Fucoidan Treatment Improves Diabetic Hyperglycemia and Dyslipidemia in Rodents: A Systematic Review and Meta-Analysis

Kana Watanuki, Rin Akiyama, Shiita Watanabe, Eri Adachi and Masako Shimada

Nutrients, 2026, 18, 1155
DOI: 10.3390/nu18071155

Building Fucoidan/Agarose-Based Hydrogels as a Platform for the Development of Therapeutic Approaches against Diabetes

Lara L. Reys, Simone S. Silva, Diana Soares da Costa, Luísa C. Rodrigues, Rui L. Reis and Tiago H. Silva

Molecules, 2023, 28, 4523
DOI: 10.3390/molecules28114523

Fucoidan Alleviates Chemotherapy-Induced Peripheral Neuropathy via Activating the Gas6/MerTK Signaling Pathway to Reduce Neuroinflammation

Yunbo Yang, Xinyi Ma, Xinchu Ni, Shirong Ruan, Lanyue Tang, Zeyi Ju, Minghao Wang, Rumeng Jia, Yongyi Chen, Wen-Tao Liu and Liang Hu

J. Agric. Food Chem., 2025, 73, 31930
DOI: 10.1021/acs.jafc.5c09429

Polysaccharides from edible macroalgae: their extraction, purification, and therapeutic potentials in inflammation and oxidative stress-related diseases

Nazli Pinar Arslan, Ramazan Altun, Revda Topcu-Esim, Elanur Dasdemir, Muhammet Enes Kiziler, Fatih Kayar, Ekrem Darendelioglu, Fatma Altinok, Meryem Doymus and Mesut Taskin

Critical Reviews in Food Science and Nutrition, 2026, 1
DOI: 10.1080/10408398.2026.2643765

Anti-inflammatory effect of fucoidan isolated from fermented Sargassum fusiforme in in vitro and in vivo models

Lei Wang, Yong Ri Cui, Kaiqiang Wang, Xiaoting Fu, Jiachao Xu, Xin Gao and You-Jin Jeon

International Journal of Biological Macromolecules, 2022, 222, 2065
DOI: 10.1016/j.ijbiomac.2022.10.005

Health benefits of algae and marine-derived bioactive metabolites for modulating ulcerative colitis symptoms

Najmeh Oliyaei, Saghar Zekri, Aida Iraji, Alireza Oliyaei, Romina Tanideh, Nadiar M. Mussin, Amin Tamadon and Nader Tanideh

Journal of Functional Foods, 2025, 125, 106690
DOI: 10.1016/j.jff.2025.106690

A review on marine algae polysaccharides: From extraction, structural characteristics to anti-type 2 diabetes mellitus mechanisms and structure-activity relationship

Na Wang, Wendi Xu, Wenxi Duan, Jingyi Qin, Haibo Huang, Jingjing Liu, Lijuan Zhu and Wenzhou Xiang

Journal of Agriculture and Food Research, 2026, 26, 102653
DOI: 10.1016/j.jafr.2026.102653

Surfactin Mitigates a High-Fat Diet and Streptozotocin-Induced Type 2 Diabetes through Improving Pancreatic Dysfunction and Inhibiting Inflammatory Response

Xiaoyu Chen, Hongyuan Zhao, Yajun Lu, Huawei Liu, Fanqiang Meng, Zhaoxin Lu and Yingjian Lu

IJMS, 2022, 23, 11086
DOI: 10.3390/ijms231911086

Evaluation of the effects of fucoidan extracted from sargassum angustifolium on coagulation factors and biochemical parameters in male Wistar rats

Asma Dehghani, Ameneh Khoshvaghti and Narges Obeidi

Hematology, Transfusion and Cell Therapy, 2026, 48, 106073
DOI: 10.1016/j.htct.2025.106073

Fucoidan Improves Early Stage Diabetic Nephropathy via the Gut Microbiota–Mitochondria Axis in High-Fat Diet-Induced Diabetic Mice

Zhaoyi Zhong, Yangting Zhang, Yuan Wei, Xiaona Li, Lisheng Ren, Yan Li, Xueqian Zhang, Chengyu Chen, Xueru Yin, Run Liu and Qiuzhen Wang

J. Agric. Food Chem., 2024, 72, 9755
DOI: 10.1021/acs.jafc.3c08503

Research on the effects of different sugar substitutes—Mogroside V, Stevioside, Sucralose, and Erythritol—On glucose, lipid, and protein metabolism in type 2 diabetic mice

Huaxue Huang, Bin Wang, Zhi Peng, Sha Liu, Shuang Zhan, Xiulian Yang, Sirui Huang, Wei Wang, Yizhun Zhu and Wenjun Xiao

Food Research International, 2025, 209, 116262
DOI: 10.1016/j.foodres.2025.116262

Effect of fucoidan supplementation on glycolipid metabolism, systemic inflammation and gut microbiota in prediabetes: A randomized controlled trial

Yaping Liu, Ze Xu, Dongdong Zhang, Yujing Zhang, Wenjie Li, Wenyi Liu and Xing Li

International Journal of Biological Macromolecules, 2025, 287, 138415
DOI: 10.1016/j.ijbiomac.2024.138415

Tanshinone IIA ameliorates pancreatic injury in type 2 diabetic mice by modulating inflammation and endoplasmic reticulum stress via the IL-6/JAK2/STAT3 pathway

Yingfeng Li, Desheng Wang, Yuhang Liu, Chenyang Liu, Meixi Chen, Jingqi Li, Zunqiu Wu and Ning Wu

Funct Integr Genomics, 2025, 25
DOI: 10.1007/s10142-025-01718-7