Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook

Haidong Li, Heejeong Kim, Feng Xu, Jingjing Han, Qichao Yao, Jingyun Wang, Kanyi Pu, Xiaojun Peng and Juyoung Yoon

Chem. Soc. Rev., 2022, 51, 1795
DOI: 10.1039/D1CS00307K

A biotin-guided near-infrared fluorescent probe for imaging hydrogen sulfide and differentiating cancer cells

Xuekang Cai, Zhuochen Zhang, Yalun Dong, Tingting Hao, Long Yi and Xing Yang

Org. Biomol. Chem., 2023, 21, 332
DOI: 10.1039/D2OB02034C

Enzyme-activatable fluorescent probes for β-galactosidase: from design to biological applications

Yongkang Yao, Yutao Zhang, Chenxu Yan, Wei-Hong Zhu and Zhiqian Guo

Chem. Sci., 2021, 12, 9885
DOI: 10.1039/D1SC02069B

Activatable fluorescence sensors forin vivobio-detection in the second near-infrared window

Mengyao Zhao, Benhao Li, Hongxin Zhang and Fan Zhang

Chem. Sci., 2021, 12, 3448
DOI: 10.1039/D0SC04789A

Near-infrared electroluminescence beyond 940 nm in Pt(N^C^N)X complexes: influencing aggregation with the ancillary ligand X

Rebecca J. Salthouse, Piotr Pander, Dmitry S. Yufit, Fernando B. Dias and J. A. Gareth Williams

Chem. Sci., 2022, 13, 13600
DOI: 10.1039/D2SC05023D

Excimer or aggregate? Near infrared electro- and photoluminescence from multimolecular excited states of N^C^N-coordinated platinum(ii) complexes

Piotr Pander, Amit Sil, Rebecca J. Salthouse, Christopher W. Harris, Melissa T. Walden, Dmitry S. Yufit, J. A. Gareth Williams and Fernando B. Dias

J. Mater. Chem. C, 2022, 10, 15084
DOI: 10.1039/D2TC01511K

Two-photon fluorescence imaging of the cerebral peroxynitrite stress in Alzheimer's disease

Xilei Xie, Yawen Liu, Guangzhao Liu, Yuying Zhao, Jinyan Liu, Yong Li, Jian Zhang, Xiaoyun Jiao, Xu Wang and Bo Tang

Chem. Commun., 2022, 58, 6300
DOI: 10.1039/D2CC01744J

Near-infrared fluorescent probes: a next-generation tool for protein-labeling applications

Shahi Imam Reja, Masafumi Minoshima, Yuichiro Hori and Kazuya Kikuchi

Chem. Sci., 2021, 12, 3437
DOI: 10.1039/D0SC04792A

Reaction-based fluorescent and chemiluminescent probes for formaldehyde detection and imaging

Shumei Huang, Zejun Li, Minghui Liu, Mengjiao Zhou, Jintao Weng, Yong He, Yin Jiang, Huatang Zhang and Hongyan Sun

Chem. Commun., 2022, 58, 1442
DOI: 10.1039/D1CC05644A

A chalcone-based fluorescent responsive probe for selective detection of nitroreductase activity in bacteria

Sirilak Wangngae, Thitima Pewklang, Kantapat Chansaenpak, Phongsakorn Ganta, Suphanida Worakaensai, Kittipan Siwawannapong, Surayut Kluaiphanngam, Nawarat Nantapong, Rung-Yi Lai and Anyanee Kamkaew

New J. Chem., 2021, 45, 11566
DOI: 10.1039/D1NJ01794B

A silicon rhodamine 1,2-dioxetane chemiluminophore for in vivo near-infrared imaging

Rokia Osman, Uroob Haris, Maidileyvis C. Cabello, Ralph P. Mason and Alexander R. Lippert

Org. Biomol. Chem., 2025, 23, 1846
DOI: 10.1039/D4OB02002B

Recent advances in highly-efficient near infrared OLED emitters

Paloma L. dos Santos, Patrycja Stachelek, Youhei Takeda and Piotr Pander

Mater. Chem. Front., 2024, 8, 1731
DOI: 10.1039/D3QM01067H

A colorimetric and near-infrared fluorescent probe with large Stokes shift for biothiol bioimaging

Mingli Xie, Tianxin Yang, Min Chen, Lu Yu, Tenghui Wang, Huihui Wei, Junhui Liu, Qinhong Jiang and Panfei Xing

New J. Chem., 2025, 49, 13958
DOI: 10.1039/D5NJ01958C

Development of Near-Infrared Nucleic Acid Mimics of Fluorescent Proteins for In Vivo Imaging of Viral RNA with Turn-On Fluorescence

Jiaheng Zhang, Huiyi Li, Bin Lin, Xingyu Luo, Peng Yin, Ting Yi, Binbin Xue, Xiao-Lian Zhang, Haizhen Zhu and Zhou Nie

J. Am. Chem. Soc., 2021, 143, 19317
DOI: 10.1021/jacs.1c04577

Lights on 2,5-diaryl tetrazoles: applications and limits of a versatile photoclick reaction

Valentina Pirota, Alessandra Benassi and Filippo Doria

Photochem Photobiol Sci, 2022, 21, 879
DOI: 10.1007/s43630-022-00173-8

Tuning asymmetric electronic structure endows carbon dots with unexpected huge stokes shift for high contrast in vivo imaging

Jingyu Hu, Yifei Guo, Xin Geng, Junli Wang, Sen Li, Yuanqiang Sun, Lingbo Qu and Zhaohui Li

Chemical Engineering Journal, 2022, 446, 136928
DOI: 10.1016/j.cej.2022.136928

Hypochlorite Detection by Fluorescent Sensors Bearing Long Alkyl Chains: The Role of Chain Length in Sensing Properties

Yuan Yang, Zhao Li, Fenghao Dong, Jiawei Lv, Bingyang Han, Yuqing Sun, Huiming Lu, Ziqiang Lei and Hengchang Ma

ChemPlusChem, 2022, 87
DOI: 10.1002/cplu.202200307

Design and development of a bright NIR fluorescent probe for selective HSA detection in human blood serum and urine

Arindam Mondal and Subrata Dutta

Bioorganic Chemistry, 2025, 159, 108356
DOI: 10.1016/j.bioorg.2025.108356

Xanthene‐Based Nitric Oxide‐Responsive Nanosensor for Photoacoustic Imaging in the SWIR Window

Chathuranga S. L. Rathnamalala, Selena Hernandez, Melissa Y. Lucero, Chelsea B. Swartchick, Abdul Kalam Shaik, Nathan I. Hammer, Amanda K. East, Steven R. Gwaltney, Jefferson Chan and Colleen N. Scott

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202214855

Electronic-Symmetry-Tuned Emission Beyond 1500 nm in Erbium(III)-Phthalocyanine Complexes for High-Resolution In Vivo Biosensing

Bin Wu, Lu Zhang, Kui Yan, Mei Mei, Wenxiao Wu, Zuyang He, Shangfeng Wang and Fan Zhang

J. Am. Chem. Soc., 2025, 147, 44185
DOI: 10.1021/jacs.5c13688

Bioconjugation of a Near-Infrared DNA-Stabilized Silver Nanocluster to Peptides and Human Insulin by Copper-Free Click Chemistry

Vanessa Rück, Narendra K. Mishra, Kasper K. Sørensen, Mikkel B. Liisberg, Ane B. Sloth, Cecilia Cerretani, Christian B. Mollerup, Andreas Kjaer, Chenguang Lou, Knud J. Jensen and Tom Vosch

J. Am. Chem. Soc., 2023, 145, 16771
DOI: 10.1021/jacs.3c04768

A caged luciferin analogue generating near-infrared bioluminescence for activity-sensing of labile iron

Yi Li, Fangliang Guo, Ruiyang Suo, Xinze Wu, Shiqi Jin, Jun Zhou, Caiju Zhang, Shuqi Li, Wang Qian, Huan ling, Shiwen Huang, Huaixia Chen and Bo Wu

Biosensors and Bioelectronics, 2025, 278, 117290
DOI: 10.1016/j.bios.2025.117290

Oxygen‐Sensing Chemiluminescent Iridium(III) 1,2‐Dioxetanes: Unusual Coordination and Activity

Husain N. Kagalwala, Lorena Bueno, Hashini Wanniarachchi, Daniel K. Unruh, Khagendra B. Hamal, Cyprian I. Pavlich, Graham J. Carlson, Kevin G. Pinney, Ralph P. Mason and Alexander R. Lippert

Analysis & Sensing, 2023, 3
DOI: 10.1002/anse.202200085

Microsolvation-Driven Hours-Long Spectral Dynamics in Phenoxazine Dyes

Ritu Kumari, Vineeta Chaturvedi, Mudit Pithi and Avik K. Pati

J. Phys. Chem. A, 2025, 129, 82
DOI: 10.1021/acs.jpca.4c06314

Initial immune response to a FRET-based MMP sensor-immobilized silk fibroin hydrogel in vivo

Yusuke Kambe and Tetsuji Yamaoka

Acta Biomaterialia, 2021, 130, 199
DOI: 10.1016/j.actbio.2021.05.030

Novel NIR-II 3,5-Julolidinyl aza-BODIPY for Photothermal Therapy of Gliomas Stem Cells by Brain Stereotactic Injection

Lulu Cao, Zhiqiang Cui, Dongxiang Zhang, Yikun Li, Xiaoyan Gao, Rong Shang, Xin-Dong Jiang, Jianjun Du and Xiaohong Sun

ACS Materials Lett., 2024, 6, 4765
DOI: 10.1021/acsmaterialslett.4c01447

Antinode-centre near-infrared tandem OLEDs enabled by ultrathin emissive layers

Min Song, Zheng Ren, Sheng-Fu Wang, Xiao-Bo Shi, Wei-Zhi Liu, Zi-Qi Feng, Dong-Ying Zhou, Pi-Tai Chou and Liang-Sheng Liao

Chemical Engineering Journal, 2025, 522, 167897
DOI: 10.1016/j.cej.2025.167897

Accelerated Activity-Based Sensing by Fluorogenic Reporter Engineering Enables to Rapidly Determine Unstable Analyte

Jingjing Li, Xizi Yu, Dunji Shu, Huihong Liu, Maoxin Gu, Kai Zhang, Guojiang Mao, Sheng Yang and Ronghua Yang

Anal. Chem., 2024, 96, 7723
DOI: 10.1021/acs.analchem.4c00945

Near-Infrared Fluorescent Probes for the Detection of Cancer-Associated Proteases

Jamie I. Scott, Qinyi Deng and Marc Vendrell

ACS Chem. Biol., 2021, 16, 1304
DOI: 10.1021/acschembio.1c00223

Biomimetic Approach to Promote Cellular Uptake and Enhance Photoacoustic Properties of Tumor-Seeking Dyes

Amanda K. East, Michael C. Lee, Chang Jiang, Qasim Sikander and Jefferson Chan

J. Am. Chem. Soc., 2023, 145, 7313
DOI: 10.1021/jacs.2c13489

Xanthene‐Based Dyes for Photoacoustic Imaging and their Use as Analyte‐Responsive Probes

Frederik Brøndsted and Cliff I. Stains

Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202400598

A near-infrared fluorescent probe for ratiometric imaging peroxynitrite in Parkinson's disease model

Hao Kang, Wei Shu, Jin Yu, Mengxu Gao, Rubing Han, Jing Jing, Rubo Zhang and Xiaoling Zhang

Sensors and Actuators B: Chemical, 2022, 359, 131393
DOI: 10.1016/j.snb.2022.131393

Engineering high-performance dicyanomethylene-4H-pyran fluorophores for biosensing and phototherapy

Qiang Liu, Chuyang Sun, Ruilong Dai, Chenxu Yan, Yutao Zhang, Wei-Hong Zhu and Zhiqian Guo

Coordination Chemistry Reviews, 2024, 503, 215652
DOI: 10.1016/j.ccr.2023.215652

Possibilities on the application of vibrational spectroscopy and data analytics in precision nutrition

Ni Dongdong and Daniel Cozzolino

TrAC Trends in Analytical Chemistry, 2023, 163, 117067
DOI: 10.1016/j.trac.2023.117067

Activatable Porphyrin-Based Sensors, Photosensitizers and Combination Therapeutics

Suritra Bandyopadhyay, Joseph A Forzano, Musa Dirak and Jefferson Chan

JACS Au, 2025, 5, 42
DOI: 10.1021/jacsau.4c01108

Repurposing Cyanine Photoinstability To Develop Near-Infrared Light-Activatable Nanogels for In Vivo Cargo Delivery

