Rare earth elements (REEs) are critical components of modern technologies but present a notoriously difficult separation challenge. Truncation of a calcium-binding RTX domain reduces binding site heterogeneity, boosting REE affinity and selectivity.
A unified excluded volume model based upon the effective hard particle approximation is developed and used to quantitatively model previously published experimental measurements of the effect of adding high concentrations of an “inert” polymer on conformational transitions of the toxin protein RCL.
A bioinformatic search of calcium-binding domains led to the identification of high-capacity, high-affinity, and high-selectivity binders for REE separation and recovery.
This review gives a comprehensive understanding of the structural, thermodynamic and kinetic aspects of Ln3+-coordination by peptides and proteins, and discusses their emerging applications in imaging, Ln separation and recovery, and catalysis.
This review summarizes the design strategies and recent research progress of stimuli-responsive peptide hydrogels for biomedical applications.