Issue 17, 2019

Facile synthesis of mixed O, S or Se bearing hexasubstituted benzenes and their potential as Cu(ii) ion probe

Abstract

The present study offers a facile route for the synthesis of unsymmetrical hexasubstituted benzenes bearing alternate heteroatoms (O, S and Se) with the formula [1,3,5-(RSeCH2)3-2,4,6-(R′ECH2)3C6] (E = O, S or Se). The synthetic protocol involves the use of an in situ generated tris(selenonium) ion followed by treatment with another nucleophile affording the targeted species in >70% yields. The unsymmetrical hexasubstituted derivatives were characterized on the basis of physicochemical and spectroscopic data and in a representative case with single crystal X-ray study. The current work assumes great significance as the potential of these species as “turn-off” chemical sensors for Cu2+, which is a biologically and environmentally crucial metal ion, was also successfully demonstrated by 5a which bears alternate oxygen and selenium centres.

Graphical abstract: Facile synthesis of mixed O, S or Se bearing hexasubstituted benzenes and their potential as Cu(ii) ion probe

Supplementary files

Article information

Article type
Paper
Submitted
31 জানু. 2019
Accepted
26 মার্চ 2019
First published
27 মার্চ 2019

Dalton Trans., 2019,48, 5627-5636

Facile synthesis of mixed O, S or Se bearing hexasubstituted benzenes and their potential as Cu(II) ion probe

A. Kumar, M. K. Yadav, J. Singh, J. D. Singh and R. J. Butcher, Dalton Trans., 2019, 48, 5627 DOI: 10.1039/C9DT00465C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements