Issue 4, 2020

A fluorogenic probe for tracking GSH flux in developing neurons

Abstract

Understanding GSH flux in developing neurons is prerequisite to reveal its role in neuronal development but necessiates an ultrasensitive assay. By systematically exploring key structural factors determing probe sensitivity in live cells, we developed a fluorogenic probe capable of imaging subtle GSH fluctuations in developing neurons.

Graphical abstract: A fluorogenic probe for tracking GSH flux in developing neurons

Supplementary files

Article information

Article type
Communication
Submitted
02 oct. 2019
Accepted
27 nov. 2019
First published
27 nov. 2019
This article is Open Access
Creative Commons BY license

Chem. Commun., 2020,56, 515-518

A fluorogenic probe for tracking GSH flux in developing neurons

H. Zong, J. Peng, X. Li, M. Liu, Y. Hu, J. Li, Y. Zang, X. Li and T. D. James, Chem. Commun., 2020, 56, 515 DOI: 10.1039/C9CC07753G

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