Strategies to engineer articular cartilage with biomimetic zonal features: a review

Angela Semitela, Paula A. A. P. Marques and António Completo

Biomater. Sci., 2024, 12, 5961
DOI: 10.1039/D4BM00579A

Platelet-rich plasma-contained drug delivery systems to treat orthopedic injuries

Mingdong Liu, Jiaxin Ding, Yanbo Peng, Jialin Fang, Man Zhao, Wenyuan Zhang, Haotian Chen, Jian Zhang, Haisheng Peng and Qun Wang

International Journal of Pharmaceutics: X, 2025, 10, 100372
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Disease-Modifying Effects of Lenvatinib, a Multiple Receptor Tyrosine Kinase Inhibitor, on Posttraumatic Osteoarthritis of the Knee

Yasuyuki Sogo, Eriko Toyoda, Toshihiro Nagai, Takumi Takahashi, Daichi Takizawa, Masahiko Watanabe and Masato Sato

IJMS, 2024, 25, 6514
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Exosomes derived from platelet-rich plasma present a novel potential in repairing knee articular cartilage defect combined with cyclic peptide-modified β-TCP scaffold

Xuchang Liu, Rudong Chen, Guanzheng Cui, Rongjie Feng and Kechun Liu

J Orthop Surg Res, 2024, 19
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Optimal frequency of platelet-rich plasma injections for managing osteoarthritis: A longitudinal study

Masahiko Kemmochi

Regenerative Therapy, 2025, 29, 227
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Platelet-Rich Plasma in the Treatment of Musculoskeletal Disease in 2025 and Beyond

Benjamin B. Rothrauff, Joseph T. Featherall, Tyler J. Uppstrom, Greta Gohring, Anna-Laura Nelson, Thos A. Evans, Peter J. Millett, Matthew T. Provencher, Marc J. Philippon and Johnny Huard

Am J Sports Med, 2026
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Anti-Aging Potential of Platelet Rich Plasma (PRP): Evidence from Osteoarthritis (OA) and Applications in Senescence and Inflammaging

James Vun, Neelam Iqbal, Elena Jones and Payal Ganguly

Bioengineering, 2023, 10, 987
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Development of a super-hydrophilic anaerobic tube for the optimization of platelet-rich fibrin

Yan Wei, Yihong Cheng, Hongjiang Wei, Yulan Wang, Xiaoxin Zhang, Richard J. Miron, Yufeng Zhang and Shanglan Qing

Platelets, 2024, 35
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Effect of platelet-rich plasma on angiogenic and regenerative properties in patients with critical limb ischemia

Hamid Tanzadehpanah, Sima Nobari, Ava Jalalian Hoseini, Farzaneh Ghotbani, Mohsen Mehrabzadeh, Jamal Jalili shahri, Amirreza Alipour, Mohsen Sheykhhasan, Hamed Manoochehri, Susan Darroudi and Hanie Mahaki

Regenerative Therapy, 2025, 28, 517
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Application of Biomedical Microspheres in Wound Healing

Caihong Yang, Zhikun Zhang, Lu Gan, Lexiang Zhang, Lei Yang and Pan Wu

IJMS, 2023, 24, 7319
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Diethylaminoethyl dextran as a multifunctional polycationic system: From molecular design to therapeutic advancement

Raagul Seenivasan, Praveen Halagali, Jey Kumar Pachiyappan, Aniket Navale, Kuljeet Kaur, Parashuram Bugadannavar, Anitha Marimuthu, Pawan Ganesh Nayak and Vamshi Krishna Tippavajhala

Carbohydrate Polymer Technologies and Applications, 2026, 14, 101140
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Liquid platelet-rich fibrin produced via horizontal centrifugation decreases the inflammatory response and promotes chondrocyte regeneration in vitro

Huimin Li, Ting Xia, Hao Zeng, Yun Qiu, Yan Wei, Yihong Cheng, Yulan Wang, Xiaoxin Zhang, Jin Ke, Richard Miron and Qing He

Front. Bioeng. Biotechnol., 2023, 11
DOI: 10.3389/fbioe.2023.1301430

Impact of Vascular Endothelial Growth Factor Concentration on the Short-term Efficacy of Platelet-Rich Plasma (PRP) Therapy for Knee Osteoarthritis

Nanako Yamamoto, Yoshitomo Saita, Yohei Kobayashi, Takanori Wakayama, Sayuri Uchino, Yasumasa Momoi, Ryosuke Nakajima, Takaya Ohtaki, Haruka Kaneko and Muneaki Ishijima

CARTILAGE, 2025
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Microparticle Hydrogel Material Properties Emerge from Mixing-Induced Homogenization in a Poly(ethylene glycol) and Dextran Aqueous Two-Phase System

Thomas J. Tigner, Grant Scull, Ashley C. Brown and Daniel L. Alge

Macromolecules, 2023, 56, 8518
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Inflammatory responsive hydrogels incorporated with bevacizumab-loaded infinite coordination nanopolymers for accelerating cartilage repair

Haining Chen, Xin Tao, Jinbo Liu, Qian Kong, Li Wang, Yiwen Zhao, Chao Jiang, Yu Song, Xu Xu, Jialin Zhu, Yiyang Wang, Fengyi Du, Baoding Chen and Jun Wu

Journal of Colloid and Interface Science, 2025, 700, 138484
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Perspectives for using platelet-rich plasma in the treatment of knee osteoarthritis: Can it be improved through modifications of the protocol?

Mikhail S. Bozhokin, Svetlana A. Bozhkova, Julia V. Sopova, Elena I. Leonova, Maxim I. Shubniakov, Aleksandr A. Rubel and Mario Simental-Mendía

Chinese Journal of Traumatology, 2026, 29, 32
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Considering the Cellular Landscape in Marrow Stimulation Techniques for Cartilage Repair

Maddie Hasson, Lorenzo M. Fernandes, Hanna Solomon, Tristan Pepper, Nicholas L. Huffman, Saitheja A. Pucha, Jason T. Bariteau, Jarred M. Kaiser and Jay M. Patel

Cells Tissues Organs, 2024, 1
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Effects and action mechanisms of individual cytokines contained in PRP on osteoarthritis

Zhengchao Wang, Pengfei Zhu, Bokai Liao, Hongbo You and Yu Cai

J Orthop Surg Res, 2023, 18
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Bevacizumab suppressed degenerative changes in articular cartilage explants from patients with osteoarthritis of the knee

Masaichi Sotozawa, Ken Kumagai, Kimi Ishikawa, Shunsuke Yamada, Yusuke Inoue and Yutaka Inaba

J Orthop Surg Res, 2023, 18
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Treatment of Chronic Haemophilic Synovitis with PRP: Clinical and In Vitro Studies

Horacio Caviglia, María Eulalia Landro, Paula Oneto, Guillermo Cambiaggi, Gustavo Galatro, Micaela Berni, Laura Caliogna, Eugenio Antonio Carrera Silva and Gianluigi Pasta

IJMS, 2024, 25, 9140
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Mechanisms and applications of the regenerative capacity of platelets-based therapy in knee osteoarthritis

Jiang-Yin Zhang, Xiao-Na Xiang, Xi Yu, Yan Liu, Hong-Ying Jiang, Jia-Lei Peng, Cheng-Qi He and Hong-Chen He

Biomedicine & Pharmacotherapy, 2024, 178, 117226
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Systematic Review of Platelet-Rich Plasma in Medical and Surgical Specialties: Quality, Evaluation, Evidence, and Enforcement

Eqram Rahman, Parinitha Rao, Hany Niamey Abu-Farsakh, Chirag Thonse, Imran Ali, Alice E. Upton, Shwetha Y. Baratikkae, Jean D. A. Carruthers, Ash Mosahebi, Nima Heidari and William Richard Webb

JCM, 2024, 13, 4571
DOI: 10.3390/jcm13154571

VEGF-neutralized platelet-rich plasma with adipose-derived stromal vascular fraction enhanced osteochondral repair in a point-of-care goat model

Shinsuke Kihara, Benjamin B. Rothrauff, Tomoya Iseki, Kalon J. Overholt, Yijen L. Wu, Hang Lin, Peter G. Alexander and Rocky S. Tuan

Journal of Orthopaedic Translation, 2026, 56, 101034
DOI: 10.1016/j.jot.2025.101034

Platelet Rich Plasma in the Repair of Articular Cartilage Injury: A Narrative Review

Yinru Liang, Juan Li, Yuhui Wang, Junchu He, Liji Chen, Jiaqi Chu and Hongfu Wu

CARTILAGE, 2022, 13, 194760352211184
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