This review highlights the advances from the past decade that provide readers with essential tools for designing and implementing radical sulfonylation using SO2 surrogates in organic synthesis.
Development of novel and efficient synthetic methods to achieve valuable N-heterocycles from aryldiazonium salts has been an important research area in organic chemistry for several decades.
This review aims to systematically consolidate the recent advances in palladium-catalyzed sulfonylation via SO2 insertion, elucidate the underlying reaction mechanism, and highlight some unsolved challenges in this segment.
Ru(II)-photoredox-catalyzed arylative and arylsulfonylative radical cascades involving N′-arylidene-N-methacryloylhydrazides and diaryliodonium reagents to furnish functionalized pyrazolones are accomplished.
A highly regio- and diastereoselective, 4-CzIPN catalyzed alkyl sulfonylative cascade of alkynyl tethered cyclohexadienones with Hantzsch esters and DABSO was developed to access functionalized dihydrochromenones.