Multifunctional supramolecular vesicles for combined photothermal/photodynamic/hypoxia-activated chemotherapy

Qi Wang, Lu Tian, Jingzeng Xu, Bing Xia, Jie Li, Feng Lu, Xiaomei Lu, Wenjun Wang, Wei Huang and Quli Fan

Chem. Commun., 2018, 54, 10328
DOI: 10.1039/C8CC05560B

Facile construction of AIE-active pyridinyl-diphenylacrylonitrile derivatives with optical properties finely modulated by D–A regulation

Yipu Wang, Yanlang Zhong, Xinyi Zhang, Da-Hui Qu, Dong Mei and Ju Mei

Mater. Chem. Front., 2022, 6, 2103
DOI: 10.1039/D2QM00477A

Metal-enhancement study of dual functional photosensitizers with aggregation-induced emission and singlet oxygen generation

Mohammad Tavakkoli Yaraki, Fang Hu, Soroosh Daqiqeh Rezaei, Bin Liu and Yen Nee Tan

Nanoscale Adv., 2020, 2, 2859
DOI: 10.1039/D0NA00182A

Molecular-engineered highly photosensitive triarylphosphine oxide compounds for apoptosis imaging and selectively inducing apoptosis of tumor cells by photodynamic therapy

Shilu Zhang, Hongyu Chen, Bo Zhao, Ronglan Liu, Bing Wang, Xiaoming Zhang, Guowei Deng, Yingping Luo and Jun Liu

Biomater. Sci., 2022, 10, 3441
DOI: 10.1039/D2BM00462C

A novel furo[3,2-c]pyridine-based AIE photosensitizer for specific imaging and photodynamic ablation of Gram-positive bacteria

Ming-Yu Wu, Yun Wang, Li-Juan Wang, Jia-Li Wang, Feng-Wei Xia and Shun Feng

Chem. Commun., 2022, 58, 10392
DOI: 10.1039/D2CC04084K

Recent advances of AIE light-up probes for photodynamic therapy

Shanshan Liu, Guangxue Feng, Ben Zhong Tang and Bin Liu

Chem. Sci., 2021, 12, 6488
DOI: 10.1039/D1SC00045D

Sonocrystallization induced thermally activated delayed fluorescence via distortion of molecular geometry

Antonio Maggiore, Yangyang Qu, Piotr Pander, Fernando B. Dias, Gilles Clavier, Regis Guillot, Davide Altamura, Cinzia Giannini, Vincenzo Maiorano, Pierre Audebert and Fabien Miomandre

J. Mater. Chem. C, 2024, 12, 7943
DOI: 10.1039/D4TC00245H

Synthesis of tetraphenylethene-based D–A conjugated molecules with near-infrared AIE features, and their application in photodynamic therapy

Li Li, Gang Yuan, Qianjiao Qi, Cheng Lv, Jichao Liang, Hongjie Li, Lei Cao, Xiuhua Zhang, Shengfu Wang, Yu Cheng and Hanping He

J. Mater. Chem. B, 2022, 10, 3550
DOI: 10.1039/D1TB02598H

Molecular engineering to red-shift the absorption band of AIE photosensitizers and improve their ROS generation ability

Yuhui Zhang, Xiaohong Pan, Haixing Shi, Yaqi Wang, Wenzhen Liu, Liangzhi Cai, Le Wang, Huanhuan Wang and Zhuo Chen

J. Mater. Chem. B, 2023, 11, 3252
DOI: 10.1039/D2TB02829H

Design of superior phototheranostic agents guided by Jablonski diagrams

Guangxue Feng, Guo-Qiang Zhang and Dan Ding

Chem. Soc. Rev., 2020, 49, 8179
DOI: 10.1039/D0CS00671H

Nanoprobes with aggregation-induced emission for theranostics

Wenbo Wu and Zhen Li

Mater. Chem. Front., 2021, 5, 603
DOI: 10.1039/D0QM00617C

Synthesis of an AIEgen functionalized cucurbit[7]uril for subcellular bioimaging and synergistic photodynamic therapy and supramolecular chemotherapy

Jia Chen, Shengke Li, Zeyu Wang, Yating Pan, Jianwen Wei, Siyu Lu, Qing-Wen Zhang, Lian-Hui Wang and Ruibing Wang

Chem. Sci., 2021, 12, 7727
DOI: 10.1039/D1SC01139A

Photodynamic therapy: photosensitizers and nanostructures

Alberto Escudero, Carolina Carrillo-Carrión, Ma Carmen Castillejos, Elena Romero-Ben, Christian Rosales-Barrios and Noureddine Khiar

Mater. Chem. Front., 2021, 5, 3788
DOI: 10.1039/D0QM00922A

Red/NIR-emissive dicyanovinyl-decorated tetraphenylethylenes for biosensing, bioimaging, and biomedical applications

Yanyan Huang, Guanxin Zhang, Rui Zhao and Deqing Zhang

Chem. Commun., 2025, 61, 19209
DOI: 10.1039/D5CC04643B

Fluorescent thermometer based on a quinolinemalononitrile copolymer with aggregation-induced emission characteristics

Jinfeng Yang, Kaizhi Gu, Chuanxing Shi, Meng Li, Ping Zhao and Wei-Hong Zhu

Mater. Chem. Front., 2019, 3, 1503
DOI: 10.1039/C9QM00147F

Pyridinium-substituted tetraphenylethylene salt-based photosensitizers by varying counter anions: a highly efficient photodynamic therapy for cancer cell ablation and bacterial inactivation

Wei Xiong, Lingyun Wang, Xiaoli Chen, Hao Tang, Derong Cao, Guozhen Zhang and Wei Chen

J. Mater. Chem. B, 2020, 8, 5234
DOI: 10.1039/D0TB00888E

Simultaneous one-step regulation of planarization and donor rotation to enhance multi-modal imaging guided therapy

Yize Zhang, Junjun Wang, Shen Wang, Xiaojiao Zhu, Zhipeng Yu, Zhichao Wu, Jianhua Yu and Hongping Zhou

Mater. Chem. Front., 2022, 6, 2921
DOI: 10.1039/D2QM00568A

Near-infrared light excited photodynamic anticancer therapy based on UCNP@AIEgen nanocomposite

Shihui Ding, Wenbo Wu, Tingting Peng, Wen Pang, Pengfei Jiang, Qiuqiang Zhan, Shuhong Qi, Xunbin Wei, Bobo Gu and Bin Liu

Nanoscale Adv., 2021, 3, 2325
DOI: 10.1039/D0NA00985G

Molecular engineering of aggregation-induced emission enhanced photosensitizers to boost the theranostic performance in photodynamic therapy

Sauraj, Ji Hee Kang, O Hyun Lee, Anindita De, Dongyun Shin and Young Tag Ko

J. Mater. Chem. B, 2026, 14, 1549
DOI: 10.1039/D5TB02266E

PEGylated AIEgen molecular probe for hypoxia-mediated tumor imaging and photodynamic therapy

Jun Li, Wei Liu, Zuhao Li, Yingcai Hu, Jinfeng Yang and Jishan Li

Chem. Commun., 2021, 57, 4710
DOI: 10.1039/D1CC00967B

The fast-growing field of photo-driven theranostics based on aggregation-induced emission

Zhijun Zhang, Miaomiao Kang, Hui Tan, Nan Song, Meng Li, Peihong Xiao, Dingyuan Yan, Liping Zhang, Dong Wang and Ben Zhong Tang

Chem. Soc. Rev., 2022, 51, 1983
DOI: 10.1039/D1CS01138C

Visible-Light -Triggered Fluorescent Organic Nanoparticles for Chemo-Photodynamic Therapy with Real-Time Cellular Imaging

C. Parthiban, Pavithra M., Vinod Kumar Reddy L., Dwaipayan Sen, Melvin Samuel S. and N. D. Pradeep Singh

ACS Appl. Nano Mater., 2018, 1, 6281
DOI: 10.1021/acsanm.8b01495

Single-Component Fluorescent Organic Nanoparticles with Four-Armed Phototriggers for Chemo-Photodynamic Therapy and Cellular Imaging

C. Parthiban, Pavithra M., L. Vinod Kumar Reddy, Dwaipayan Sen and N. D. Pradeep Singh

ACS Appl. Nano Mater., 2019, 2, 3728
DOI: 10.1021/acsanm.9b00630

Membrane‐Anchoring Photosensitizer with Aggregation‐Induced Emission Characteristics for Combating Multidrug‐Resistant Bacteria

Huan Chen, Shengliang Li, Min Wu, Kenry, Zhongming Huang, Chun‐Sing Lee and Bin Liu

Angew Chem Int Ed, 2020, 59, 632
DOI: 10.1002/anie.201907343

Carrier-Free Hybrid DNA Nanoparticles for Light-Induced Self-Delivery of Functional Nucleic Acid Enzymes

Leilei Shi, Wenbo Wu, Yukun Duan, Li Xu, Sha Li, Xihui Gao and Bin Liu

ACS Nano, 2021, 15, 1841
DOI: 10.1021/acsnano.0c10045

Tpy-Mn(II)-Tpy (Tpy = 2,2′:6′,2″-terpyridine)-Based Pentagonal Prism for Green Photodriven Oxidation

Qixia Bai, Zhiyuan Jiang, Yuming Guan, Qingwu Long, Bokai Liao, Ting-Zheng Xie, Tun Wu, Zhe Zhang and Pingshan Wang

Inorg. Chem., 2023, 62, 5095
DOI: 10.1021/acs.inorgchem.2c04214

Photosensitizer-Bacteria Biohybrids Promote Photodynamic Cancer Cell Ablation and Intracellular Protein Delivery

Min Wu, Wenbo Wu, Yukun Duan, Xueqi Li, Guobin Qi and Bin Liu

Chem. Mater., 2019, 31, 7212
DOI: 10.1021/acs.chemmater.9b01518

An Aptamer‐Conjugated AIEgen for Targeted Bioimaging and Photodynamic Therapy of Cancer Cells

Yi Chen, Maochao Zhao, Pan Yang, Yi Wang, Yuan Zou and Wenjun Miao

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202501209

Metal-Free White Light-Emitting Fluorescent Material Based on Simple Pillar[5]arene-tripodal Amide System and Theoretical Insights on Its Assembly and Fluorescent Properties

Hai-Long Yang, Zhao-Hui Li, Pei-Pei Liu, Xiao-Wen Sun, Zhong-Hui Wang, Hong Yao, You-Ming Zhang, Tai-Bao Wei and Qi Lin

Langmuir, 2020, 36, 13469
DOI: 10.1021/acs.langmuir.0c02120

AIE-Active Photosensitizers: Manipulation of Reactive Oxygen Species Generation and Applications in Photodynamic Therapy

Hao Yu, Binjie Chen, Huiming Huang, Zhentao He, Jiangman Sun, Guan Wang, Xinggui Gu and Ben Zhong Tang

Biosensors, 2022, 12, 348
DOI: 10.3390/bios12050348

Polymerization-Enhanced Photophysical Performances of AIEgens for Chemo/Bio-Sensing and Therapy

Shanshan Huang, Guogang Shan, Chao Qin and Shunjie Liu

Molecules, 2022, 28, 78
DOI: 10.3390/molecules28010078

Tumor-Activated and Metal–Organic Framework Assisted Self-Assembly of Organic Photosensitizers

Yuanbo Wang, Leilei Shi, Dou Ma, Shidang Xu, Wenbo Wu, Li Xu, Majid Panahandeh-Fard, Xinyuan Zhu, Bo Wang and Bin Liu

ACS Nano, 2020, 14, 13056
DOI: 10.1021/acsnano.0c04518

Aggregation-induced emission shining in the biomedical field: From bench to bedside

Yishen Liu, Qingrong Chen, Yidan Sun, Luojia Chen, Yuncong Yuan and Meijia Gu

Engineered Regeneration, 2021, 2, 206
DOI: 10.1016/j.engreg.2021.11.001

Acceptor substitution engineering of BODIPY-based organic photosensitizers with aggregation-induced emission for organelle localization and photodynamic anticancer therapy

Chaojie Shen, Mintao Xie, Liying Pan, Binbin Wu, Wenxuan Zhang, Yuying Yuan, Yuan Chen, Yun-Yun Quan, Xiaoxia Ye and Zu-Sheng Huang

Materials & Design, 2023, 228, 111838
DOI: 10.1016/j.matdes.2023.111838

Nanobody modified high-performance AIE photosensitizer nanoparticles for precise photodynamic oral cancer therapy of patient-derived tumor xenograft

Wenbo Wu, Leilei Shi, Yukun Duan, Shidang Xu, Lingyue Shen, Ting Zhu, Lidan Hou, Xiangjun Meng and Bin Liu

Biomaterials, 2021, 274, 120870
DOI: 10.1016/j.biomaterials.2021.120870

Tumor‐Activated Photosensitization and Size Transformation of Nanodrugs

Yuanbo Wang, Leilei Shi, Wenbo Wu, Guobin Qi, Xinyuan Zhu and Bin Liu

Adv Funct Materials, 2021, 31
DOI: 10.1002/adfm.202010241

A Multimodal Antibacterial Platform for Visualizing Reactive Oxygen Species Generation and Promoting Wound Healing

Xiaodong He, Ziyi Xu, Huajun Wu, Gnanasekar Sathishkumar, Kai Zhang, Xi Rao, Mahshid Kharaziha, Nianbing Li, En‐Tang Kang and Liqun Xu

Adv Funct Materials, 2024, 34
DOI: 10.1002/adfm.202404708

Biomedical applications of the engineered AIEgen-lipid nanostructure in vitro and in vivo

Meng Suo, Tianfu Zhang and Xing-Jie Liang

Prog. Biomed. Eng., 2025, 7, 012006
DOI: 10.1088/2516-1091/ad9aeb

Light‐Induced Self‐Escape of Spherical Nucleic Acid from Endo/Lysosome for Efficient Non‐Cationic Gene Delivery

Leilei Shi, Wenbo Wu, Yukun Duan, Li Xu, Yingying Xu, Lidan Hou, Xiangjun Meng, Xinyuan Zhu and Bin Liu

Angewandte Chemie, 2020, 132, 19330
DOI: 10.1002/ange.202006890

An Active Self‐Mitochondria‐Targeting Cyanine Immunomodulator for Near‐Infrared II Fluorescence Imaging‐Guided Synergistic Photodynamic Immunotherapy

Jin‐Feng Yu, Yu Wen and Ming Li

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202401061

Aggregation-induced emission active luminescent polymeric nanofibers: From design, synthesis, fluorescent mechanism to applications

Xinhui Zhai, Rong Chen and Weiyang Shen

TrAC Trends in Analytical Chemistry, 2022, 146, 116502
DOI: 10.1016/j.trac.2021.116502

Amphiphilic Rhodamine Nano-assembly as a Type I Supramolecular Photosensitizer for Photodynamic Therapy

Hajime Shigemitsu, Kazuhide Sato, Satomi Hagio, Youhei Tani, Tadashi Mori, Kei Ohkubo, Yasuko Osakada, Mamoru Fujitsuka and Toshiyuki Kida

ACS Appl. Nano Mater., 2022, 5, 14954
DOI: 10.1021/acsanm.2c03192

Membrane‐Anchoring Photosensitizer with Aggregation‐Induced Emission Characteristics for Combating Multidrug‐Resistant Bacteria

Huan Chen, Shengliang Li, Min Wu, Kenry, Zhongming Huang, Chun‐Sing Lee and Bin Liu

Angewandte Chemie, 2020, 132, 642
DOI: 10.1002/ange.201907343

Aggregation-Induced Emission (AIE) Dots: Emerging Theranostic Nanolights

Guangxue Feng and Bin Liu

Acc. Chem. Res., 2018, 51, 1404
DOI: 10.1021/acs.accounts.8b00060

Molecular Engineered Squaraine Nanoprobe for NIR-II/Photoacoustic Imaging and Photothermal Therapy of Metastatic Breast Cancer

Defan Yao, Yanshu Wang, Rongfeng Zou, Kexin Bian, Pei Liu, Shuzhan Shen, Weitao Yang, Bingbo Zhang and Dengbin Wang

ACS Appl. Mater. Interfaces, 2020, 12, 4276
DOI: 10.1021/acsami.9b20147

Photosensitizers with Aggregation‐Induced Emission: Materials and Biomedical Applications

Fang Hu, Shidang Xu and Bin Liu

Advanced Materials, 2018, 30
DOI: 10.1002/adma.201801350

A Cross‐linked Conjugated Polymer Photosensitizer Enables Efficient Sunlight‐Induced Photooxidation

Wenbo Wu, Shidang Xu, Guobin Qi, Han Zhu, Fang Hu, Zitong Liu, Deqing Zhang and Bin Liu

Angewandte Chemie, 2019, 131, 3094
DOI: 10.1002/ange.201811067

Molecular Engineering of Efficient Singlet Oxygen Generators with Near‐Infrared AIE Features for Mitochondrial Targeted Photodynamic Therapy

Gang Yuan, Cheng Lv, Jichao Liang, Xinxin Zhong, Yuan Li, Jiacun He, Anjing Zhao, Li Li, Yuanhe Shao, Xiuhua Zhang, Shengfu Wang, Yu Cheng and Hanping He

Adv Funct Materials, 2021, 31
DOI: 10.1002/adfm.202104026

Structure and functions of Aggregation-Induced Emission-Photosensitizers in anticancer and antimicrobial theranostics

Heidi Abrahamse, Michael R. Hamblin and Sajan George

Front. Chem., 2022, 10
DOI: 10.3389/fchem.2022.984268

A turn-on type vapofluorochromic methoxybenzylidene methanone Schiff base applied to wearable VOC sensor and smartphone-based detection

Yu Zhang, Xinyi Zhao, Lingfan Xu, Yuai Duan, Jing Yuan, Zhongfeng Li and Tianyu Han

Sensors and Actuators B: Chemical, 2024, 399, 134834
DOI: 10.1016/j.snb.2023.134834

AIE-featured tetraphenylethylene nanoarchitectures in biomedical application: Bioimaging, drug delivery and disease treatment

Kothanahally S. Sharath Kumar, Yarabahally R. Girish, Milad Ashrafizadeh, Sepideh Mirzaei, Kadalipura P. Rakesh, Mohammad Hossein Gholami, Amirhossein Zabolian, Kiavash Hushmandi, Gorka Orive, Firoz Babu Kadumudi, Alireza Dolatshahi-Pirouz, Vijay Kumar Thakur, Ali Zarrabi, Pooyan Makvandi and Kanchugarakoppal S. Rangappa

Coordination Chemistry Reviews, 2021, 447, 214135
DOI: 10.1016/j.ccr.2021.214135

Sterically Twisted Mitochondria‐Targeting Photosensitizers for Augmented Near‐Infrared II Fluorescence‐Guided Photodynamic Immunotherapy

Jin‐Feng Yu, Yu Wen and Ming Li

Adv Funct Materials, 2024, 34
DOI: 10.1002/adfm.202402663

AIE-active photosensitizers for concomitant fluorescence visualization and efficient photodynamic elimination of multidrug-resistant bacteria

Shaoling Li, Senlin Peng, Shuning Yu, Meiliang Zhi, Xiang Su, Qilong Zhang, Carl Redshaw and Xing Feng

Dyes and Pigments, 2024, 231, 112388
DOI: 10.1016/j.dyepig.2024.112388

ONOO– and ClO– Responsive Organic Nanoparticles for Specific in Vivo Image-Guided Photodynamic Bacterial Ablation

Wenbo Wu, Duo Mao, Xiaolei Cai, Yukun Duan, Fang Hu, Deling Kong and Bin Liu

Chem. Mater., 2018, 30, 3867
DOI: 10.1021/acs.chemmater.8b01320

Aggregation-induced emission (AIE)-guided dynamic assembly for disease imaging and therapy

He-Ping Wang, Xi Chen, Yi-Lin Qi, Li-Wen Huang, Chun-Xiao Wang, Dan Ding and Xue Xue

Advanced Drug Delivery Reviews, 2021, 179, 114028
DOI: 10.1016/j.addr.2021.114028

Bioorthogonal strategy-triggered In situ co-activation of aggregation-induced emission photosensitizers and chemotherapeutic prodrugs for boosting synergistic chemo-photodynamic-immunotherapy

Yu Teng, Dianyu Wang, Ziyu Yang, Ruxuan Wang, Shuyi Ning, Rongrong Zhang, Hong Yang, Xinchi Feng, Jianfeng Liu, Lijun Yang and Yulin Tian

Biomaterials, 2025, 317, 123092
DOI: 10.1016/j.biomaterials.2025.123092

Engineered Cell-Assisted Photoactive Nanoparticle Delivery for Image-Guided Synergistic Photodynamic/Photothermal Therapy of Cancer

Peng Wang, Wenbo Wu, Ruifang Gao, Han Zhu, Juan Wang, Renle Du, Xiaoyu Li, Chenglan Zhang, Shaokui Cao and Rong Xiang

ACS Appl. Mater. Interfaces, 2019, 11, 13935
DOI: 10.1021/acsami.9b00022

A novel strong AIE bi-component hydrogel as a multi-functional supramolecular fluorescent material

Hai-Long Yang, Qin-Peng Zhang, You-Ming Zhang, Guan-Fei Gong, Yan-Yan Chen, Qi-Zhou, Hong Yao, Tai-Bao Wei and Qi Lin

Dyes and Pigments, 2019, 171, 107745
DOI: 10.1016/j.dyepig.2019.107745

Enhancing Photodynamic Therapy Efficacy of Upconversion-Based Nanoparticles Conjugated with a Long-Lived Triplet Excited State Iridium(III)-Naphthalimide Complex: Toward Highly Enhanced Hypoxia-Inducible Factor-1

Jian Zhao, Shuchen Sun, Xiaoyan Li, Wenjing Zhang and Shaohua Gou

ACS Appl. Bio Mater., 2020, 3, 252
DOI: 10.1021/acsabm.9b00774

Strategies to construct efficient singlet oxygen-generating photosensitizers

E Pang, Shaojing Zhao, Benhua Wang, Guangle Niu, Xiangzhi Song and Minhuan Lan

Coordination Chemistry Reviews, 2022, 472, 214780
DOI: 10.1016/j.ccr.2022.214780

Polymerization-Enhanced Two-Photon Photosensitization for Precise Photodynamic Therapy

Shaowei Wang, Wenbo Wu, Purnima Manghnani, Shidang Xu, Yuanbo Wang, Chi Ching Goh, Lai Guan Ng and Bin Liu

ACS Nano, 2019, 13, 3095
DOI: 10.1021/acsnano.8b08398

NIR-Triggered “OFF/ON” Photodynamic Therapy through a Upper Critical Solution Temperature Block Copolymer

Dawei Jiang, Chao Chen, Yudong Xue, Hongliang Cao, Chaochao Wang, Guoliang Yang, Yun Gao, Ping Wang and Weian Zhang

ACS Appl. Mater. Interfaces, 2019, 11, 37121
DOI: 10.1021/acsami.9b12889

AIEgen-coupled upconversion nanoparticles eradicate solid tumors through dual-mode ROS activation

Duo Mao, Fang Hu, Zhigao Yi, Kenry, Shidang Xu, Shuangqian Yan, Zichao Luo, Wenbo Wu, Zhihong Wang, Deling Kong, Xiaogang Liu and Bin Liu

Sci. Adv., 2020, 6
DOI: 10.1126/sciadv.abb2712

Molecular Engineering of Near‐Infrared‐II Photosensitizers with Steric‐Hindrance Effect for Image‐Guided Cancer Photodynamic Therapy

Shuai Gao, Sheng Yu, Yongming Zhang, Aihua Wu, Sihang Zhang, Guoguang Wei, Hao Wang, Zeyu Xiao and Wei Lu

Adv Funct Materials, 2021, 31
DOI: 10.1002/adfm.202008356

Highly Efficient Near-Infrared Photosensitizers with Aggregation-Induced Emission Characteristics: Rational Molecular Design and Photodynamic Cancer Cell Ablation

Dugang Chen, Zi Long, Cheng Zhong, Li Chen, Yecheng Dang, Jing-Jing Hu, Xiaoding Lou and Fan Xia

ACS Appl. Bio Mater., 2021, 4, 5231
DOI: 10.1021/acsabm.1c00398

Click Synthesis Enabled Sulfur Atom Strategy for Polymerization‐Enhanced and Two‐Photon Photosensitization

Chongyang Li, Junkai Liu, Yingjuan Hong, Runfeng Lin, Zicheng Liu, Ming Chen, Jacky W. Y. Lam, Guo‐Hong Ning, Xiuli Zheng, Anjun Qin and Ben Zhong Tang

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202202005

Highly Twisted Conformation Thiopyrylium Photosensitizers for In Vivo Near Infrared‐II Imaging and Rapid Inactivation of Coronavirus

Yishen Liu, Meijia Gu, Qihang Ding, Zhiyun Zhang, Wanxia Gong, Yuncong Yuan, Xiaofei Miao, Huili Ma, Xuechuan Hong, Wenbo Hu and Yuling Xiao

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202214875

Click Synthesis Enabled Sulfur Atom Strategy for Polymerization‐Enhanced and Two‐Photon Photosensitization

Chongyang Li, Junkai Liu, Yingjuan Hong, Runfeng Lin, Zicheng Liu, Ming Chen, Jacky W. Y. Lam, Guo‐Hong Ning, Xiuli Zheng, Anjun Qin and Ben Zhong Tang

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202202005

AIE-based cancer theranostics

Meng Gao and Ben Zhong Tang

Coordination Chemistry Reviews, 2020, 402, 213076
DOI: 10.1016/j.ccr.2019.213076

Polymerization-Enhanced Photosensitization

Wenbo Wu, Duo Mao, Shidang Xu, Kenry, Fang Hu, Xueqi Li, Deling Kong and Bin Liu

Chem, 2018, 4, 1937
DOI: 10.1016/j.chempr.2018.06.003

Modulating Cell Specificity and Subcellular Localization by Molecular Charges and Lipophilicity

Guangxue Feng, Can Wang, Chengjian Chen, Yutong Pan, Min Wu, Yuanbo Wang, Jie Liu and Bin Liu

Chem. Mater., 2020, 32, 10383
DOI: 10.1021/acs.chemmater.0c02700

Novel D-π-A-D Type aggregation induced emission luminogens based nanoparticles as efficient 1O2 photosensitizer and bright NIR imaging agent

Wen Li, Meina Huang, Yuan Li, Zhigang Yang and Junle Qu

Dyes and Pigments, 2021, 186, 109041
DOI: 10.1016/j.dyepig.2020.109041

Two‐Photon Mediated Cancer Therapy: A Comprehensive Review on Two‐Photon Photodynamic Therapy and Two‐Photon‐Activated Therapeutic Delivery Systems

Amir Soleimany, Delaram Kargari Aghmiouni, Masomeh Amirikhah, Mohammad Ali Shokrgozar, Sepideh Khoee and Bruno Sarmento

Adv Funct Materials, 2024, 34
DOI: 10.1002/adfm.202408594

BOPHY-Based Aggregation-Induced-Emission Nanoparticle Photosensitizers for Photodynamic Therapy

Fangyuan Lv, Dapeng Liu, Wen-heng Zheng, Yanliang Zhao and Fengling Song

ACS Appl. Nano Mater., 2021, 4, 6012
DOI: 10.1021/acsanm.1c00862

Strategies in boosting photosensitization for biomedical applications

Ming Chen, Ryan T. K. Kwok, Youhong Tang and Dan Ding

Sci. China Chem., 2022, 65, 647
DOI: 10.1007/s11426-021-1176-5

Highly Twisted Conformation Thiopyrylium Photosensitizers for In Vivo Near Infrared‐II Imaging and Rapid Inactivation of Coronavirus

Yishen Liu, Meijia Gu, Qihang Ding, Zhiyun Zhang, Wanxia Gong, Yuncong Yuan, Xiaofei Miao, Huili Ma, Xuechuan Hong, Wenbo Hu and Yuling Xiao

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202214875

A Bifunctional Aggregation‐Induced Emission Luminogen for Monitoring and Killing of Multidrug‐Resistant Bacteria

Ying Li, Zheng Zhao, Jiangjiang Zhang, Ryan T. K. Kwok, Sheng Xie, Rongbing Tang, Yuexiao Jia, Junchuan Yang, Le Wang, Jacky W. Y. Lam, Wenfu Zheng, Xingyu Jiang and Ben Zhong Tang

Adv Funct Materials, 2018, 28
DOI: 10.1002/adfm.201804632

A Highly Efficient Aggregation-induced Emission Photosensitizer for Photodynamic Combat of Multidrug-resistant Bacteria

Qian Zou, Jia-Li Wang, Ming-Yu Wu, Chuen Kam, Sin-Ying Lee, Shun Feng and Sijie Chen

Chem. Res. Chin. Univ., 2021, 37, 150
DOI: 10.1007/s40242-021-0393-2

Engineering Diselenide-IR780 Homodimeric Nanoassemblies with Enhanced Photodynamic and Immunotherapeutic Effects for Triple-Negative Breast Cancer Treatment

Yifan Xue, Kaijin Chen, You Chen, Yadong Liu, Junjie Tang, Xiaoge Zhang and Jie Liu

ACS Nano, 2023, 17, 22553
DOI: 10.1021/acsnano.3c06290

Recent Advances in Hypoxia‐Overcoming Strategy of Aggregation‐Induced Emission Photosensitizers for Efficient Photodynamic Therapy

Huan Chen, Yingpeng Wan, Xiao Cui, Shengliang Li and Chun‐Sing Lee

Adv Healthcare Materials, 2021, 10
DOI: 10.1002/adhm.202101607

Multifunctional agents based on 3‐dicycanovinylindan‐1‐one acceptor: Molecular design and phototheranostic application

Najia Zhu, Yajing Jiang and Wenbo Wu

Luminescence, 2024, 39
DOI: 10.1002/bio.4708

In vivo photodynamic therapy based on Near-Infrared AIE cationic polymers

Zisong Cong, Shengjie Xie, Zhuoran Jiang, Shuo Zheng, Weihua Wang, Wenyan Wang and Heng Song

Chemical Engineering Journal, 2022, 431, 133748
DOI: 10.1016/j.cej.2021.133748

Metal–Organic Framework Assisted and Tumor Microenvironment Modulated Synergistic Image‐Guided Photo‐Chemo Therapy

Yuanbo Wang, Wenbo Wu, Duo Mao, Cathleen Teh, Bo Wang and Bin Liu

Adv Funct Materials, 2020, 30
DOI: 10.1002/adfm.202002431

A structure-guided strategy to design Golgi apparatus-targeted type-I/II aggregation-induced emission photosensitizers for efficient photodynamic therapy

Xing Zhao, Xi Wu, Ranran Shang, Huachao Chen and Ninghua Tan

Acta Biomaterialia, 2024, 183, 235
DOI: 10.1016/j.actbio.2024.05.034

Construction of Triphenylamine-Based Aggregation-Induced Emission Luminogens for Lysosomes Imaging and Its Application in the Photodynamic Therapy of Cancer Cells

Zhanguo Sun, Bin Liu and Huijun Liu

Molecules, 2025, 30, 2272
DOI: 10.3390/molecules30112272

Precise Molecular Engineering of Photosensitizers with Aggregation‐Induced Emission over 800 nm for Photodynamic Therapy

Wenbo Wu, Duo Mao, Shidang Xu, Majid Panahandeh‐Fard, Yukun Duan, Fang Hu, Deling Kong and Bin Liu

Adv Funct Materials, 2019, 29
DOI: 10.1002/adfm.201901791

Articulated Structures of D-A Type Dipolar Dye with AIEgen: Synthesis, Photophysical Properties, and Applications

Na Hee Kim, Byeong Wook Kim, Youngseo Kim, Junho K. Hur, Junyang Jung, Yohan Oh, Sungnam Park, B. Moon Kim and Dokyoung Kim

Materials, 2020, 13, 1939
DOI: 10.3390/ma13081939

Aggregation‐enhanced theranostics: AIE sparkles in biomedical field

Miaomiao Kang, Zhijun Zhang, Nan Song, Meng Li, Panpan Sun, Xiaohui Chen, Dong Wang and Ben Zhong Tang

Aggregate, 2020, 1, 80
DOI: 10.1002/agt2.7

Enhanced singlet oxygen generation over Au modified Zr-MOF photocatalyst for efficient photocatalytic degradation of organic pollutants

Xin Jiang, Aiyu Yang, Lei Tang, Caixia Zhong and Zhenxing Zeng

Res Chem Intermed, 2026, 52, 151
DOI: 10.1007/s11164-025-05794-z

A Cross‐linked Conjugated Polymer Photosensitizer Enables Efficient Sunlight‐Induced Photooxidation

Wenbo Wu, Shidang Xu, Guobin Qi, Han Zhu, Fang Hu, Zitong Liu, Deqing Zhang and Bin Liu

Angew Chem Int Ed, 2019, 58, 3062
DOI: 10.1002/anie.201811067

Organic Photo-antimicrobials: Principles, Molecule Design, and Applications

Bei Ran, Zuokai Wang, Wenlin Cai, Lei Ran, Wenxi Xia, Weijian Liu and Xiaojun Peng

J. Am. Chem. Soc., 2021, 143, 17891
DOI: 10.1021/jacs.1c08679

Golgi apparatus-targeted aggregation-induced emission luminogens for effective cancer photodynamic therapy

Minglun Liu, Yuncong Chen, Yan Guo, Hao Yuan, Tongxiao Cui, Shankun Yao, Suxing Jin, Huanhuan Fan, Chengjun Wang, Ran Xie, Weijiang He and Zijian Guo

Nat Commun, 2022, 13
DOI: 10.1038/s41467-022-29872-7

Emerging Strategies in Enhancing Singlet Oxygen Generation of Nano-Photosensitizers Toward Advanced Phototherapy

Mohammad Tavakkoli Yaraki, Bin Liu and Yen Nee Tan

Nano-Micro Lett., 2022, 14
DOI: 10.1007/s40820-022-00856-y

Platelet membrane camouflaged AIEgen‐mediated photodynamic therapy improves the effectiveness of anti‐PD‐L1 immunotherapy in large‐burden tumors

Jun Dai, Meng Wu, Yating Xu, Hongming Yao, Xiaoding Lou, Yuning Hong, Jian Zhou, Fan Xia and Shixuan Wang

Bioengineering & Transla Med, 2023, 8
DOI: 10.1002/btm2.10417

Molecular Engineering of D‐π‐A Conjugate with N‐Heterocycle Purine for Enhanced ROS Generation and Photodynamic Therapy

Xue Chen, Lei Shi, Xiao‐Yun Ran, Ji‐Xuan Xu, Li‐Na Zhang, Qing‐Quan Kong, Xiao‐Qi Yu and Kun Li

Adv Funct Materials, 2024, 34
DOI: 10.1002/adfm.202400728

Bright Aggregation-Induced Emission Nanoparticles for Two-Photon Imaging and Localized Compound Therapy of Cancers

Ying Li, Rongbing Tang, Xiaoyan Liu, Junyi Gong, Zujin Zhao, Zonghai Sheng, Jiangjiang Zhang, Xuanyu Li, Guangle Niu, Ryan T. K. Kwok, Wenfu Zheng, Xingyu Jiang and Ben Zhong Tang

ACS Nano, 2020, 14, 16840
DOI: 10.1021/acsnano.0c05610

NIR‐II Self‐Luminous Molecular Probe for In Vivo Inflammation Tracking and Cancer PDT Effect Self‐Evaluating

Meng Yuan, Xiao Fang, Jianyong Liu, Kaiqiong Yang, Shenggan Xiao, Sheng Yang, Wei Du and Jibin Song

Small, 2023, 19
DOI: 10.1002/smll.202206666

Single-Cell Detection of Circulating Tumor Cells by a Proximity-Enabled Singlet-Oxygen Chemiluminescence Assay

Fei Chen, Daian Chen, Ting Deng, Jishan Li and Jian-Hui Jiang

Anal. Chem., 2025, 97, 17668
DOI: 10.1021/acs.analchem.5c02883

A novel Schiff's base conjugate with multicolor changes in multiple states and its multipurpose applications for selective detection of Cu2+ in aggregated state and on silica gel strip

Mingguang Zhu, Shizhou Huang, Meihui Chen, Yangping Li and Min Zhong

Optical Materials, 2022, 127, 112288
DOI: 10.1016/j.optmat.2022.112288

Precise Molecular Design for High‐Performance Luminogens with Aggregation‐Induced Emission

Shidang Xu, Yukun Duan and Bin Liu

Advanced Materials, 2020, 32
DOI: 10.1002/adma.201903530

Multifunctionalized Tumor-Triggered Targeting Theranostic Nanoparticles as a Precision NIR Imaging-Guided Nanoplatform for Photothermal/Photodynamic Therapy

Xu Zhao, Kang-Kang Zhang, Li-Jian Chen, Zhen-Yu Wang and Xiu-Ping Yan

ACS Appl. Nano Mater., 2023, 6, 10501
DOI: 10.1021/acsanm.3c01473

Organic Mitoprobes based on Fluorogens with Aggregation‐Induced Emission

Xiaolei Cai, Fang Hu, Guangxue Feng, Ryan Tsz Kin Kwok, Bin Liu and Ben Zhong Tang

Israel Journal of Chemistry, 2018, 58, 860
DOI: 10.1002/ijch.201800031

Mechanism, structural design, modulation and applications of Aggregation-induced emission-based Metal-organic framework

Xinhui Zhai, Zongyao Cui and Weiyang Shen

Inorganic Chemistry Communications, 2022, 146, 110038
DOI: 10.1016/j.inoche.2022.110038

The Application of Aggregation-Induced Emission in Photodynamic Therapy

Chu Xuan Jin and Rui Xin Jin

MSF, 2022, 1058, 79
DOI: 10.4028/p-6bp3c4

Cancer-Cell-Activated Photodynamic Therapy Assisted by Cu(II)-Based Metal–Organic Framework

Yuanbo Wang, Wenbo Wu, Jingjing Liu, Purnima Naresh Manghnani, Fang Hu, Dou Ma, Cathleen Teh, Bo Wang and Bin Liu

ACS Nano, 2019, 13, 6879
DOI: 10.1021/acsnano.9b01665

In Vivo Three‐Photon Imaging of Lipids using Ultrabright Fluorogens with Aggregation‐Induced Emission

Shaowei Wang, Xueqi Li, Suet Yen Chong, Xiaoyuan Wang, Huan Chen, Chengjian Chen, Lai Guan Ng, Jiong‐Wei Wang and Bin Liu

Advanced Materials, 2021, 33
DOI: 10.1002/adma.202007490

Anthracene-Bridged Photosensitizers for Effective and Safe Photodynamic Therapy

Jucai Gao, Hui Yang, Yaru Lu, Qiankun Shi, Shidang Xu, Wenbo Wu, Fang Hu and Bin Liu

Chem. Mater., 2023, 35, 1229
DOI: 10.1021/acs.chemmater.2c03274

Fabricating D-A type AIE luminogen into film sensor for turn-on detection of methanol vapour

Ruixue Zhao, Mengyao Zhang, Yang Liu, Xunxue Zhang, Yuai Duan and Tianyu Han

Sensors and Actuators B: Chemical, 2020, 319, 128323
DOI: 10.1016/j.snb.2020.128323

AIE-based luminescence probes for metal ion detection

Parvej Alam, Nelson L.C. Leung, Jing Zhang, Ryan T.K. Kwok, Jacky W.Y. Lam and Ben Zhong Tang

Coordination Chemistry Reviews, 2021, 429, 213693
DOI: 10.1016/j.ccr.2020.213693

Specific discrimination of gram-positive bacteria and direct visualization of its infection towards mammalian cells by a DPAN-based AIEgen

Rong Hu, Fan Zhou, Taotao Zhou, Jianlei Shen, Zhiming Wang, Zujin Zhao, Anjun Qin and Ben Zhong Tang

Biomaterials, 2018, 187, 47
DOI: 10.1016/j.biomaterials.2018.09.019

High-Performance Conjugated Polymer Photosensitizers

Wenbo Wu

Chem, 2018, 4, 1762
DOI: 10.1016/j.chempr.2018.07.017

Cationization-Enhanced Type I and Type II ROS Generation for Photodynamic Treatment of Drug-Resistant Bacteria

Shanshan Liu, Bingnan Wang, Yuewen Yu, Yubo Liu, Zeyan Zhuang, Zujin Zhao, Guangxue Feng, Anjun Qin and Ben Zhong Tang

ACS Nano, 2022, 16, 9130
DOI: 10.1021/acsnano.2c01206

Enhancing the Theranostic Performance of Organic Photosensitizers with Aggregation-Induced Emission

Kenry and Bin Liu

Acc. Mater. Res., 2022, 3, 721
DOI: 10.1021/accountsmr.2c00039

Construction of heteroaryl-bridged NIR AIEgens for specific imaging of lipid droplets and its application in photodynamic therapy

Zhanguo Sun, Shuman Shi, Pengli Guan and Bin Liu

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 272, 120946
DOI: 10.1016/j.saa.2022.120946

Tuning Organelle Specificity and Photodynamic Therapy Efficiency by Molecular Function Design

Zhiyang Liu, Hang Zou, Zheng Zhao, Pengfei Zhang, Guo-Gang Shan, Ryan T. K. Kwok, Jacky W. Y. Lam, Lei Zheng and Ben Zhong Tang

ACS Nano, 2019, 13, 11283
DOI: 10.1021/acsnano.9b04430

Recent advances of luminogens with aggregation-induced emission in multi-photon theranostics

Miaozhuang Fan, Zhourui Xu, Maixian Liu, Yihang Jiang, Xiaomin Zheng, Chengbin Yang, Wing-Cheung Law, Ming Ying, Xiaomei Wang, Yonghong Shao, Mark T. Swihart, Gaixia Xu, Ken-Tye Yong and Ben Zhong Tang

Applied Physics Reviews, 2021, 8
DOI: 10.1063/5.0071142

AIE-Active Photosensitizer APT NPs with Type I/II ROS Generating Orchestrate the DDIT4-Centric Gene-Metabolite Axis in Photodynamic Therapy

Zhen Fang, Mei Li, Yali Mai, Wenlong Luo, Ergang Wang, Xinchun Liu, Chengyong Yang, Zhongqing Shen and Yanshan Liu

ACS Appl. Mater. Interfaces, 2025, 17, 70497
DOI: 10.1021/acsami.5c19205

Microneedle Device Delivering Aggregation-Induced Emission Photosensitizers for Enhanced Metronomic Photodynamic Therapy of Cancer

