This work investigates the allosteric regulation of Aspergillus niger fructosyltransferase (QU10-FTase). It reveals how environmental factors, like the Fe3O4 interface and temperature, influence catalytic activity through allosteric regulations.
Normal and oncogenic RAS signalling pathway along with inhibitors.
Protein prenylation typically involves linkage of the lipid via a thioether bond. Here we report the discovery of prenoylation, a thioester-linked modification. In the case of ALDH9A1, this modification may serve an important regulatory function.
The complex [PtCl2(cyclohexane-1R,2R-diamine)] has been combined with the histone deacetylase inhibitor valproic acid and the potential antimetastatic perillic acid in order to obtain a set of multiaction Pt(IV) antiproliferative agents.
Benzofuran moiety is the main component of many biologically active natural and synthetic heterocycles.