Rodrigo Tapia Hernandez, Michael C. Lee, Anuj K. Yadav and Jefferson Chan

J. Am. Chem. Soc., 2022, 144, 18101
DOI: 10.1021/jacs.2c08187

Covalent Probes for Aggregated Protein Imaging via Michael Addition

Wang Wan, Yanan Huang, Qiuxuan Xia, Yulong Bai, Yuwen Chen, Wenhan Jin, Mengdie Wang, Di Shen, Haochen Lyu, Yuqi Tang, Xuepeng Dong, Zhenming Gao, Qun Zhao, Lihua Zhang and Yu Liu

Angewandte Chemie, 2021, 133, 11436
DOI: 10.1002/ange.202015988

Xanthene‐Based Nitric Oxide‐Responsive Nanosensor for Photoacoustic Imaging in the SWIR Window

Chathuranga S. L. Rathnamalala, Selena Hernandez, Melissa Y. Lucero, Chelsea B. Swartchick, Abdul Kalam Shaik, Nathan I. Hammer, Amanda K. East, Steven R. Gwaltney, Jefferson Chan and Colleen N. Scott

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202214855

Recent advances in nanotechnology for simultaneous detection of multiple pathogenic bacteria

Yizhong Shen, Yiyin Zhang, Zhong Feng Gao, Yingwang Ye, Qingping Wu, Hong-Yuan Chen and Jing-Juan Xu

Nano Today, 2021, 38, 101121
DOI: 10.1016/j.nantod.2021.101121

Photoacoustic/fluorescence dual-modality cyanine-based probe for real-time imaging of endogenous cysteine and in situ diagnosis of cervical cancer in vivo

Xiang Zou, Yuping Zhao and Weiying Lin

Analytica Chimica Acta, 2023, 1239, 340713
DOI: 10.1016/j.aca.2022.340713

Activity‐based Photoacoustic Probes Reveal Elevated Intestinal MGL and FAAH Activity in a Murine Model of Obesity

Melissa Y. Lucero, Sarah H. Gardner, Anuj K. Yadav, Austin Borri, Zhenxiang Zhao and Jefferson Chan

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202211774

Chemiluminescent 1,2‐Dioxetane Iridium Complexes for Near‐Infrared Oxygen Sensing

Husain N. Kagalwala, Jeni Gerberich, Chancellor J. Smith, Ralph P. Mason and Alexander R. Lippert

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202115704

Activity-Based NIR Bioluminescence Probe Enables Discovery of Diet-Induced Modulation of the Tumor Microenvironment via Nitric Oxide

Anuj K. Yadav, Michael C. Lee, Melissa Y. Lucero, Shengzhang Su, Christopher J. Reinhardt and Jefferson Chan

ACS Cent. Sci., 2022, 8, 461
DOI: 10.1021/acscentsci.1c00317

Activity-Based Nitric Oxide-Responsive Porphyrin for Site-Selective and Nascent Cancer Ablation

Suritra Bandyopadhyay, Zhenxiang Zhao, Amanda K. East, Rodrigo Tapia Hernandez, Joseph A. Forzano, Benjamin A. Shapiro, Anuj K. Yadav, Chelsea B. Swartchick and Jefferson Chan

ACS Appl. Mater. Interfaces, 2024, 16, 9680
DOI: 10.1021/acsami.3c15604

Covalent Probes for Aggregated Protein Imaging via Michael Addition

Wang Wan, Yanan Huang, Qiuxuan Xia, Yulong Bai, Yuwen Chen, Wenhan Jin, Mengdie Wang, Di Shen, Haochen Lyu, Yuqi Tang, Xuepeng Dong, Zhenming Gao, Qun Zhao, Lihua Zhang and Yu Liu

Angew Chem Int Ed, 2021, 60, 11335
DOI: 10.1002/anie.202015988

Activity-based photoacoustic probe for biopsy-free assessment of copper in murine models of Wilson’s disease and liver metastasis

Melissa Y. Lucero, Yuqi Tang, Chloe J. Zhang, Shengzhang Su, Joseph A. Forzano, Valeria Garcia, Xin Huang, David Moreno and Jefferson Chan

Proc. Natl. Acad. Sci. U.S.A., 2021, 118
DOI: 10.1073/pnas.2106943118

Coumarin-based near-infrared fluorogenic probes: Recent advances, challenges and future perspectives

Yufan Fan, Yue Wu, Jie Hou, Ping Wang, Xiaojun Peng and Guangbo Ge

Coordination Chemistry Reviews, 2023, 480, 215020
DOI: 10.1016/j.ccr.2023.215020

Development of NIR-II Photoacoustic Probes Tailored for Deep-Tissue Sensing of Nitric Oxide

Melissa Y. Lucero, Amanda K. East, Christopher J. Reinhardt, Adam C. Sedgwick, Shengzhang Su, Michael C. Lee and Jefferson Chan

J. Am. Chem. Soc., 2021, 143, 7196
DOI: 10.1021/jacs.1c03004

A preliminary study on the utilisation of near infrared spectroscopy to predict age and in vivo human metabolism

Dongdong Ni, Heather E. Smyth, Michael J. Gidley and Daniel Cozzolino

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 265, 120312
DOI: 10.1016/j.saa.2021.120312

Fidelity-oriented fluorescence imaging probes for beta-galactosidase: From accurate diagnosis to precise treatment

Bin Feng, Feiyi Chu, Anyao Bi, Xueyan Huang, Yanpeng Fang, Meihui Liu, Fei Chen, Yanbing Li and Wenbin Zeng

Biotechnology Advances, 2023, 68, 108244
DOI: 10.1016/j.biotechadv.2023.108244

Seeing the unseen: NIR probes for reactive nitrogen species biosensing and bioimaging

Meihui Liu, Yiyang Zhou, Ting Luo, Xiaozheng Cao, Duoyang Fan, Shuai Huang, Jie Dong, Fei Chen and Wenbin Zeng

Talanta, 2025, 285, 127334
DOI: 10.1016/j.talanta.2024.127334

Deep NIR-I Emissive Iridium(III) Complex Bearing D-A Ligand: Synthesis, Photophysical Properties and DFT/TDDFT Calculation

Jia-Yang Jiang, Zi-Han Xu, Tang Li, Da-Hua Cai, Hui Zhou and Ze-Jing Chen

Crystals, 2021, 11, 1038
DOI: 10.3390/cryst11091038

A FRET-Based Ratiometric H 2 S Sensor for Sensitive Optical Molecular Imaging in Second Near-Infrared Window

Shan Lei, Kejia Jiang, Chenqing Zhang, Wei Sun, Yuantao Pan, Dong Wang, Peng Huang and Jing Lin

Research, 2023, 6
DOI: 10.34133/research.0286

Revisiting the Chemistry and Photophysics of 3‐(N‐Methylpyridinium‐4‐yl)Coumarins for Designing “Covalent‐Assembly” and “Molecular Disassembly” Fluorescent Probes**

Vincent Gaumerd, Kévin Renault, Pierre‐Yves Renard and Anthony Romieu

ChemPhotoChem, 2024, 8
DOI: 10.1002/cptc.202300324

Near-Infrared Luminescence from Transparent Thin Films of Copper(I) Thiocyanate Modified with 2-Mercaptobenzothiazole via Excited-State Symmetry Breaking

Saran Waiprasoet, Paul A. Hume, James M. Scott, Phattananawee Nalaoh, Pongkamon Prayongkul, Daniel M. Packwood, Justin M. Hodgkiss, David J. Harding and Pichaya Pattanasattayavong

Inorg. Chem., 2026
DOI: 10.1021/acs.inorgchem.5c05480

Developments in near-infrared fluorescent probes for G-quadruplexes structures

Jiaona Han, Jun Li, Xingyu Luo, Guangfu Feng and Jiaheng Zhang

Coordination Chemistry Reviews, 2024, 520, 216157
DOI: 10.1016/j.ccr.2024.216157

NIR‐Activatable, Sequence‐Specific Metal‐Nucleic Acid Scaffolds for Responsive Uncaging

Arpit Sharma, Man Kshetri, Deepak Karna, Md Al Amin, Shirin Akter, Hanbin Mao and Yao‐Rong Zheng

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202514717

NIR imaging human telomeric dimeric G-quadruplexes by malachite green dimers and their antitumor activity

Fei Lu, Meng-Jia Zhang, Jun-Hui Li, Pei-Dan You, Lihong Liu and Chun-Qiong Zhou

Dyes and Pigments, 2022, 203, 110307
DOI: 10.1016/j.dyepig.2022.110307

Single-Molecule Detection of DNA-Stabilized Silver Nanoclusters Emitting at the NIR I/II Border

Mikkel B. Liisberg, Zahra Shakeri Kardar, Stacy M. Copp, Cecilia Cerretani and Tom Vosch

J. Phys. Chem. Lett., 2021, 12, 1150
DOI: 10.1021/acs.jpclett.0c03688

Microparticle-Based Biochemical Sensing Using Optical Coherence Tomography and Deep Learning

Shreyas Shah, Chun-Nam Yu, Mingde Zheng, Heejong Kim and Michael S. Eggleston

ACS Nano, 2021, 15, 9764
DOI: 10.1021/acsnano.1c00497

Development of novel near-infrared GFP chromophore-based fluorescent probes for imaging of amyloid-β plaque and viscosity

Yuhui Guo, Huaxiang Leng, Qingxiu Chen, Junyi Su, Wen-jing Shi, Chunli Xia, Lei Zhang and Jinwu Yan

Sensors and Actuators B: Chemical, 2022, 372, 132648
DOI: 10.1016/j.snb.2022.132648

Near‐Infrared‐Light‐Driven Photochemistry and Photocatalysis: Mechanisms, Recent Applications, and Opportunities in Organic Synthesis and Biology

Santosh K. Pagire, Wesley J. Olivier, Debabrata Maiti and Alex C. Bissember

Angew Chem Int Ed, 2026
DOI: 10.1002/anie.202526147

Rationally Engineered hCES2A Near-Infrared Fluorogenic Substrate for Functional Imaging and High-Throughput Inhibitor Screening

Yufan Fan, Tiantian Zhang, Yunqing Song, Zhipei Sang, Hairong Zeng, Peiqi Liu, Ping Wang and Guangbo Ge

Anal. Chem., 2023, 95, 15665
DOI: 10.1021/acs.analchem.3c02873

Fluorogenic Probes for Functional Imaging of Endoplasmic Reticulum‐Resident Proteins: from Molecular Engineering to Biomedical Applications

Yufan Fan, Feng Zhang, Yumeng Hao, Lin Chen, Qihang Zhou, Hairong Zeng, Yunqing Song, Zhaobin Guo, Xiaojun Peng and Guangbo Ge

Adv Funct Materials, 2025, 35
DOI: 10.1002/adfm.202416057

Hydrolysis-Resistant Ester-Based Linkers for Development of Activity-Based NIR Bioluminescence Probes

Anuj K Yadav, Zhenxiang Zhao, Yourong Weng, Sarah H Gardner, Catharine J Brady, Oliver D Pichardo Peguero and Jefferson Chan

J. Am. Chem. Soc., 2023, 145, 1460
DOI: 10.1021/jacs.2c12984

Multiple GSH-depleting dimeric cyanine for photothermal-ferroptosis induction with NIR-II fluorescence visualization and renal clearance

Yuantao Pan, Shan Lei, Qiang Liu, Kaiwei Chen, Yu Zhang, Meng Li, Yurong Liu, Mengwei Bai, Huishan Guo, Peng Huang and Jing Lin

Cell Reports Physical Science, 2026, 7, 103027
DOI: 10.1016/j.xcrp.2025.103027

Near‐Infrared‐Light‐Driven Photochemistry and Photocatalysis: Mechanisms, Recent Applications, and Opportunities in Organic Synthesis and Biology

Santosh K. Pagire, Wesley J. Olivier, Debabrata Maiti and Alex C. Bissember

Angewandte Chemie, 2026
DOI: 10.1002/ange.202526147

Synthesis of Silicon-Substituted Hemicyanines for Multimodal SWIR Imaging

Amanda K. East, Michael C. Lee, Lukas P. Smaga, Chang Jiang, Sharath C. Mallojjala, Jennifer S. Hirschi and Jefferson Chan

Org. Lett., 2022, 24, 8509
DOI: 10.1021/acs.orglett.2c03382

Red/near-infrared (NIR) difluoroboron β-diketonate derivatives with reversible mechanochromism for cellular imaging

Yunpeng Qi, Wei Liu, Tao Du, Junlong Wang and Songlin Jiao

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 325, 124986
DOI: 10.1016/j.saa.2024.124986

A near-infrared turn-on fluorescent sensor for the determination of copper in mitochondria

Taiyu Guo, Ruowei Tian, Wangbo Qu, Bin Yang, Zhirong Geng and Zhilin Wang

Dyes and Pigments, 2022, 205, 110483
DOI: 10.1016/j.dyepig.2022.110483

Activity-Based Photoacoustic Probes for Detection of Disease Biomarkers beyond Oncology

Michael C. Lee, Kayla Landers and Jefferson Chan

ACS Bio Med Chem Au, 2023, 3, 223
DOI: 10.1021/acsbiomedchemau.3c00009

Activity-based fluorescence probes for pathophysiological peroxynitrite fluxes

Zhiqiang Mao, Jianhua Xiong, Pengzhan Wang, Jusung An, Fan Zhang, Zhihong Liu and Jong Seung Kim

Coordination Chemistry Reviews, 2022, 454, 214356
DOI: 10.1016/j.ccr.2021.214356

Sensing Reactive Oxygen Species with Photoacoustic Imaging Using Conjugation-Extended BODIPYs

Jean Michél Merkes, Alexa Hasenbach, Fabian Kiessling, Sven Hermann and Srinivas Banala

ACS Sens., 2021, 6, 4379
DOI: 10.1021/acssensors.1c01674

Effects of parabolic barrier design for multiple GaAsBi/AlGaAs quantum well structures

Monika Jokubauskaitė, Gustas Petrusevičius, Aivaras Špokas, Bronislovas Čechavičius, Evelina Dudutienė and Renata Butkutė

physics, 2023, 63
DOI: 10.3952/physics.2023.63.4.8

Whole-Body and Whole-Organ 3D Imaging of Hypoxia Using an Activatable Covalent Fluorescent Probe Compatible with Tissue Clearing

Daichi M. Sakamoto, Iori Tamura, Bo Yi, Sho Hasegawa, Yutaro Saito, Naoki Yamada, Yoichi Takakusagi, Shimpei I. Kubota, Minoru Kobayashi, Hiroshi Harada, Kenjiro Hanaoka, Masayasu Taki, Masaomi Nangaku, Kazuki Tainaka and Shinsuke Sando

ACS Nano, 2024, 18, 5167
DOI: 10.1021/acsnano.3c12716

Aggregation-induced emission (AIE)-Based nanocomposites for intracellular biological process monitoring and photodynamic therapy

Xiangfang Lin, Wei Li, Yongqiang Wen, Lei Su and Xueji Zhang

Biomaterials, 2022, 287, 121603
DOI: 10.1016/j.biomaterials.2022.121603

Chemiluminescent 1,2‐Dioxetane Iridium Complexes for Near‐Infrared Oxygen Sensing

Husain N. Kagalwala, Jeni Gerberich, Chancellor J. Smith, Ralph P. Mason and Alexander R. Lippert

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202115704

Ratiometric G-quadruplex/hemin DNAzymes with low-dosage associative substrates

Rong Lai, Xingli Zeng, Qiuda Xu, Ying Xu, Xueni Li, Yulu Ru, Yilin Wang, Dandan Wang, Xiaoshun Zhou and Yong Shao

Analytica Chimica Acta, 2024, 1295, 342320
DOI: 10.1016/j.aca.2024.342320

Activatable Fluorescent-Photoacoustic Integrated Probes with Deep Tissue Penetration for Pathological Diagnosis and Therapeutic Evaluation of Acute Inflammation in Mice

Wenxiu Li, Rong Li, Rui Chen, Sixin Ai, Huayong Zhu, Ling Huang and Weiying Lin

Anal. Chem., 2022, 94, 7996
DOI: 10.1021/acs.analchem.2c01048

Activity‐based Photoacoustic Probes Reveal Elevated Intestinal MGL and FAAH Activity in a Murine Model of Obesity

Melissa Y. Lucero, Sarah H. Gardner, Anuj K. Yadav, Austin Borri, Zhenxiang Zhao and Jefferson Chan

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202211774

Achieving deep red to near-infrared electroluminescence in platinum complex through enhanced conjugation of the ligand

Cheng Zhang, Jialu Liu, Danfeng He, Keyue Xu, Yuanyuan Fang, Wei Sun and Wenjing Xiong

Journal of Organometallic Chemistry, 2025, 1031, 123613
DOI: 10.1016/j.jorganchem.2025.123613

NIR‐Activatable, Sequence‐Specific Metal‐Nucleic Acid Scaffolds for Responsive Uncaging

Arpit Sharma, Man Kshetri, Deepak Karna, Md Al Amin, Shirin Akter, Hanbin Mao and Yao‐Rong Zheng

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202514717