Issue 6, 2022
From the journal:

Chemical Communications

Bottom-up/cross-linking mass spectrometry via simplified sample processing on anion-exchange solid-phase extraction spin column†

Ayako Takemori, ORCID logo a   Yusuke Kawashima ORCID logo b  and  Nobuaki Takemori ORCID logo *a  

* Corresponding authors

a Division of Analytical Bio-Medicine, Advanced Research Support Center, Ehime University, Toon, Ehime, Japan
E-mail: takemori@m.ehime-u.ac.jp

b Department of Applied Genomics, Kazusa DNA Research Institute, Kisarazu, Chiba, Japan

Abstract

We introduce a simple single-column protein digestion method for low-microgram-level samples containing sodium dodecyl sulfate and Coomassie dye that can be completed within a few hours.

Graphical abstract: Bottom-up/cross-linking mass spectrometry via simplified sample processing on anion-exchange solid-phase extraction spin column

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Article information

DOI
https://doi.org/10.1039/D1CC05529A
Article type
Communication
Submitted
30 Gwen. 2021
Accepted
18 Du 2021
First published
12 Ker. 2021
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2022,58, 775-778

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Bottom-up/cross-linking mass spectrometry via simplified sample processing on anion-exchange solid-phase extraction spin column

A. Takemori, Y. Kawashima and N. Takemori, Chem. Commun., 2022, 58, 775 DOI: 10.1039/D1CC05529A

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