We describe the design and characterization of a novel SadP-scFv UCHT1 lectibody, a fusion protein consisting of the lectin SadP, which specifically binds to globotriaosylceramide, and the scFv UCHT1, recognizing the CD3 receptor on T cells.
Sepsis is a systemic organ dysfunction caused by an abnormal host infection response, and its high fatality rate is closely associated with uncontrolled inflammatory storms, immunological diseases, and multi-organ failure.
1,2-Disulfonimide monomers are key building blocks for next-generation gas separation membranes. Herein, the routes to their synthesis are proposed and investigated.
This review highlights the progress of thiol–disulfide exchange-directed protein assembly, a programmable and dynamic tool for constructing functional and adaptive protein-based materials.
In this review, we have discussed some features of protein aggregation during production, formulation and storage as well as stabilization strategies in protein engineering and computational methods to prevent aggregation.