Issue 39, 2013
From the journal:

Chemical Communications

Stereoselective synthesis of aminoindanols via an efficient cascade aza-Michael–aldol reaction†‡

Hui Qian,a   Wanxiang Zhao,a   Herman H-Y. Sung,a   Ian D. Williamsa  and  Jianwei Sun*a  

* Corresponding authors

a Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, China
E-mail: sunjw@ust.hk
Fax: +852 23581594
Tel: +852 23587351

Abstract

An efficient organocatalyzed strategy for the synthesis of 3-amino-1-indanols has been developed. This method is complementary to the conventional Friedel–Crafts strategy. It is also applicable to the synthesis of enantioenriched 3-amino-1-indanols.

Graphical abstract: Stereoselective synthesis of aminoindanols via an efficient cascade aza-Michael–aldol reaction

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Article information

DOI
https://doi.org/10.1039/C2CC37102B
Article type
Communication
Submitted
29 Gwen. 2012
Accepted
02 Du 2012
First published
05 Du 2012

Chem. Commun., 2013,49, 4361-4363

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Stereoselective synthesis of aminoindanols via an efficient cascade aza-Michael–aldol reaction

H. Qian, W. Zhao, H. H-Y. Sung, I. D. Williams and J. Sun, Chem. Commun., 2013, 49, 4361 DOI: 10.1039/C2CC37102B

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