Issue 3, 2023

Photo-induced redox cascade reaction of nitroarenes and amines

Abstract

Reduction of nitroarenes constitutes an important route to high value-added products. It is highly desirable but remains a challenge that this process occurs with selectivity under mild conditions. In this work, we developed a photochemical strategy for the mild and selective reduction of nitroarenes using amines as the reducing agent. Furthermore, the photo-induced redox reaction between nitroarenes and amines triggers a cascade process, forming isoxazolidine derivatives with high efficiency. This important skeleton was previously synthesized via the use of unstable aldehydes and hydroxylamine, which not only limits the introduction of functional groups but also complicates practical operation. This work provides an efficient way for the construction of isoxazolidine derivatives, and opens up new opportunities for the application of the photoactivation of nitroarenes and amines.

Graphical abstract: Photo-induced redox cascade reaction of nitroarenes and amines

Supplementary files

Article information

Article type
Research Article
Submitted
02 নভে. 2022
Accepted
16 ডিসে. 2022
First published
17 ডিসে. 2022

Org. Chem. Front., 2023,10, 624-631

Photo-induced redox cascade reaction of nitroarenes and amines

X. Shao, G. Xu, W. Fan, S. Zhang and M. Li, Org. Chem. Front., 2023, 10, 624 DOI: 10.1039/D2QO01743A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements