Research progress related to thermosensitive hydrogel dressings in wound healing: a review

Ruting Gu, Haiqing Zhou, Zirui Zhang, Yun Lv, Yueshuai Pan, Qianqian Li, Changfang Shi, Yanhui Wang and Lili Wei

Nanoscale Adv., 2023, 5, 6017
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Glycopolymer-based multifunctional antibacterial hydrogel dressings for accelerating cutaneous wound healing

Qiuli Cheng, Zhihao Wang, Shumin Hu, Yi-Yang Peng, Rui Zhu, Leitao Zhang, Junbo Li and Ravin Narain

J. Mater. Chem. B, 2023, 11, 7228
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Antimicrobial peptide hydrogels: synthesis, ROS regulation mechanism, and multimodal therapeutic applications in drug delivery systems

Dingjun Cai, Canhong Li, Taifu Zhu, Ruiqi Li, Mu Zhang, Xiaoling Li, Yilong Liu, Zhifei Dai, Lei Wan and Haibin Lu

J. Mater. Chem. B, 2025, 13, 14556
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Self-assembled nanostructured antimicrobial peptides: design strategies, structures, mechanism and therapeutic applications

Zishu Wang, XianXi Li, Huijing Chen, Jiawei Du, Liangxiao Huang, Tongxuan Xin, Meigui Ma, Wufu Zhu, Pengwu Zheng, Cunpeng Nie and Qingshan Pan

J. Mater. Chem. B, 2025, 13, 14593
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Current status of development and biomedical applications of peptide-based antimicrobial hydrogels

Huihui Qu, Quanfu Yao, Ting Chen, Haixia Wu, Ying Liu, Cong Wang and Alideertu Dong

Advances in Colloid and Interface Science, 2024, 325, 103099
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Biomaterials releasing drug responsively to promote wound healing via regulation of pathological microenvironment

Haisheng Li, Buying Li, Dalun Lv, Wenhong Li, Yifei Lu and Gaoxing Luo

Advanced Drug Delivery Reviews, 2023, 196, 114778
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Molecular-Level Design Principles and Strategies of Peptide Self-Assembly Nanomaterials: From Sequence Engineering to Functional Applications

Ying Luo, Xian Liu, Zhan Dong and Yuzhu Song

IJN, 2025, Volume 20, 15277
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Antibacterial smart hydrogels: New hope for infectious wound management

Zahra Aliakbar Ahovan, Zahra Esmaeili, Behnaz Sadat Eftekhari, Sadjad Khosravimelal, Morteza Alehosseini, Gorka Orive, Alireza Dolatshahi-Pirouz, Narendra Pal Singh Chauhan, Paul A. Janmey, Ali Hashemi, Subhas C. Kundu and Mazaher Gholipourmalekabadi

Materials Today Bio, 2022, 17, 100499
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Functional Peptide-Based Biomaterials for Pharmaceutical Application: Sequences, Mechanisms, and Optimization Strategies

Dedong Yu, Nari Han, Hyejeong Son, Sun Jo Kim and Seho Kweon

JFB, 2026, 17, 37
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Recent Advances in Antimicrobial Peptide Hydrogels

Aryanna Copling, Maxwell Akantibila, Raaha Kumaresan, Gilbert Fleischer, Dennise Cortes, Rahul S. Tripathi, Valerie J. Carabetta and Sebastián L. Vega

IJMS, 2023, 24, 7563
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Advances of Antimicrobial Peptide‐Based Biomaterials for the Treatment of Bacterial Infections

Guoyu Li, Zhenheng Lai and Anshan Shan

Advanced Science, 2023, 10
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Antimicrobial peptides as antimicrobials for wound care management: A comprehensive review

Kunal Agam Kanaujia, Nidhi Mishra, P.S. Rajinikanth and Shubhini A. Saraf

Journal of Drug Delivery Science and Technology, 2024, 95, 105570
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Efficacy of RADA16-Based Self-Assembling Peptides on Wound Healing: A Meta-Analysis of Preclinical Animal Studies

Jiaju Lu, Liuting Chen, Zeyue Sun and Zhimou Yang

Pharmaceuticals, 2025, 18, 526
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An injectable thermo-sensitive hydrogel of PNICL-PEG-PNICL block copolymer as a sustained release carrier of EGCG

Huimin Shan, Wang Yin, Lianlei Wen, Anrong Mao and Meidong Lang

European Polymer Journal, 2023, 195, 112214
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Advancing biomedicine with gel‐based materials and composites: A comprehensive review

Sara Sajjadi, Aiesheh Gholizadeh‐Hashjin, Fatemeh Shafizadeh, Sahar Marefat, Samin Hamidi and Afsaneh Farjami

J of Applied Polymer Sci, 2023, 140
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Influence of Electrostatic Interactions on the Self-Assembly of Charged Peptides

Xue Sun, Bolan Wu, Na Li, Bo Liu, Shijun Li, Liang Ma and Hangyu Zhang

Gels, 2025, 11, 80
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Mechanism of Peptide Self-assembly and Its Study in Biomedicine

Xinyue Yang, Li Ma, Kui Lu and Dongxin Zhao

Protein J, 2024, 43, 464
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Poly(ectoine)‐Based Adhesive Hydrogel with Antimicrobial and Anti‐Inflammatory Properties for Wound Treatment

Xinyue Wang, Rong Mu, Yan Zhou, Jiamin Li, Qianlong Ma, Jing Wang, Yanfei Ma, Wenbo Sheng, Xuzhi Hu, Feng Zhou and Bin Li

Adv Funct Materials, 2025, 35
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Antimicrobial Peptide Nanoassemblies: Design, Response Mechanisms, and Biomedical Applications

Tao Wang, Linbao Ji, Yucheng Zhang, Zhili Niu, Xiaoyi Jiang, Xingyao Wang, Qingtai Zhang, Yuting Zhang, Peng Tan, Yue Feng, Xi Ma and Zhihong Sun

Molecules, 2026, 31, 518
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Smart Antibiofilm Platforms Based on Synthetic Antimicrobial Peptides-Engineered Hydrogels

Carpa Rahela, Bogyor Agota-Katalin and Butiuc-Keul Anca

Polymers, 2026, 18, 471
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Preparation, properties and in vitro osteogensis of self-reinforcing injectable hydrogel

Hongyan Wu, Xunming Zhang, Zhaoguo Wang, Xi Chen, Yi Li, Jiayuan Fang, Shuo zheng, Libo Zhang, Changhong Li and Linlin Hao

European Journal of Pharmaceutical Sciences, 2024, 192, 106617
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Novel Biomaterials for Wound Healing and Tissue Regeneration

Yi Zhong, Er-ting Wei, Leran Wu, Yong Wang, Qin Lin, Nihuan Wu, Hongpeng Chen and Nan Tang

ACS Omega, 2024
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Antibacterial and antioxidant peptide hydrogel dressings with pH responsive release properties for rapid hemostasis and wound healing promotion

Leixia Mei, Zijian He, Haihong Yang, Qingjiao Mei, Shilei Ji, Yan-Qin He, Zhengping Wang and Jun Han

Journal of Drug Delivery Science and Technology, 2025, 111, 107164
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Preparation of Chitosan/DMAPMA/PVA Composite Gels and Study of Their Properties

凤钏郭

NAT, 2025, 15, 88
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Stimuli‐Responsive Delivery of Antimicrobial Peptides Using Polyelectrolyte Complexes

Alexander Antropenko, Frank Caruso and Paco Fernandez‐Trillo

Macromolecular Bioscience, 2023, 23
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Antimicrobial Hydrogels: Potential Materials for Medical Application

Yanni Li, Yujia Han, Hongxia Li, Xiaohui Niu, Deyi Zhang and Kunjie Wang

Small, 2024, 20
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Synthetic Reversible Fibrous Network Hydrogels Based on a Double‐Helical Polyelectrolyte

Haonan Zheng, Kaizheng Liu, Yongheng Cui, Legeng Li, Qinbo Liu and Yongjun Men

Angewandte Chemie, 2025, 137
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A Comprehensive Review of Thermosensitive Hydrogels: Mechanism, Optimization Strategies, and Applications

Tianyang Lv, Yuzhu Chen, Ning Li, Xiaoyu Liao, Yumin Heng, Yayuan Guo and Kaijin Hu

Gels, 2025, 11, 544
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Synthetic Reversible Fibrous Network Hydrogels Based on a Double‐Helical Polyelectrolyte

Haonan Zheng, Kaizheng Liu, Yongheng Cui, Legeng Li, Qinbo Liu and Yongjun Men

Angew Chem Int Ed, 2025, 64
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Antioxidant hydrogel from poly(aspartic acid) and carboxymethylcellulose with quercetin loading as burn wound dressing

Jingjing Zhu, Kaiyue Zhang, Yu Zhang, Chengyan Zhou, Zhe Cui, Wenjuan Li, Yong Wang and Jianglei Qin

International Journal of Biological Macromolecules, 2024, 282, 137323
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The Potential of Non-Ribosomal Peptide Engineering for Creating New Antimicrobial Complexes

Evgeniya V. Prazdnova, Maxim P. Kulikov and Ludmila E. Khmelevtsova

Molecules, 2026, 31, 683
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Self-assembling peptides: Perspectives regarding biotechnological applications and vaccine development

César Reyes and Manuel A. Patarroyo

International Journal of Biological Macromolecules, 2024, 259, 128944
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Engineered bioadhesive Self-Healing nanocomposite hydrogel to fight infection and accelerate cutaneous wound healing

Parinaz Nezhad-Mokhtari, Hamed Hamishehkar, Mohammad R Farahpour, Ahmad Mehdipour, Reza Rahbarghazi, Morteza Milani and Mehdi Mehrali

Chemical Engineering Journal, 2024, 489, 150992
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Multifunctional and theranostic hydrogels for wound healing acceleration: An emphasis on diabetic-related chronic wounds

Pooya M. Tehrany, Parham Rahmanian, Aryan Rezaee, Golnaz Ranjbarpazuki, Farima Sohrabi Fard, Yasaman Asadollah salmanpour, Mohammad Arad Zandieh, Ali Ranjbarpazuki, Sajedeh Asghari, Nazanin Javani, Noushin Nabavi, Amir Reza Aref, Mehrdad Hashemi, Mohsen Rashidi, Afshin Taheriazam, Alireza Motahari and Kiavash Hushmandi

Environmental Research, 2023, 238, 117087
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Double Cross‐Linked Biomimetic Hyaluronic Acid‐Based Hydrogels with Thermo‐Stimulated Self‐Contraction and Tissue Adhesiveness for Accelerating Post‐Wound Closure and Wound Healing

Yaodong Zhao, Bingcheng Yi, Jilin Hu, Dongjie Zhang, Guotai Li, Yun Lu and Qihui Zhou

Adv Funct Materials, 2023, 33
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Self-Assembled Peptide Hydrogels in Regenerative Medicine

Shuangyang Li, Qixuan Yu, Hongpeng Li, Meiqi Chen, Ye Jin and Da Liu

Gels, 2023, 9, 653
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IKVAV peptide-containing hydrogel decreases fibrous scar after spinal cord injury by inhibiting fibroblast migration and activation

Tao Jiang, Shitong Li, Benchang Xu, Kun Liu, Tong Qiu and Honglian Dai

Behavioural Brain Research, 2023, 455, 114683
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Peptide‐Based Biomaterials as a Promising Tool for Cancer Radiotherapy

Qian Wang, Xinhui Chu and Jianfeng Liu

Advanced Science, 2025, 12
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Self-Assembling Peptide RADA16: A Promising Scaffold for Tissue Engineering and Regenerative Medicine

Xin Yao, Yicun Hu, Maoqiang Lin, Kaichen Peng, Peng Wang, Yanbing Gao, Xidan Gao, Taowen Guo, Xiaobo Zhang and Haiyu Zhou

Nanomedicine (Lond.), 2023, 18, 1305
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Design, preparation, and characterization of injectable thermosensitive polymer-based hydrogels with enhanced mechanical properties for sustained liraglutide release

Wei-Jie Cheng, Tzu-Yi Yeh, Chih-Yu Hsieh, Hsun-Yueh Chuang, Fang-Ching Chao, Jing-Ping Liou and Chien-Ming Hsieh

Journal of Drug Delivery Science and Technology, 2025, 108, 106909
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Self-Assembled Food Peptides: Recent Advances and Perspectives in Food and Health Applications

Raliat O. Abioye, Jairo Andrés Camaño Echavarría, Joy I. Obeme-Nmom, Martha S. Yiridoe, Oluwaseyi A. Ogunrinola, Matthew D. Ezema and Chibuike C. Udenigwe

J. Agric. Food Chem., 2024, 72, 8372
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Advances in Composite Stimuli-Responsive Hydrogels for Wound Healing: Mechanisms and Applications

Ke Ding, Mingrui Liao, Yingyu Wang and Jian R. Lu

Gels, 2025, 11, 420
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Antimicrobial Peptides for Skin Wound Healing

Yifan Wu, Tingting Liu, Lili Jin, Chuyuan Wang and Dianbao Zhang

Biomolecules, 2025, 15, 1613
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Recent advances in hydrogels-based osteosarcoma therapy

Hao Tian, Ronghui Wu, Na Feng, Jinrui Zhang and Jianlin Zuo

Front. Bioeng. Biotechnol., 2022, 10
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