Issue 14, 2021

Designing lanthanide coordination nanoframeworks as X-ray responsive radiosensitizers for efficient cancer therapy

Abstract

A series of three-dimensional Ln-based coordination frameworks were designed and synthesized. After nanolization, they show great potential as efficient and low toxic X-ray responsive radiosensitizers for the treatment of cervical cancer. The experimental data showed that these Ln-based nanoframeworks induced G0/G1 arrest mainly through the increase of the intracellular ROS level.

Graphical abstract: Designing lanthanide coordination nanoframeworks as X-ray responsive radiosensitizers for efficient cancer therapy

Supplementary files

Article information

Article type
Research Article
Submitted
04 Ebr. 2021
Accepted
10 Mae 2021
First published
14 Mae 2021

Inorg. Chem. Front., 2021,8, 3433-3439

Designing lanthanide coordination nanoframeworks as X-ray responsive radiosensitizers for efficient cancer therapy

H. Zhang, K. Ye, X. Huang, X. Lin, L. Ma and T. Chen, Inorg. Chem. Front., 2021, 8, 3433 DOI: 10.1039/D1QI00442E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements