Issue 7, 2004
From the journal:

Chemical Communications

Solvent-drop grinding: green polymorph control of cocrystallisation†

Andrew V. Trask,a   W. D. Samuel Motherwellb  and  William Jones*a  

* Corresponding authors

a Pfizer Institute for Pharmaceutical Materials Science, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK
E-mail: wj10@cam.ac.uk
Fax: 44 1223 336362
Tel: 44 1223 334468

b Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge, UK

Abstract

By grinding with a minimal addition of a solvent of appropriate polarity, control over the polymorphic outcome of a novel cocrystallisation involving the model pharmaceutical compound caffeine may be achieved.

Graphical abstract: Solvent-drop grinding: green polymorph control of cocrystallisation

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B400978A
Article type
Communication
Submitted
21 Gen. 2004
Accepted
20 Cʼhwe. 2004
First published
05 Meur. 2004

Chem. Commun., 2004, 890-891

Permissions

Request permissions

Solvent-drop grinding: green polymorph control of cocrystallisation

A. V. Trask, W. D. S. Motherwell and W. Jones, Chem. Commun., 2004, 890 DOI: 10.1039/B400978A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements