Plum-derived exosome-like nanovesicles alleviate DSS-induced colitis through gut and liver protection

Hayeon Jang, Hyun-Jin Kim, Jae-Hee Kwon, Ji-Su Kim, Dong-ha Kim, Sang-Hoon Lee, Seung-Hwan Heo, Bum-Joon Koo, Jihoon Kim, Wan-Kyu Lee, Kwang-Won Seo, Do-Kyun Kim and Young-Eun Cho

Food Funct., 2026, 17, 2599
DOI: 10.1039/D5FO04597E

Stability Challenges and Engineering Strategies of Plant-Derived Extracellular Vesicle-Like Particles: A Translational Perspective

Hengyi Li, Yuxiang Yan, Meifang Lin, Shijie Wang, Yating Su, Jinhan Guo, Youguang Lu, Xiaohang Chen and Dali Zheng

IJN, 2026, Volume 21, 1
DOI: 10.2147/IJN.S543674

Aloe vera―An Extensive Review Focused on Recent Studies

Alessia Catalano, Jessica Ceramella, Domenico Iacopetta, Maria Marra, Filomena Conforti, Francesca R. Lupi, Domenico Gabriele, Fernanda Borges and Maria Stefania Sinicropi

Foods, 2024, 13, 2155
DOI: 10.3390/foods13132155

Intestinal protective effects and mechanisms of finger citron essential oil in dextran sulfate sodium-induced ulcerative colitis mice model

Junyun Luo, Niang Tang, Chenghai Peng, Qun Wang, Shuxi Chen and Aimei Zhou

Journal of Functional Foods, 2025, 131, 106961
DOI: 10.1016/j.jff.2025.106961

Plant-derived nanovesicles: harnessing nature's power for tissue protection and repair

Xiaohang Chen, Xiaojie Xing, Shuoqi Lin, Liyu Huang, Lianghang He, Yuchun Zou, Xuyang Zhang, Bohua Su, Youguang Lu and Dali Zheng

J Nanobiotechnol, 2023, 21
DOI: 10.1186/s12951-023-02193-7

Plant-Derived Exosome-Like Nanovesicles: A Novel Strategy for Targeted Oral Therapy in Ulcerative Colitis

Hang Ning, Xinyu Huang, Na Deng, Xiaoyuan Lin, Ling Zheng, Ying Zhu and Yin Xu

IJN, 2025, Volume 20, 10595
DOI: 10.2147/IJN.S536056

Natural products-integrated drug delivery systems as innovative therapeutic strategies for inflammatory bowel disease management

Jinyan Song, Tao Wang, Kunlong Zhang, Pengfei Zhu, Yi Yu, Tao Li, Deyan Gong, Lisha Zha and Yan Ma

Nano Research, 2025, 18, 94908007
DOI: 10.26599/NR.2025.94908007

Therapeutic Effect of Membrane Vesicle Drug Delivery Systems in Inflammatory Bowel Disease

Zhe Zhao, Ziyun Li, Yihuang Gu and Renjun Gu

Pharmaceutics, 2025, 17, 1127
DOI: 10.3390/pharmaceutics17091127

Plant-derived nanovesicles and therapeutic application

Dokyung Jung, Na-Eun Kim, Sua Kim, Ju-Hyun Bae, Il-Young Jung, Kyung-Won Doh, Byungheon Lee, Do-Kyun Kim, Young-Eun Cho and Moon-Chang Baek

Pharmacology & Therapeutics, 2025, 269, 108832
DOI: 10.1016/j.pharmthera.2025.108832

Undaria pinnatifida-derived nanovesicles regulate bone remodeling by stimulating osteoblast differentiation and suppressing osteoclast formation

Seung-Hwan Heo, Sang-Hoon Lee, Bum-Joon Koo, Jae-Hee Kwon, Hayeon Jang, Jihoon Kim, Do-Kyun Kim and Young-Eun Cho

Journal of Functional Foods, 2026, 139, 107233
DOI: 10.1016/j.jff.2026.107233

Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

Ying‐qi Cao, Zheng‐ting Wu, Qi You, Yuan‐yuan Xia, Qing Zhao, Carine de Marcos Lousa and Ke‐wei Zhao

Interdisciplinary Medicine, 2025, 3
DOI: 10.1002/INMD.20250038

Osteogenic Effects of Brown Algae Sargassum fulvellum-Derived Exosome-Like Nanovesicles via the BMP-2/4-MAPK-Smad1/5/8 Signaling Pathway

Bum-Joon Koo, Dong-ha Kim, Sang-Hoon Lee, Jae-Hee Kwon, Hayeon Jang, Seung-Hwan Heo, Dong-Hwan Yoon, Do-Kyung Lim, Sun-Mee Hong and Young-Eun Cho

Prev. Nutr. Food Sci., 2025, 30, 557
DOI: 10.3746/pnf.2025.30.6.557

Therapeutic application and potential mechanism of plant-derived extracellular vesicles in inflammatory bowel disease

Jinling Li, Ting Luo, Dou Wang, Yao Zhao, Yuanxiang Jin, Guiling Yang and Xin Zhang

Journal of Advanced Research, 2025, 68, 63
DOI: 10.1016/j.jare.2024.01.035

Colon‐adhesive poly(maleic anhydride)‐sirolimus conjugate alleviates local colitis inflammation

