Issue 18, 2011

Functionalized carbon nanomaterials as nanocarriers for loading and delivery of a poorly water-soluble anticancer drug: a comparative study

Abstract

Carbon nanomaterials such as multiwalled carbon nanotubes (MWCNTs) and graphene oxide (GO) have been functionalized by highly hydrophilic and biocompatible poly(vinyl alcohol) (PVA) for loading and delivery of an anticancer drug, camptothecin (CPT). For the first time, CPT was loaded onto MWCNT–PVA and GO–PVA through π–π interactions and its capability to kill human breast and skin cancer cells was investigated.

Graphical abstract: Functionalized carbon nanomaterials as nanocarriers for loading and delivery of a poorly water-soluble anticancer drug: a comparative study

Supplementary files

Article information

Article type
Communication
Submitted
05 Gen. 2011
Accepted
14 Meur. 2011
First published
30 Meur. 2011

Chem. Commun., 2011,47, 5235-5237

Functionalized carbon nanomaterials as nanocarriers for loading and delivery of a poorly water-soluble anticancer drug: a comparative study

N. G. Sahoo, H. Bao, Y. Pan, M. Pal, M. Kakran, H. K. F. Cheng, L. Li and L. P. Tan, Chem. Commun., 2011, 47, 5235 DOI: 10.1039/C1CC00075F

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