Design and fabrication of intracellular therapeutic cargo delivery systems based on nanomaterials: current status and future perspectives

Hong Ma, Fei Xing, Yuxi Zhou, Peiyun Yu, Rong Luo, Jiawei Xu, Zhou Xiang, Pol Maria Rommens, Xin Duan and Ulrike Ritz

J. Mater. Chem. B, 2023, 11, 7873
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Zeolitic imidazolate frameworks enhanced transfection efficiency of mRNA loaded lipid nanoparticles

Ruhani Singh, Kerri Bruce, Shen Y Heazlewood, Jacinta F White, Malisja de Vries, Benjamin W. Muir, Benjamin Cao, Xavier Mulet, Daniel Layton and Cara M. Doherty

J. Mater. Chem. B, 2025, 13, 10675
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Advances in metal ion–mediated macromolecular drug delivery

Ke Li, Jieru Yang, Ying Peng, Huiwen Zheng, Zhizhan Fu, Meiying Li, Wenhu Zhou and Guofeng Yu

International Journal of Pharmaceutics, 2026, 689, 126501
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Room-Temperature Synthesis of pH-Responsive MOF Nanocarriers for Targeted Drug Delivery in Cancer Therapy

Amir Kazemi, Mohammad Hossein Afshari, Hasan Baesmat, Saber Keshavarz, Fateme Zeinali, Shahla Zahiri, Elahe Torabi, Faranak Manteghi and Sohrab Rohani

J Polym Environ, 2025, 33, 1505
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Engineering zeolitic imidazolate framework-8 nanoparticles for smart drug delivery systems

Cuixiu Wu, Wanyuan Huang, Fengyi Du, Miaomiao Zhang and Hanliang Qian

Nano Ex., 2024, 5, 012003
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Design and construction of nanoengineered multifunctional microneedles with sustained-release properties for targeted microenvironment remodeling in diabetic bone regeneration

Heyi Gong, Sihan Ma, Boyuan Wang, Yue Liu, Xiao Han, Yu Wang, Duo Sun, Yadi Su, Junqi Wang and Jinghui Zhao

Materials Today Bio, 2025, 35, 102494
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Nanomaterials via ZIF-8: Preparations, catalytic and drug delivery applications

Kumkum Priyadarshini Sahu, Suryabhan Singh, Ashish Kumar Singh, Uday Pratap Azad, Dibya Yadav, Vinod Kumar and Sunil Kumar Singh

Chemical Engineering Journal, 2025, 508, 160663
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Novel Approach to Synthesis of CoFe2O4@ZIF-67 Nanohybrid and its Potential as a Controlled Release System of Doxorubicin Drug

Zahra Khomami and Mohammadreza Mansournia

BioNanoSci., 2025, 15
DOI: 10.1007/s12668-025-02184-y

A paradigm shift from penetration: Material-based solutions for multidimensional spatiotemporal, hypoxic, and optical challenges in cutaneous photodynamic therapy

Xun Feng, Hua Fan, Lubin Zhou, Zhilong Zhao, Mu Yang, Xinxing Sun and Yang Chen

Materials Today Bio, 2026, 37, 102872
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Molecularly imprinted polymers in zeolitic imidazolate frameworks: A comprehensive review

Ali Bakhshi, Mehrdad Roshan, Mohammad Sadegh Asgari, Fatemeh Bijari and Ali Maleki

Coordination Chemistry Reviews, 2025, 534, 216561
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Engineering magnetite (Fe3O4) nanoparticles: Controlled synthesis, surface functionalization, and multidisciplinary technological applications: A Review

Mahendra Kohale, Himanshu Inamdar, Kiran Kokate, Raju Ingale, Jayant Joshi, Deobrat Singh, Aavishkar Katti, Satish Polshettiwar, Rahul Aher and Sachin Kulkarni

Progress in Crystal Growth and Characterization of Materials, 2026, 72, 100698
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Green Synthesis of Zeolitic Imidazolate Framework (ZIF) Nanoparticles for Theranostics

Yan Shan Loo, Gaayatri Silvaraju, Nur Airin Syahira Johari, Nur Aininie Yusoh, Afiq Azil, Norazalina Saad, Mohd Basyaruddin Abdul Rahman and Nurul Akmarina Mohd Abdul Kamal

ChemistrySelect, 2025, 10
DOI: 10.1002/slct.202502535

Surface functionalization of nitinol with polydopamine-assisted heparin-loaded ZIF-8 nanoparticles for vascular stents applications

Xiaojun Liu, Hui Liu, Geng Min, Yan Zhang, Jingan Li and Kun Zhang

Surfaces and Interfaces, 2026, 93, 109453
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Biomedical Metal–Organic framework materials on antimicrobial therapy: Perspectives and challenges

Wenbin Hu, Qin Ouyang, Chenyi Jiang, Sida Huang, Nezamzadeh-Ejhieh Alireza, Dekang Guo, Jianqiang Liu and Yanqiong Peng

Materials Today Chemistry, 2024, 41, 102300
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Zeolitic Imidazolate Framework-8 Nanocomposite Hydrogels for Diabetic Wound Healing

Junran Yang, Xinglong Liu, Yan Tang, Xiaoyu Bi, Huiying He, Xiaohang Sun, Qi Sui, Donglin Li, Wencong Liu, Dadong Liang and Chuanbo Ding

ACS Appl. Nano Mater., 2025, 8, 469
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Zeolitic imidazolate frameworks (ZIF-8) as a carrier in a topical ocular delivery system for the treatment of ocular diseases

Phillip A. Harding, James H. Westbay, Ethan Fletcher, Xin Fan, Morgan V. DiLeo and Safdar Ali Amur

PLoS One, 2026, 21, e0346473
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Improving the drug delivery performance of ZIF-8 with amine functionalization as a 5-fluorouracil nanocarrier

Sahba Mirzanejad, Mojtaba Bagherzadeh, Arshad Bayrami, Hossein Daneshgar, Aida Bahrami and Majid Mahdavi

Sci Rep, 2025, 15
DOI: 10.1038/s41598-025-03542-2

Light-Driven Double-Layer Polydopamine-Coated Flexible Metal–Organic Frameworks: Balancing Antibacterial and Regenerative Functions

Detian Miao, Yan Wei, Qian Wu, Richard J. Miron, Jihua Chai and Yufeng Zhang

ACS Nano, 2025, 19, 32869
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Innovative Nanocomposite Scaffolds Containing ZIF-8 Nanoparticles for Improving Wound Healing: A Review

Parinaz Nezhad-Mokhtari, Reza Rahbarghazi, Hamed Hamishehkar, Peyman Asadi and Morteza Milani

J Polym Environ, 2024, 32, 6211
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ZIF-8-mediated block copolymer micelles and its application in drug delivery

Lingling Jia, Yecheng Feng, Wenjing Yang and Xubo Zhao

European Polymer Journal, 2024, 216, 113293
DOI: 10.1016/j.eurpolymj.2024.113293

A review of recent developments of metal–organic frameworks as combined biomedical platforms over the past decade

Mojtaba Moharramnejad, Rahime Eshaghi Malekshah, Ali Ehsani, Sajjad Gharanli, Mehrnaz Shahi, Saeed Alvani Alvan, Zahra Salariyeh, Maryam Nasr Azadani, Jebiti Haribabu, Zahra Salmanivand Basmenj, Ali Khaleghian, Hossein Saremi, Zahra Hassani and Elham Momeni

Advances in Colloid and Interface Science, 2023, 316, 102908
DOI: 10.1016/j.cis.2023.102908

Porphyrinic Metal–Organic Framework PCN-224 Nanoparticles for Colocalization of Nanoparticle-Cargo in the Skin and Enhancement of Sonodynamic Efficacy

Xinxing Sun, Qiuyue Wang, Hongyang Bao, Yitong Liu, Sicheng Yao, Mingming Li, Naiying Chen and Yang Chen

ACS Appl. Nano Mater., 2024, 7, 2614
DOI: 10.1021/acsanm.3c04675

Incorporating Fluorescent Organosilica and Zeolitic Imidazolate Frameworks into Periodic Mesoporous Organosilica for the Enhanced Cargo Delivery of 5‐Fluorouracil

Linh Ty Huynh, Thao Vy Thi Nguyen, Ngoc Xuan Dat Mai, Tan Le Hoang Doan, Han Hoang Do, Quyen Toan Pham, Tri Le Minh, Thuy Dieu Thi Ung and Linh Ho Thuy Nguyen

ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202304443