Sang‐Hun Choi, Soo‐Hyang Chi, Yu‐Seong Park, Sejin Son, Young‐Eun Cho and Jihoon Kim

J of Applied Polymer Sci, 2024, 141
DOI: 10.1002/app.56220

Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trends

Hong-Yu Jiang, Bo Shao, Hong-Da Wang, Wen-Qi Zhao, Shao-Hua Ren, Yi-Ni Xu, Tong Liu, Cheng-Lu Sun, Yi-Yi Xiao, Yi-Cheng Li, Qiang Chen, Peng-Yu Zhao, Guang-Mei Yang, Xu Liu, Yu-Fan Ren and Hao Wang

Front. Pharmacol., 2025, 15
DOI: 10.3389/fphar.2024.1523052

Utility of edible plant-derived exosome-like nanovesicles as a novel delivery platform for vaccine antigen delivery

Hyun-Jin Kim, Sang-Hoon Lee, Yu-Seong Park, Dong-Won Seo, Kwang-Won Seo, Do-Kyun Kim, Yo Han Jang, Jae-Hwan Lim and Young-Eun Cho

Vaccine, 2025, 52, 126902
DOI: 10.1016/j.vaccine.2025.126902

The effects of antimicrobial peptide-chitosan nanoparticles on alleviating ulcerative colitis in Citrobacter rodentium infected mice

Yinfeng Lyu, Yang Yang, Peiyang Li, Chuqiao Zhou, Licong Zhang, Chongpeng Bi and Anshan Shan

Food Bioscience, 2025, 68, 106575
DOI: 10.1016/j.fbio.2025.106575

Emerging Role of Plant-Derived Nanostructures in Nanomedicine

Huijie Xing, Guichan Li, Chunli Qi, Ming Zhang, Ning Ding and Xingwang Zhang

IJN, 2025, Volume 20, 12715
DOI: 10.2147/IJN.S547550

Plant-Derived Exosome-Like Nanovesicles in Chronic Wound Healing

Weiquan Wu, Bing Zhang, Weiqi Wang, Qiujin Bu, Yuange Li, Peihua Zhang and Li Zeng

IJN, 2024, Volume 19, 11293
DOI: 10.2147/IJN.S485441

The anti-cancer effect of pomegranate-derived nanovesicles on MDA-MB-231 breast cancer cells

Dong-ha Kim, Ji-Su Kim, In-Sook Kwun and Young-Eun Cho

J Nutr Health, 2024, 57, 43
DOI: 10.4163/jnh.2024.57.1.43

Plant extracellular vesicles: A promising bionic medicine platform for disease treatment and drug delivery

Jichun Yang, Yuhan Wang, Yunqian Fu, Sitong Wang, Yao Luo, Xin Cui, Chenyu Sun, Jianing Ji, Jiaxi Mo, Yang Wang, Yilin Liu, Xinghong Hu, Xiaohui Chen, Yimin Jia and Yang Luo

Interdisciplinary Medicine, 2025, 3
DOI: 10.1002/INMD.20240101

Exploring the impact of dietary extracellular vesicles on gut health: homeostasis, barrier defense, immunity, and signaling pathways

Haiyan Zhang, Jianing Tu, Yue Pang, Jiahui Ma, Lin Zhang, Chenyu Xue, Yuhao Liu, Weichen Hong, Mizhou Hui, Bailiang Li, Na Dong and Chenzhe Gao

Food Research International, 2026, 230, 118515
DOI: 10.1016/j.foodres.2026.118515

Healing the Gut Naturally: Exploring Herbal Remedies for Functional Gastrointestinal Disorders

Antra Sinha, Saumya Das and Avijit Mazumder

JNR, 2025, 1575
DOI: 10.18311/jnr/2025/49575

Therapeutic potential of panax ginseng-derived nanovesicles in osteoporosis through enhanced osteoblast

Sang-Hoon Lee, Jae-Hee Kwon, Hyun-Woo Kim, Se Hwan Mun, Young Yang, Jihoon Kim, Kwang-Won Seo, Do-Kyun Kim and Young-Eun Cho

Journal of Ginseng Research, 2026, 101016
DOI: 10.1016/j.jgr.2026.101016

Biogenesis, preparation, characterization, therapeutic mechanisms and safety evaluation of plant-derived exosome-like nanovesicles in the treatment of ulcerative colitis

Cailan Li, Luyou Zhao, Xuefei Wang, Jingjing Wu, Haohui Chen and Qiang Lu

J Nanobiotechnol, 2026
DOI: 10.1186/s12951-026-04209-4

Traditional Chinese Medicine formulas-based interventions on colorectal carcinoma prevention: The efficacies, mechanisms and advantages

Xiaojuan Tang, Min He, Yuan Ren, Meng Ji, Xiaoqi Yan, Wen Zeng, Yuan Lv, Yongmin Li and Yongheng He

Journal of Ethnopharmacology, 2025, 337, 119008
DOI: 10.1016/j.jep.2024.119008

Current Research on Aloe-Derived Extracellular Vesicles in Injury Repair

Yuqing Mu and Han Zhang

IJN, 2026, Volume 21, 1
DOI: 10.2147/IJN.S584266