Issue 15, 2024

Sample preparation and detection methods in point-of-care devices towards future at-home testing

Abstract

Timely and accurate diagnosis is critical for effective healthcare, yet nearly half the global population lacks access to basic diagnostics. Point-of-care (POC) testing offers partial solutions by enabling low-cost, rapid diagnosis at the patient's location. At-home POC devices have the potential to advance preventive care and early disease detection. Nevertheless, effective sample preparation and detection methods are essential for accurate results. This review surveys recent advances in sample preparation and detection methods at POC. The goal is to provide an in-depth understanding of how these technologies can enhance at-home POC devices. Lateral flow assays, nucleic acid tests, and virus detection methods are at the forefront of POC diagnostic technology, offering rapid and sensitive tools for identifying and measuring pathogens, biomarkers, and viral infections. By illuminating cutting-edge research on assay development for POC diagnostics, this review aims to accelerate progress towards widely available, user-friendly, at-home health monitoring tools that empower individuals in personalized healthcare in the future.

Graphical abstract: Sample preparation and detection methods in point-of-care devices towards future at-home testing

Article information

Article type
Critical Review
Submitted
02 নভে. 2023
Accepted
24 জুন 2024
First published
02 জুলাই 2024

Lab Chip, 2024,24, 3626-3650

Sample preparation and detection methods in point-of-care devices towards future at-home testing

G. Adedokun, M. Alipanah and Z. H. Fan, Lab Chip, 2024, 24, 3626 DOI: 10.1039/D3LC00943B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements