The optimisation of a suitable mixed ligand dirhodium(II,II) catalyst for chemoselective hydroaminomethylation of olefins was carried out using four previously synthesised heteroleptic dirhodium(II,II) acetato-bipyridyl complexes (1–4).
Biomass-derived renewable olefins act as sustainable and cost-effective starting materials in the production of industrially valuable chemicals, such as aldehydes, amines and other compounds, through hydroformylation and related one-pot reactions.
Rh/sulfoxantphos-catalyzed hydroaminomethylation has been developed to afford corresponding linear amines with good yields (71–95%) with high regioselectivities (l/b up to 132.4) and excellent catalytic activities (TON of Rh catalyst up to 23 760).
A new generation of thermomorphic multiphase systems combines key advantages of homogeneous catalyst recycling: reactions proceed under monophasic conditions in green solvents, avoiding mass-transfer limitations and the need for extraction solvents.
We report here a highly efficient photoredox cobalt-catalyzed hydroaminomethylation of alkynes with aminals towards tertiary allyl amines.