Issue 53, 2017

Laser post-ionisation combined with a high resolving power orbitrap mass spectrometer for enhanced MALDI-MS imaging of lipids

Abstract

Coupling laser post-ionisation with a high resolving power MALDI Orbitrap mass spectrometer has realised an up to ∼100-fold increase in the sensitivity and enhanced the chemical coverage for MALDI-MS imaging of lipids relative to conventional MALDI. This could constitute a major breakthrough for biomedical research.

Graphical abstract: Laser post-ionisation combined with a high resolving power orbitrap mass spectrometer for enhanced MALDI-MS imaging of lipids

Supplementary files

Article information

Article type
Communication
Submitted
27 Meur. 2017
Accepted
18 Mae 2017
First published
18 Mae 2017

Chem. Commun., 2017,53, 7246-7249

Laser post-ionisation combined with a high resolving power orbitrap mass spectrometer for enhanced MALDI-MS imaging of lipids

S. R. Ellis, J. Soltwisch, M. R. L. Paine, K. Dreisewerd and R. M. A. Heeren, Chem. Commun., 2017, 53, 7246 DOI: 10.1039/C7CC02325A

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