Themed collection Frontiers in Stimuli-Responsive Nanoplatforms: Pioneering Drug Delivery in Nanobiotechnology
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Frontiers in stimuli-responsive nanoplatforms: pioneering drug delivery in nanobiotechnology
Prof. Juan C. Cruz and Prof. Luis H. Reyes introduce the Nanoscale Advances themed issue on Frontiers in Stimuli-Responsive Nanoplatforms: Pioneering Drug Delivery in Nanobiotechnology.
Nanoscale Adv., 2024,6, 4272-4274
https://doi.org/10.1039/D4NA90074J
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Strategies for enhanced gene delivery to the central nervous system
Biological barriers in the central nervous system.
Nanoscale Adv., 2024,6, 3009-3028
https://doi.org/10.1039/D3NA01125A
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Dual-color core–shell silica nanosystems for advanced super-resolution biomedical imaging
Tailored synthesis and biotin-functionalization of dual-colored SiO2 nanoparticles as tools for advanced super-resolution microscopy imagining in biomedical approaches.
Nanoscale Adv., 2023,5, 5766-5773
https://doi.org/10.1039/D3NA00310H
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Unraveling the impact of different liposomal formulations on the plasma protein corona composition might give hints on the targeting capability of nanoparticles
Investigating complex patterns in the plasma protein corona of different liposomal formulations to identify formulation-specific protein clusters which in turn may suggest possible targeting capability.
Nanoscale Adv., 2024,6, 4434-4449
https://doi.org/10.1039/D4NA00345D
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Long-term in vivo dissolution of thermo- and pH-responsive, 19F magnetic resonance-traceable and injectable polymer implants
Thermo- and pH-responsive polymers' dissolution in vivo can be broadly fine-tuned. Polymeric implant can be detected in vivo using “hot-spot” 19F MR measurement. Long-term in vivo dissolution of polymeric implant shows no side effects.
Nanoscale Adv., 2024,6, 3041-3051
https://doi.org/10.1039/D4NA00212A
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In vitro profiling and molecular dynamics simulation studies of berberine loaded MCM-41 mesoporous silica nanoparticles to prevent neuronal apoptosis
Berberine-loaded mesoporous silica nanoparticle-controlled drug release by a simple or quasi-diffusion mechanism, improving neuronal health, preventing apoptosis, and restoring mitochondrial membrane potential.
Nanoscale Adv., 2024,6, 2469-2486
https://doi.org/10.1039/D3NA01142A
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Probing the pH-dependency of DC-SIGN/R multivalent lectin–glycan interactions using polyvalent glycan-gold nanoparticles
DC-SIGN displays distinct pH-dependent binding with GNP-DiMan, strong tetravalent binding to single GNP-DiMan at pH 7.4, weak crosslinking at pH 5.4, and no apparent binding at pH 4.6, consistent with its biological role as an endocytic recycling receptor.
Nanoscale Adv., 2024,6, 2198-2208
https://doi.org/10.1039/D3NA01013A
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Bioelectrochemically triggered apoferritin-based bionanoreactors: synthesis of CdSe nanoparticles and monitoring with leaky waveguides
Enzymatic processes, specifically laccase (Lac) catalysis, control molecular or nanomaterial synthesis within apoferritin by inducing a local pH change. Leaky waveguides technique is used for real-time monitoring of CdSe nanoparticles synthesis.
Nanoscale Adv., 2024,6, 516-523
https://doi.org/10.1039/D3NA01046E
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A new vision of photothermal therapy assisted with gold nanorods for the treatment of mammary cancers in adult female rats
Graphical abstract showing the whole photothermal process assisted with gold nanoparticles in female rats.
Nanoscale Adv., 2024,6, 170-187
https://doi.org/10.1039/D3NA00595J
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Surfactant-driven optimization of iron-based nanoparticle synthesis: a study on magnetic hyperthermia and endothelial cell uptake
This work examines the effect of changing the ratio of different surfactants in single-core iron-based nanoparticles in the context of magnetic hyperthermia and cellular uptake by human umbilical vein endothelial cells.
Nanoscale Adv., 2023,5, 5859-5869
https://doi.org/10.1039/D3NA00540B
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Synthesis of a light-responsive platinum curcumin complex, chemical and biological investigations and delivery to tumor cells by means of polymeric nanoparticles
The combination of chemical synthesis and nanotechnology led to the creation of a powerful multifunctional drug delivery system for a new platinum curcumin complex.
Nanoscale Adv., 2023,5, 5340-5351
https://doi.org/10.1039/D3NA00200D
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Light-initiated aggregation of gold nanoparticles for synergistic chemo-photothermal tumor therapy
The combination of chemotherapy with photothermal therapy (PTT) has attracted extensive attention due to its excellent synergetic effect attributing to the fact that hyperthermia can effectively promote the tumor uptake of chemotherapeutic drugs.
Nanoscale Adv., 2023,5, 3053-3062
https://doi.org/10.1039/D3NA00114H
About this collection
Guest Edited by Prof. Juan C. Cruz and Prof. Luis H. Reyes (Universidad de los Andes, Colombia). This collection focuses on the recent developments and novel approaches in stimuli-responsive nanoplatforms for drug delivery. Papers highlight the design, synthesis, and application of these nanoplatforms, with an emphasis on their potential to transform therapeutic delivery methods. We aim to highlight the intersection of nanobiotechnology and drug delivery, fostering discussions on future trends and challenges within this exciting field.