Issue 14, 2019
From the journal:

Organic Chemistry Frontiers

Bistrifluoromethylated organocuprate [Ph4P]+[Cu(CF3)2]−: synthesis, characterization and its application for trifluoromethylation of activated heteroaryl bromides, chlorides and iodides†

He Liua  and  Qilong Shen ORCID logo *a  

* Corresponding authors

a Key Laboratory of Organofluorine Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, P. R. China
E-mail: shenql@sioc.ac.cn

Abstract

The synthesis and characterization of a bistrifluoromethylated organocuprate [Ph4P]+[Cu(CF3)2]− and its reactions with a variety of activated heteroaryl bromides, chlorides and iodides were described. These results showed that complex [Ph4P]+[Cu(CF3)2]− can serve as a trifluoromethylating reagent.

Graphical abstract: Bistrifluoromethylated organocuprate [Ph4P]+[Cu(CF3)2]−: synthesis, characterization and its application for trifluoromethylation of activated heteroaryl bromides, chlorides and iodides

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C9QO00527G
Article type
Research Article
Submitted
18 এপ্রিল 2019
Accepted
11 মে 2019
First published
13 মে 2019

Org. Chem. Front., 2019,6, 2324-2328

Permissions

Request permissions

Bistrifluoromethylated organocuprate [Ph4P]+[Cu(CF3)2]−: synthesis, characterization and its application for trifluoromethylation of activated heteroaryl bromides, chlorides and iodides

H. Liu and Q. Shen, Org. Chem. Front., 2019, 6, 2324 DOI: 10.1039/C9QO00527G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements