755-6

Characterization of low-molecular-weight fucoidan prepared by photocatalysis degradation and its regulation effect on metabolomics of LPS-stimulated macrophages

Lilong Wang, Linlin Wang, Jinhe Tian, Chunhong Yan, Chen Song, Shuangcai Xiao and Shuang Song

Food Bioscience, 2024, 61, 104619
DOI: 10.1016/j.fbio.2024.104619

Effect of fucoidan molecular weight on gut microbiota composition and anti-inflammatory activity after in vitro dynamic digestion and fermentation

Huadan Zhang, Zhukun Huang, Xuekai Xue, Xianliang Luo, Zebin Guo, Song Miao and Baodong Zheng

International Journal of Biological Macromolecules, 2025, 330, 147976
DOI: 10.1016/j.ijbiomac.2025.147976

Low-molecular-weight fucoidan prepared by ultrasonic/H2O2/VC degradation: Characterization, gut microbiota regulation, and anti-inflammatory effects

Huadan Zhang, Congcong Sun, Kailin Li, Xianliang Luo, Zebin Guo, Song Miao and Baodong Zheng

Food Bioscience, 2025, 72, 107532
DOI: 10.1016/j.fbio.2025.107532

Comparative immunomodulatory and gut microbiota-regulating effects of macroalgal polysaccharides in cyclophosphamide-induced immunosuppressed mice

Wei-Hao Huang, Pin-Yu Tsai, Chien-Li Chen and Chung-Hsiung Huang

International Immunopharmacology, 2026, 174, 116365
DOI: 10.1016/j.intimp.2026.116365

Glycyrrhiza uralensis Polysaccharide Modulates Characteristic Bacteria and Metabolites, Improving the Immune Function of Healthy Mice

Wangdi Song, Taifeng Zhang, Yunyun Wang, Shengnan Xue, Yan Zhang and Genlin Zhang

Nutrients, 2025, 17, 225
DOI: 10.3390/nu17020225

The gut microbiota intervenes in glucose tolerance and inflammation by regulating the biosynthesis of taurodeoxycholic acid and carnosine

Jianhua Zhen, Yunan Zhang, Yini Li, Yali Zhou, Yanan Cai, Guangrui Huang and Anlong Xu

Front. Cell. Infect. Microbiol., 2024, 14
DOI: 10.3389/fcimb.2024.1423662

Ecological and metabolic shifts of synthetic bacterial communities using sea cucumber sulfated polysaccharide as the sole carbon source

Zhengqi Liu, Yuanyuan Hu, Jinjin Li, Xiaoming Guo, Chunqing Ai, Shuang Song and Beiwei Zhu

Food Bioscience, 2024, 58, 103701
DOI: 10.1016/j.fbio.2024.103701

A mannose-rich exopolysaccharide-1 isolated from Bifidobacterium breve mitigates ovalbumin-induced intestinal damage in mice by modulation CD4 + T cell differentiation and inhibiting NF-κB signaling pathway

Meng-Meng Niu, Yan Li, Qian Su, Si-Yuan Chen, Qiao-Hui Li, Huan-Xin Guo, Xiang-Chen Meng and Fei Liu

International Journal of Biological Macromolecules, 2024, 280, 135850
DOI: 10.1016/j.ijbiomac.2024.135850

A sulfated polysaccharide from Laminaria japonica alleviated colitis via remodeling gut microbiota and promoting butyrate-mediated barrier repair

Yuxin Xiong, Huamai Qiu, Yifan Chen, Jiayu Yong, Abdul Mueed and Lijun You

International Journal of Biological Macromolecules, 2026, 354, 151462
DOI: 10.1016/j.ijbiomac.2026.151462

Structural characterization of a fucoidan from Ascophyllum nodosum and comparison of its protective effect against cellular oxidative stress with its analogues

Lilong Wang, Linlin Wang, Chunhong Yan, Yinghuan Fu, Jing-Feng Yang, Jiale Ma and Shuang Song

International Journal of Biological Macromolecules, 2023, 239, 124295
DOI: 10.1016/j.ijbiomac.2023.124295

Molecular mechanisms of ameliorating DSS-induced ulcerative colitis mediated by human milk oligosaccharide 2′-fucosyllactose based on RNA-seq analysis

Xianxiang Chen, Liuming Xie, Xiangwen Pan, Qiang Yu, Yi Chen, Mingyue Shen and Jianhua Xie

International Dairy Journal, 2025, 166, 106227
DOI: 10.1016/j.idairyj.2025.106227

Postbiotics of Naturally Fermented Synbiotic Mixture of Rice Water Aids in Promoting Colonocyte Health

Charumathi Anbalagan, Sangeetha Kadapakkam Nandabalan, Pavithra Sankar, Prasanna Srinivasan Rajaram, Karthick Govindaraj, Secunda Rupert and Jeswanth Sathyanesan

Biomolecules, 2024, 14, 344
DOI: 10.3390/biom14030344

A polysaccharide isolated from sea cucumber intestines enhances immunity and modulates gut microbiota and metabolism with efficacy comparable to that from the body wall

Xinyi Jin, Lin Bai, Chen Song, Jingjing Li, Xiaomeng Ren, Fanhua Kong, Chunqing Ai and Shuang Song

Food Bioscience, 2026, 75, 108084
DOI: 10.1016/j.fbio.2025.108084

Chitosan and its oligosaccharide accelerate colonic motility and reverse serum metabolites in rats after excessive protein consumption

Linlin Wang, Lilong Wang, Cui Cao, Jun Zhao, Chen Song, Zhijie Bao, Chunhong Yan and Shuang Song

International Journal of Biological Macromolecules, 2023, 253, 127072
DOI: 10.1016/j.ijbiomac.2023.127072

Seaweed-derived bioactives: Gut microbiota targeted interventions for immune function

Holly Sedgwick, Glenn Gibson, Jessica Adams and Anisha Wijeyesekera

Journal of Functional Foods, 2025, 125, 106696
DOI: 10.1016/j.jff.2025.106696

Bergamot polysaccharides relieve DSS-induced ulcerative colitis via regulating the gut microbiota and metabolites

Yiren Yang, Yuwei Zhang, Jiangping Song, Yaqian Li, Liuyang Zhou, Hongtao Xu, Kaizhang Wu, Jie Gao, Mouming Zhao and Yang Zheng

International Journal of Biological Macromolecules, 2023, 253, 127335
DOI: 10.1016/j.ijbiomac.2023.127335

Degradation of low-molecular-weight fucoidans by human intestinal microbiota and their regulation effect on intestinal microbiota and metabolites during in vitro fermentation

Xiaona Sun, Yunning Yang, Chen Song, Chunqing Ai, Jingfeng Yang and Shuang Song

Food Bioscience, 2024, 62, 105287
DOI: 10.1016/j.fbio.2024.105287