Jun Dai, Simin Wei, Jiarong Xu, Huiying Xue, Zhaojun Chen, Meng Wu, Wei Chen, Xiaoding Lou, Fan Xia and Shixuan Wang

ACS Appl. Mater. Interfaces, 2023, 15, 16526
DOI: 10.1021/acsami.3c01682

Recent molecular design strategies for efficient photodynamic therapy and its synergistic therapy based on AIE photosensitizers

Jinxi Liu, Wenting Chen, Caiyun Zheng, Fangfang Hu, Jiabao Zhai, Que Bai, Na Sun, Gao Qian, Yanni Zhang, Kai Dong and Tingli Lu

European Journal of Medicinal Chemistry, 2022, 244, 114843
DOI: 10.1016/j.ejmech.2022.114843

Light‐Induced Self‐Escape of Spherical Nucleic Acid from Endo/Lysosome for Efficient Non‐Cationic Gene Delivery

Leilei Shi, Wenbo Wu, Yukun Duan, Li Xu, Yingying Xu, Lidan Hou, Xiangjun Meng, Xinyuan Zhu and Bin Liu

Angew Chem Int Ed, 2020, 59, 19168
DOI: 10.1002/anie.202006890

Rationally designed monoamine oxidase A‐activatable AIE molecular photosensitizer for the specific imaging and cellular therapy of tumors

Yingcai Hu, Sheng‐Yan Yin, Wei Liu, Zuhao Li, Yun Chen and Jishan Li

Aggregate, 2023, 4
DOI: 10.1002/agt2.256

A specific aggregation-induced emission-conjugated polymer enables visual monitoring of osteogenic differentiation

Zhenyu Zheng, Taotao Zhou, Rong Hu, Minjun Huang, Xiang Ao, Jun Chu, Tao Jiang, Anjun Qin and Zhongmin Zhang

Bioactive Materials, 2020, 5, 1018
DOI: 10.1016/j.bioactmat.2020.06.020

Recent Advances in AIEgen‐Based Photodynamic Therapy and Immunotherapy

Menglei Zha, Guang Yang, Yaxi Li, Chen Zhang, Bo Li and Kai Li

Adv Healthcare Materials, 2021, 10
DOI: 10.1002/adhm.202101066

Rational Design of AIE Photosensitizers with Full‐Visible Color Emission and Efficient ROS Generation

Weidong Yin, Yucheng Ma, Shuge Chen, Longjiang Xing, Shaomin Ji, Jacky W. Y. Lam, Ryan T. K. Kwok, Yanping Huo and Ben Zhong Tang

Advanced Optical Materials, 2024, 12
DOI: 10.1002/adom.202302197

Biology-Oriented Design Strategies of AIE Theranostic Probes

Duo Mao and Bin Liu

Matter, 2021, 4, 350
DOI: 10.1016/j.matt.2020.12.006

Tunning Intermolecular Interaction of Peptide-Conjugated AIEgen in Nano-Confined Space for Quantitative Detection of Tumor Marker Secreted from Cells

Feng Wu, Yu Huang, Xian Yang, Jing-Jing Hu, Xiaoding Lou, Fan Xia, Yanlin Song and Lei Jiang

Anal. Chem., 2021, 93, 16257
DOI: 10.1021/acs.analchem.1c04422

Reactivity-Based Organic Theranostic Bioprobes

Kenry, Kok Chan Chong and Bin Liu

Acc. Chem. Res., 2019, 52, 3051
DOI: 10.1021/acs.accounts.9b00356

Confining Carbon Dots in Porous Wood: The Singlet Oxygen Enhancement Strategy for Photothermal Signal-Amplified Detection of Mn2+

Junxia Su, Siyu Lu, Jun Hai, Kun Liang, Tianrong Li, Shihao Sun, Fengjuan Chen, Zhengyin Yang and Baodui Wang

ACS Sustainable Chem. Eng., 2020, 8, 17687
DOI: 10.1021/acssuschemeng.0c05352

Recent advances in biomedical applications of organic fluorescence materials with reduced singlet–triplet energy gaps

Van-Nghia Nguyen, Ajay Kumar, Min Hyung Lee and Juyoung Yoon

Coordination Chemistry Reviews, 2020, 425, 213545
DOI: 10.1016/j.ccr.2020.213545

A novel AIE active NIR fluorophore based triphenylamine for sensing of Hg2+ and CN− and its multiple application

Xiaoye Wen, Li Yan and Zhefeng Fan

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 241, 118664
DOI: 10.1016/j.saa.2020.118664

Self-Improving Photosensitizer Discovery System via Bayesian Search with First-Principle Simulations

Shidang Xu, Jiali Li, Pengfei Cai, Xiaoli Liu, Bin Liu and Xiaonan Wang

J. Am. Chem. Soc., 2021, 143, 19769
DOI: 10.1021/jacs.1c08211

Metabolizable Photosensitizer with Aggregation-Induced Emission for Photodynamic Therapy

Wenbo Wu, Leilei Shi, Yukun Duan, Shidang Xu, Xihui Gao, Xinyuan Zhu and Bin Liu

Chem. Mater., 2021, 33, 5974
DOI: 10.1021/acs.chemmater.1c01173

Long-Wavelength AIE-Based Fluorescent Probes for Mitochondria-Targeted Imaging and Photodynamic Therapy of Hepatoma Cells

Dan Zhao, Hai-Hao Han, Ling Zhu, Fang-Zhou Xu, Xing-Yu Ma, Jia Li, Tony D. James, Yi Zang, Xiao-Peng He and Chengyun Wang

ACS Appl. Bio Mater., 2021, 4, 7016
DOI: 10.1021/acsabm.1c00673

Optically Active Nanomaterials for Bioimaging and Targeted Therapy

Yu Yang, Li Wang, Bin Wan, Yuxin Gu and Xinxin Li

Front. Bioeng. Biotechnol., 2019, 7
DOI: 10.3389/fbioe.2019.00320

An “all in one” strategy to boost antibacterial phototherapy via porphyrin and boron dipyrromethenes based covalent organic framework

Shao–Shuai Zhao, Xue-Ping Guo, Xiao-Hong Pan, Yuan–Biao Huang and Rong Cao

Chemical Engineering Journal, 2023, 457, 141017
DOI: 10.1016/j.cej.2022.141017