Issue 25, 2016

A highly fluorescent AIE-active theranostic agent with anti-tumor activity to specific cancer cells

Abstract

A tetraphenylethene derivative with a structure resembling Tamoxifen is designed and synthesized as a theranostic agent for cell imaging and anti-breast cancer therapy. Its high brightness, excellent photostability and long-term cell tracing properties enable elucidation of its working mechanism and hence provide new insights into drug development.

Graphical abstract: A highly fluorescent AIE-active theranostic agent with anti-tumor activity to specific cancer cells

Supplementary files

Article information

Article type
Communication
Submitted
10 Ker. 2015
Accepted
07 Gen. 2016
First published
08 Gen. 2016

Nanoscale, 2016,8, 12520-12523

A highly fluorescent AIE-active theranostic agent with anti-tumor activity to specific cancer cells

Y. Zhao, R. T. K. Kwok, J. W. Y. Lam and B. Z. Tang, Nanoscale, 2016, 8, 12520 DOI: 10.1039/C5NR08782A

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