High-level ab initio calculations of gas phase enthalpies of formation combined with enthalpies of sublimations estimated using descriptors of electrostatic potential allow predicting the enthalpies of formation of diaziridines in the solid phase.
Unprecedented migration reactivity; new convenient access to chiral azaheterocycles & chiral center is on the side chain.
A green and efficient method for the synthesis of glycine derivatives from amines, azodicarboxylates, and diazoalkanes has been developed. This multicomponent reaction occurred under mild conditions in the absence of any catalysts or additives.
A transition-metal-free method to access non-symmetric azo derivatives via cross-couplings of arylazo sulfones with Csp2–H and Csp3–H is reported. The results presented herein shed light on the unconventional utilization of arylazo sulfones.
A base-mediated (3+3)-annulation of diaziridines with in situ generated azaoxyallyl cations is described to produce 1,2,4-triazines under mild reaction conditions.