Issue 38, 2023

A magnetic field-driven multi-functional “medical ship” for intestinal tissue collection in vivo

Abstract

The incidence of intestinal cancer has risen significantly. Because of the many challenges posed by the complex environment of the intestine, it is difficult to diagnose accurately and painlessly using conventional methods, which requires the development of new body-friendly diagnostic methods. Micro- and nanomotors show great potential for biomedical applications in restricted environments. However, the difficulty of recycling has been a constraint in the collection of biological tissues for diagnostic purposes. Here, we propose a multi-functional “medical ship” (MFMS) that can be rapidly driven by a magnetic field and can reversibly “open” and “close” its internal storage space under NIR laser irradiation. It provides a transportation and recovery platform for micro- and nanomotors and cargoes. In addition, fast selection of the MFMS and magnetic nanoparticles (MNPs) can be realized through adjusting the strength and frequency of the external magnetic field. Rapid encapsulation of intestinal tissues by MNPs was achieved using a low-frequency rotating magnetic field. In addition, we demonstrated the controlled release of MNPs using the MFMS and the collection of intestinal tissues. The proposed MFMS is an intelligent and controllable transportation platform with a simple structure, which is expected to be a new tool for performing medical tasks within the digestive system.

Graphical abstract: A magnetic field-driven multi-functional “medical ship” for intestinal tissue collection in vivo

Supplementary files

Article information

Article type
Paper
Submitted
31 Goue. 2023
Accepted
07 Gwen. 2023
First published
08 Gwen. 2023

Nanoscale, 2023,15, 15831-15839

A magnetic field-driven multi-functional “medical ship” for intestinal tissue collection in vivo

J. Liu, Z. Huang, H. Yue, R. Zhuang, L. Li, X. Chang and D. Zhou, Nanoscale, 2023, 15, 15831 DOI: 10.1039/D3NR03770C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements