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Size-based microfluidic multimodal microparticle sorter
Xiao Wang and Ian Papautsky
Lab Chip, 2015, 15, 1350
DOI: 10.1039/C4LC00803K

Probing circulating tumor cells in microfluidics
Peng Li, Zackary S. Stratton, Ming Dao, Jerome Ritz and Tony Jun Huang
Lab Chip, 2013, 13, 602
DOI: 10.1039/c2lc90148j

Inertial focusing of spherical particles in rectangular microchannels over a wide range of Reynolds numbers
Chao Liu, Guoqing Hu, Xingyu Jiang and Jiashu Sun
Lab Chip, 2015, 15, 1168
DOI: 10.1039/C4LC01216J

Label-free isolation of rare tumor cells from untreated whole blood by interfacial viscoelastic microfluidics
Fei Tian, Lili Cai, Jianqiao Chang, Shanshan Li, Chao Liu, Tiejun Li and Jiashu Sun
Lab Chip, 2018, 18, 3436
DOI: 10.1039/C8LC00700D

Multiplexing slanted spiral microchannels for ultra-fast blood plasma separation
Mehdi Rafeie, Jun Zhang, Mohsen Asadnia, Weihua Li and Majid Ebrahimi Warkiani
Lab Chip, 2016, 16, 2791
DOI: 10.1039/C6LC00713A

Channel innovations for inertial microfluidics
Wenlai Tang, Shu Zhu, Di Jiang, Liya Zhu, Jiquan Yang and Nan Xiang
Lab Chip, 2020, 20, 3485
DOI: 10.1039/D0LC00714E

Optoacoustic tweezers: a programmable, localized cell concentrator based on opto-thermally generated, acoustically activated, surface bubbles
Yuliang Xie, Chenglong Zhao, Yanhui Zhao, Sixing Li, Joseph Rufo, Shikuan Yang, Feng Guo and Tony Jun Huang
Lab Chip, 2013, 13, 1772
DOI: 10.1039/c3lc00043e

Inertial microfluidic physics
Hamed Amini, Wonhee Lee and Dino Di Carlo
Lab Chip, 2014, 14, 2739
DOI: 10.1039/c4lc00128a

Inertial microfluidics: current status, challenges, and future opportunities
Nan Xiang and Zhonghua Ni
Lab Chip, 2022, 22, 4792
DOI: 10.1039/D2LC00722C

Inertial migration of polymer micelles in a square microchannel
Qingfeng Shi, Jintang Wu, Haisong Chen, Xiaolong Xu, Yong-Biao Yang and Mingming Ding
Soft Matter, 2024, 20, 1760
DOI: 10.1039/D3SM01304A

Label-free mesenchymal stem cell enrichment from bone marrow samples by inertial microfluidics
Lap Man Lee, Jenna M. Rosano, Yi Wang, George J. Klarmann, Charles J. Garson, Balabhaskar Prabhakarpandian, Kapil Pant, Luis M. Alvarez and Eva Lai
Anal. Methods, 2018, 10, 713
DOI: 10.1039/C7AY02500A

Deformability and size-based cancer cell separation using an integrated microfluidic device
Long Pang, Shaofei Shen, Chao Ma, Tongtong Ma, Rui Zhang, Chang Tian, Lei Zhao, Wenming Liu and Jinyi Wang
Analyst, 2015, 140, 7335
DOI: 10.1039/C5AN00799B

Challenges in blood fractionation for cancer liquid biopsy: how can microfluidics assist?
Robert Salomon, Sajad Razavi Bazaz, Kirk Mutafopulos, David Gallego-Ortega, Majid Warkiani, David Weitz and Dayong Jin
Lab Chip, 2025, 25, 1097
DOI: 10.1039/D4LC00563E

Size-tuneable isolation of cancer cells using stretchable inertial microfluidics
Hedieh Fallahi, Sharda Yadav, Hoang-Phuong Phan, Hang Ta, Jun Zhang and Nam-Trung Nguyen
Lab Chip, 2021, 21, 2008
DOI: 10.1039/D1LC00082A

Rapid and precise tumor cell separation using the combination of size-dependent inertial and size-independent magnetic methods
Di Huang and Nan Xiang
Lab Chip, 2021, 21, 1409
DOI: 10.1039/D0LC01223H

Enrichment, detection and clinical significance of circulating tumor cells
Sunil K. Arya, Bing Lim and Abdur Rub Abdur Rahman
Lab Chip, 2013, 13, 1995
DOI: 10.1039/c3lc00009e

An automated and portable microfluidic chemiluminescence immunoassay for quantitative detection of biomarkers
Binfeng Hu, Juanjuan Li, Lei Mou, Yong Liu, Jinqi Deng, Wei Qian, Jiashu Sun, Ruitao Cha and Xingyu Jiang
Lab Chip, 2017, 17, 2225
DOI: 10.1039/C7LC00249A

Spiral microchannel with ordered micro-obstacles for continuous and highly-efficient particle separation
Shaofei Shen, Chang Tian, Tianbao Li, Juan Xu, Shu-Wei Chen, Qin Tu, Mao-Sen Yuan, Wenming Liu and Jinyi Wang
Lab Chip, 2017, 17, 3578
DOI: 10.1039/C7LC00691H

Recent progress of particle migration in viscoelastic fluids
Dan Yuan, Qianbin Zhao, Sheng Yan, Shi-Yang Tang, Gursel Alici, Jun Zhang and Weihua Li
Lab Chip, 2018, 18, 551
DOI: 10.1039/C7LC01076A

Recent progress of inertial microfluidic-based cell separation
Xuefeng Xu, Xiwei Huang, Jingjing Sun, Renjie Wang, Jiangfan Yao, Wentao Han, Maoyu Wei, Jin Chen, Jinhong Guo, Lingling Sun and Ming Yin
Analyst, 2021, 146, 7070
DOI: 10.1039/D1AN01160J

High-throughput rare cell separation from blood samples using steric hindrance and inertial microfluidics
Shaofei Shen, Chao Ma, Lei Zhao, Yaolei Wang, Jian-Chun Wang, Juan Xu, Tianbao Li, Long Pang and Jinyi Wang
Lab Chip, 2014, 14, 2525
DOI: 10.1039/C3LC51384J

Multiplexed microfluidic blotting of proteins and nucleic acids by parallel, serpentine microchannels
Sha He, Yi Zhang, Pei Wang, Xingzhi Xu, Kui Zhu, Wenying Pan, Wenwen Liu, Kaiyong Cai, Jiashu Sun, Wei Zhang and Xingyu Jiang
Lab Chip, 2015, 15, 105
DOI: 10.1039/C4LC00901K

A generalized formula for inertial lift on a sphere in microchannels
Chao Liu, Chundong Xue, Jiashu Sun and Guoqing Hu
Lab Chip, 2016, 16, 884
DOI: 10.1039/C5LC01522G

Rapid separation of human breast cancer cells from blood using a simple spiral channel device
Di Huang, Xin Shi, Yi Qian, Wenlai Tang, Linbo Liu, Nan Xiang and Zhonghua Ni
Anal. Methods, 2016, 8, 5940
DOI: 10.1039/C6AY01077F

A high throughput microfluidic platform for size-selective enrichment of cell populations in tissue and blood samples
Nivedita Nivedita, Neha Garg, Abraham P. Lee and Ian Papautsky
Analyst, 2017, 142, 2558
DOI: 10.1039/C7AN00290D

Slanted spiral microfluidics for the ultra-fast, label-free isolation of circulating tumor cells
Majid Ebrahimi Warkiani, Guofeng Guan, Khoo Bee Luan, Wong Cheng Lee, Ali Asgar S. Bhagat, Parthiv Kant Chaudhuri, Daniel Shao-Weng Tan, Wan Teck Lim, Soo Chin Lee, Peter C. Y. Chen, Chwee Teck Lim and Jongyoon Han
Lab Chip, 2014, 14, 128
DOI: 10.1039/C3LC50617G

A microfluidic tubing method and its application for controlled synthesis of polymeric nanoparticles
Jidong Wang, Wenwen Chen, Jiashu Sun, Chao Liu, Qifang Yin, Lu Zhang, Yunlei Xianyu, Xinghua Shi, Guoqing Hu and Xingyu Jiang
Lab Chip, 2014, 14, 1673
DOI: 10.1039/C4LC00080C

A Dean-flow-coupled interfacial viscoelastic fluid for microparticle separation applied in a cell smear method
Xin Shi, Liyan Liu, Wenfeng Cao, Guorui Zhu and Wei Tan
Analyst, 2019, 144, 5934
DOI: 10.1039/C9AN01070J

High throughput extraction of plasma using a secondary flow-aided inertial microfluidic device
Jun Zhang, Sheng Yan, Weihua Li, Gursel Alici and Nam-Trung Nguyen
RSC Adv., 2014, 4, 33149
DOI: 10.1039/C4RA06513A

Reverse flow enhanced inertia pinched flow fractionation
Saijie Wang, Quanchen Xu, Zhihan Zhang, Shengbo Chen, Yizhou Jiang, Zhuowei Feng, Dou Wang and Xingyu Jiang
Lab Chip, 2023, 23, 4324
DOI: 10.1039/D3LC00473B

Technologies for label-free separation of circulating tumor cells: from historical foundations to recent developments
Chao Jin, Sarah M. McFaul, Simon P. Duffy, Xiaoyan Deng, Peyman Tavassoli, Peter C. Black and Hongshen Ma
Lab Chip, 2014, 14, 32
DOI: 10.1039/C3LC50625H

A review of enrichment methods for circulating tumor cells: from single modality to hybrid modality
Yi Zhang, Yifu Li and Zhongchao Tan
Analyst, 2021, 146, 7048
DOI: 10.1039/D1AN01422F

Tunnel dielectrophoresis for ultra-high precision size-based cell separation
Yu-Chun Kung, Kayvan R. Niazi and Pei-Yu Chiou
Lab Chip, 2021, 21, 1049
DOI: 10.1039/D0LC00853B

A simplified sheathless cell separation approach using combined gravitational-sedimentation-based prefocusing and dielectrophoretic separation
Tao Luo, Lei Fan, Yixiao Zeng, Ya Liu, Shuxun Chen, Qiulin Tan, Raymond H. W. Lam and Dong Sun
Lab Chip, 2018, 18, 1521
DOI: 10.1039/C8LC00173A

Recent advances in microfluidic technologies for circulating tumor cells: enrichment, single-cell analysis, and liquid biopsy for clinical applications
Haimeng Pei, Lu Li, Zhaojun Han, Yiguo Wang and Bo Tang
Lab Chip, 2020, 20, 3854
DOI: 10.1039/D0LC00577K

Hydraulic–electric analogy for design and operation of microfluidic systems
Zhenglin Li, Chao Liu and Jiashu Sun
Lab Chip, 2023, 23, 3311
DOI: 10.1039/D3LC00265A

Advances and critical concerns with the microfluidic enrichments of circulating tumor cells
Kyung-A Hyun and Hyo-Il Jung
Lab Chip, 2014, 14, 45
DOI: 10.1039/C3LC50582K

Size and deformability based separation of circulating tumor cells from castrate resistant prostate cancer patients using resettable cell traps
Xi Qin, Sunyoung Park, Simon P. Duffy, Kerryn Matthews, Richard R. Ang, Tilman Todenhöfer, Hamid Abdi, Arun Azad, Jenny Bazov, Kim N. Chi, Peter C. Black and Hongshen Ma
Lab Chip, 2015, 15, 2278
DOI: 10.1039/C5LC00226E

Machine learning assisted fast prediction of inertial lift in microchannels
Jinghong Su, Xiaodong Chen, Yongzheng Zhu and Guoqing Hu
Lab Chip, 2021, 21, 2544
DOI: 10.1039/D1LC00225B

A microfluidic origami chip for synthesis of functionalized polymeric nanoparticles
Jiashu Sun, Yunlei Xianyu, Mengmeng Li, Wenwen Liu, Lu Zhang, Dingbin Liu, Chao Liu, Guoqing Hu and Xingyu Jiang
Nanoscale, 2013, 5, 5262
DOI: 10.1039/c3nr01289a

Tuning particle inertial separation in sinusoidal channels by embedding periodic obstacle microstructures
Haotian Cha, Hedieh Fallahi, Yuchen Dai, Sharda Yadav, Samith Hettiarachchi, Antony McNamee, Hongjie An, Nan Xiang, Nam-Trung Nguyen and Jun Zhang
Lab Chip, 2022, 22, 2789
DOI: 10.1039/D2LC00197G

Fully-automated and field-deployable blood leukocyte separation platform using multi-dimensional double spiral (MDDS) inertial microfluidics
Hyungkook Jeon, Bakr Jundi, Kyungyong Choi, Hyunryul Ryu, Bruce D. Levy, Geunbae Lim and Jongyoon Han
Lab Chip, 2020, 20, 3612
DOI: 10.1039/D0LC00675K

Recent advances in microfluidic cell separations
Yan Gao, Wenjie Li and Dimitri Pappas
Analyst, 2013, 138, 4714
DOI: 10.1039/c3an00315a

DLD pillar shape design for efficient separation of spherical and non-spherical bioparticles
Shashi Ranjan, Kerwin Kwek Zeming, Roland Jureen, Dale Fisher and Yong Zhang
Lab Chip, 2014, 14, 4250
DOI: 10.1039/C4LC00578C

Improved understanding of particle migration modes in spiral inertial microfluidic devices
Nan Xiang, Zhiguo Shi, Wenlai Tang, Di Huang, Xinjie Zhang and Zhonghua Ni
RSC Adv., 2015, 5, 77264
DOI: 10.1039/C5RA13292D

Enhancement of inflection point focusing and rare-cell separations from untreated whole blood
Dongwoo Lee, Yo-han Choi and Wonhee Lee
Lab Chip, 2020, 20, 2861
DOI: 10.1039/D0LC00309C

A disposable, roll-to-roll hot-embossed inertial microfluidic device for size-based sorting of microbeads and cells
Xiao Wang, Christina Liedert, Ralph Liedert and Ian Papautsky
Lab Chip, 2016, 16, 1821
DOI: 10.1039/C6LC00215C

Fundamentals and applications of inertial microfluidics: a review
Jun Zhang, Sheng Yan, Dan Yuan, Gursel Alici, Nam-Trung Nguyen, Majid Ebrahimi Warkiani and Weihua Li
Lab Chip, 2016, 16, 10
DOI: 10.1039/C5LC01159K

Highly selective biomechanical separation of cancer cells from leukocytes using microfluidic ratchets and hydrodynamic concentrator
Bill K. Lin, Sarah M. McFaul, Chao Jin, Peter C. Black and Hongshen Ma
Biomicrofluidics, 2013, 7
DOI: 10.1063/1.4812688

Continuous separation of bacterial cells from large debris using a spiral microfluidic device
Ayomikun Esan, Frédérique Vanholsbeeck, Simon Swift and Cushla M. McGoverin
Biomicrofluidics, 2023, 17
DOI: 10.1063/5.0159254

Detection, manipulation and post processing of circulating tumor cells using optical techniques
Somayyeh Bakhtiaridoost, Hamidreza Habibiyan and Hassan Ghafoorifard
Mod. Phys. Lett. B, 2015, 29, 1530010
DOI: 10.1142/S0217984915300100

Numerical Simulation of a Sheathless Multi-CTC Separator Lab-on-a-Chip Using Inertial Focusing Method
Writtick Pakhira, R. Kumar and Khalid Mohd. Ibrahimi
Comp. Part. Mech., 2024, 11, 2143
DOI: 10.1007/s40571-024-00770-7

High-Throughput, Label-Free Isolation of White Blood Cells from Whole Blood Using Parallel Spiral Microchannels with U-Shaped Cross-Section
Amirhossein Mehran, Peyman Rostami, Mohammad Said Saidi, Bahar Firoozabadi and Navid Kashaninejad
Biosensors, 2021, 11, 406
DOI: 10.3390/bios11110406

Two-Way Coupling Fluid-Structure Interaction (FSI) Approach to Inertial Focusing Dynamics under Dean Flow Patterns in Asymmetric Serpentines
Eric Pedrol, Jaume Massons, Francesc Díaz and Magdalena Aguiló
Fluids, 2018, 3, 62
DOI: 10.3390/fluids3030062

Optimal arrangements of inlet and outlet in topology liquid-cooled microchannel heat sink based on Multi-Objective optimization
Dingbiao Wang, Hongyang Song, Guanghui Wang, Yushen Yang, Shuai Wang and Sa Xiang
International Journal of Thermal Sciences, 2025, 209, 109552
DOI: 10.1016/j.ijthermalsci.2024.109552

Pressure drop and friction factor of a rectangular channel with staggered mini pin fins of different shapes
Hongxia Zhao, Zhigang Liu, Chengwu Zhang, Ning Guan and Honghua Zhao
Experimental Thermal and Fluid Science, 2016, 71, 57
DOI: 10.1016/j.expthermflusci.2015.10.010

Sheathless and high-throughput separation of multi-target particles combining inertia and deterministic lateral displacement (DLD) in a microchannel
Yuwen Lu, Jiaqian Ying, Shuoshuo Mu, Wei Tan and Guorui Zhu
Separation and Purification Technology, 2024, 345, 127369
DOI: 10.1016/j.seppur.2024.127369

Recent advances in microfluidic cell sorting techniques based on both physical and biochemical principles
Wenlai Tang, Di Jiang, Zongan Li, Liya Zhu, Jianping Shi, Jiquan Yang and Nan Xiang
Electrophoresis, 2019, 40, 930
DOI: 10.1002/elps.201800361

Inertial focusing of CTCs in a novel spiral microchannel
Afshin Shiriny and Morteza Bayareh
Chemical Engineering Science, 2021, 229, 116102
DOI: 10.1016/j.ces.2020.116102

Inertial particle separation in helical channels: A calibrated numerical analysis
Joshua Palumbo, Maryam Navi, Scott S. H. Tsai, Jan K. Spelt and Marcello Papini
AIP Advances, 2020, 10
DOI: 10.1063/5.0030930

Separation and sorting of cells in microsystems using physical principles
Gi-Hun Lee, Sung-Hwan Kim, Kihoon Ahn, Sang-Hoon Lee and Joong Yull Park
J. Micromech. Microeng., 2016, 26, 013003
DOI: 10.1088/0960-1317/26/1/013003

Elasto‐inertial particle focusing in sinusoidal microfluidic channels
Dalin Chen, Qiang Huang, Zhonghua Ni and Nan Xiang
Electrophoresis, 2024, 45, 2191
DOI: 10.1002/elps.202400070

Effects of obstacles on inertial focusing and separation in sinusoidal channels: An experimental and numerical study
Haotian Cha, Hoseyn A. Amiri, Sima Moshafi, Ali Karimi, Ali Nikkhah, Xiangxun Chen, Hang T. Ta, Nam-Trung Nguyen and Jun Zhang
Chemical Engineering Science, 2023, 276, 118826
DOI: 10.1016/j.ces.2023.118826

Label-Free Cancer Cell Separation from Human Whole Blood Using Inertial Microfluidics at Low Shear Stress
Myung Gwon Lee, Joong Ho Shin, Chae Yun Bae, Sungyoung Choi and Je-Kyun Park
Anal. Chem., 2013, 85, 6213
DOI: 10.1021/ac4006149

Microfluidic device for both active and passive cell separation techniques: A review
Muhammad Asraf Mansor, Muhammad Asyraf Jamrus, Chong Kar Lok, Mohd Ridzuan Ahmad, Michal Petrů and Seyed Saeid Rahimian Koloor
Sensors and Actuators Reports, 2025, 9, 100277
DOI: 10.1016/j.snr.2024.100277

Three-gradient constructions in a flow-rate insensitive microfluidic system for drug screening towards personalized treatment
Shaofei Shen, Xuan Zhang, Fangjuan Zhang, Defu Wang, Dandan Long and Yanbing Niu
Talanta, 2020, 208, 120477
DOI: 10.1016/j.talanta.2019.120477

Predictive Model for Cell Positioning during Periodic Lateral Migration in Spiral Microchannels
Kai Zheng, Zhaomiao Liu, Yan Pang, Xiang Wang, Siyu Zhao, Nan Zheng, Fanming Cai and Chenchen Zhang
Anal. Chem., 2024, 96, 18230
DOI: 10.1021/acs.analchem.4c04456

Advancements in differentiation between sperm cells and epithelial cells for efficient forensic DNA analysis in sexual assault cases
Hirak Ranjan Dash
Int J Legal Med, 2024, 138, 2209
DOI: 10.1007/s00414-024-03285-1

Size‐based cell sorting with a resistive pulse sensor and an electromagnetic pump in a microfluidic chip
Yongxin Song, Mengqi Li, Xinxiang Pan, Qi Wang and Dongqing Li
Electrophoresis, 2015, 36, 398
DOI: 10.1002/elps.201400292

Microslit on a chip: A simplified filter to capture circulating tumor cells enlarged with microbeads
Seung Joon Lee, Tae Seok Sim, Hyun Young Shin, Jungmin Lee, Min Young Kim, Joseph Sunoo, Jeong-Gun Lee, Kyungmoo Yea, Young Zoon Kim, Danny van Noort, Soo Kyung Park, Woon-Hae Kim, Kyun Woo Park, Minseok S. Kim and Jeffrey Chalmers
PLoS ONE, 2019, 14, e0223193
DOI: 10.1371/journal.pone.0223193

Label-Free and Rapid Microfluidic Design Rules for Circulating Tumor Cell Enrichment and Isolation: A Review and Simulation Analysis
Muhammad Asraf Mansor, Chun Yang, Kar Lok Chong, Muhammad Asyraf Jamrus, Kewei Liu, Miao Yu, Mohd Ridzuan Ahmad and Xiang Ren
ACS Omega, 2025, 10, 6306
DOI: 10.1021/acsomega.4c08606

Runway-shaped microchannel with flow rate insensitivity for high-throughput blood plasma extraction
Shuai Jin, Yu Liu and Sheng Hu
Chemical Engineering and Processing - Process Intensification, 2025, 215, 110384
DOI: 10.1016/j.cep.2025.110384

Microfluidic Screening of Circulating Tumor Biomarkers toward Liquid Biopsy
Nanjing Hao and John X.J. Zhang
Separation & Purification Reviews, 2018, 47, 19
DOI: 10.1080/15422119.2017.1320763

New insights into the physics of inertial microfluidics in curved microchannels. I. Relaxing the fixed inflection point assumption
Mehdi Rafeie, Shahin Hosseinzadeh, Robert A. Taylor and Majid Ebrahimi Warkiani
Biomicrofluidics, 2019, 13
DOI: 10.1063/1.5109004

A microfluidic concentrator for cyanobacteria harvesting
Lei Wang and David S. Dandy
Algal Research, 2017, 26, 481
DOI: 10.1016/j.algal.2017.03.018

Microfluidic Air Sampler for Highly Efficient Bacterial Aerosol Collection and Identification
Xiaojun Bian, Ying Lan, Bing Wang, Yu Shrike Zhang, Baohong Liu, Pengyuan Yang, Weijia Zhang and Liang Qiao
Anal. Chem., 2016, 88, 11504
DOI: 10.1021/acs.analchem.6b02708

Inertial migration of cylindrical micelles formed by comb-like copolymer in Poiseuille flow
Mingtao Lin, Qingfeng Shi, Xiang Yang and Mingming Ding
Physics of Fluids, 2024, 36
DOI: 10.1063/5.0225531

Microfluidics for producing poly (lactic-co-glycolic acid)-based pharmaceutical nanoparticles
Xuanyu Li and Xingyu Jiang
Advanced Drug Delivery Reviews, 2018, 128, 101
DOI: 10.1016/j.addr.2017.12.015

Recent advances in microfluidic technology for manipulation and analysis of biological cells (2007–2017)
Md Kowsar Alam, Emmanuel Koomson, Heng Zou, Changqing Yi, Cheuk-Wing Li, Tao Xu and Mengsu Yang
Analytica Chimica Acta, 2018, 1044, 29
DOI: 10.1016/j.aca.2018.06.054

Size-Based Separation of Particles and Cells Utilizing Viscoelastic Effects in Straight Microchannels
Chao Liu, Chundong Xue, Xiaodong Chen, Lei Shan, Yu Tian and Guoqing Hu
Anal. Chem., 2015, 87, 6041
DOI: 10.1021/acs.analchem.5b00516

New insights into the physics of inertial microfluidics in curved microchannels. II. Adding an additive rule to understand complex cross-sections
Mehdi Rafeie, Shahin Hosseinzadeh, Jingrui Huang, Asma Mihandoust, Majid Ebrahimi Warkiani and Robert A. Taylor
Biomicrofluidics, 2019, 13
DOI: 10.1063/1.5109012

Inertial microfluidics: Recent advances
Di Huang, Jiaxiang Man, Di Jiang, Jiyun Zhao and Nan Xiang
Electrophoresis, 2020, 41, 2166
DOI: 10.1002/elps.202000134

Global stability of trajectories of inertial particles within domains of instability
Senbagaraman Sudarsanam and Phanindra Tallapragada
Communications in Nonlinear Science and Numerical Simulation, 2017, 42, 313
DOI: 10.1016/j.cnsns.2016.05.025

Current techniques and future advance of microfluidic devices for circulating tumor cells
Shi-Bo Cheng, Miao-Miao Chen, Yi-Ke Wang, Zi-Han Sun, Min Xie and Wei-Hua Huang
TrAC Trends in Analytical Chemistry, 2019, 117, 116
DOI: 10.1016/j.trac.2019.06.018

Label-free microfluidic sorting of microparticles
Jian Zhou, Prithviraj Mukherjee, Hua Gao, Qiyue Luan and Ian Papautsky
APL Bioengineering, 2019, 3
DOI: 10.1063/1.5120501

A short review of spiral microfluidic devices with distinct cross-sectional geometries
S. Ramya, S. Praveen Kumar, G. Dinesh Ram and D. Lingaraja
Microfluid Nanofluid, 2022, 26
DOI: 10.1007/s10404-022-02593-5

Label-Free, High-Throughput Assay of Human Dendritic Cells from Whole-Blood Samples with Microfluidic Inertial Separation Suitable for Resource-Limited Manufacturing
Mohamed Yousuff Caffiyar, Kue Peng Lim, Ismail Hussain Kamal Basha, Nor Hisham Hamid, Sok Ching Cheong and Eric Tatt Wei Ho
Micromachines, 2020, 11, 514
DOI: 10.3390/mi11050514

Serial Separation of Microalgae in a Microfluidic Chip Under Inertial and Dielectrophoretic Forces
Yanjuan Wang, Junsheng Wang, Jiale Cheng, Yichi Zhang, Gege Ding, Xin Wang, Mengmeng Chen, Yuejun Kang and Xinxiang Pan
IEEE Sensors J., 2020, 20, 14607
DOI: 10.1109/JSEN.2020.3011403

Selective Segregation of Thermo‐Responsive Microgels via Microfluidic Technology
Anjali Sharma, Fabian Rohne, Daniela Vasquez‐Muñoz, Se‐Hyeong Jung, Nino Lomadze, Andrij Pich, Svetlana Santer and Marek Bekir
Small Methods, 2024, 8
DOI: 10.1002/smtd.202400226

Biological particle separation techniques based on microfluidics
Saijie Wang, Quanchen Xu, Yanwei Cai, Qian Wang, Ying Liu and Dou Wang
Interdisciplinary Medicine, 2024, 2
DOI: 10.1002/INMD.20240003

Morphological Differences between Circulating Tumor Cells from Prostate Cancer Patients and Cultured Prostate Cancer Cells
Sunyoung Park, Richard R. Ang, Simon P. Duffy, Jenny Bazov, Kim N. Chi, Peter C. Black, Hongshen Ma and David T. Eddington
PLoS ONE, 2014, 9, e85264
DOI: 10.1371/journal.pone.0085264

Flexible Electronic Catheter Based on Nanofibers for the In Vivo Elimination of Circulating Tumor Cells
Dou Wang, Ruihua Dong, Xuedong Wang and Xingyu Jiang
ACS Nano, 2022, 16, 5274
DOI: 10.1021/acsnano.1c09807

An Integrated Microfluidic Chip System for Single-Cell Secretion Profiling of Rare Circulating Tumor Cells
Yuliang Deng, Yu Zhang, Shuai Sun, Zhihua Wang, Minjiao Wang, Beiqin Yu, Daniel M. Czajkowsky, Bingya Liu, Yan Li, Wei Wei and Qihui Shi
Sci Rep, 2014, 4
DOI: 10.1038/srep07499

A microfluidic device for enhanced capture and high activity release of heterogeneous CTCs from whole blood
Qiaoyu Li, Yanlin Wang, Wenjing Gao, Guoqing Qian, Xueqin Chen, Yushan Liu and Shaoning Yu
Talanta, 2024, 266, 125007
DOI: 10.1016/j.talanta.2023.125007

Design and Numerical Analysis of a Single Inlet-Based Spiral Microfluidic Chip for Separation of Circulating Tumor Cells and Blood Plasma Using the Inertial Focusing Approach
Writtick Pakhira, R. Kumar, Khalid Mohd. Ibrahimi and Rituraj Bhattacharjee
Chromatographia, 2025, 88, 453
DOI: 10.1007/s10337-025-04411-w

A needle tip CCEA microfluidic device based on enhanced Dean flow for cell washing
Xin Shi, Wei Tan, Yuwen Lu, Wenfeng Cao and Guorui Zhu
Microsyst Nanoeng, 2021, 7
DOI: 10.1038/s41378-021-00311-9

Electricity-free hand-held inertial microfluidic sorter for size-based cell sorting
Nan Xiang and Zhonghua Ni
Talanta, 2021, 235, 122807
DOI: 10.1016/j.talanta.2021.122807

Detection and isolation of circulating tumor cells: Principles and methods
Hadi Esmaeilsabzali, Timothy V. Beischlag, Michael E. Cox, Ash M. Parameswaran and Edward J. Park
Biotechnology Advances, 2013, 31, 1063
DOI: 10.1016/j.biotechadv.2013.08.016

A Review of Secondary Flow in Inertial Microfluidics
Qianbin Zhao, Dan Yuan, Jun Zhang and Weihua Li
Micromachines, 2020, 11, 461
DOI: 10.3390/mi11050461

Particle Focusing and Separation in the Low Aspect Ratio Serpentine‐Hook Shape Microarray
Keihan Amin, Shahaboldin Bahrami Balani and Naser Naserifar
Separation Science Plus, 2024, 7
DOI: 10.1002/sscp.202400198

Detection of circulating tumor cells and single cell extraction technology: principle, effect and application prospect
Rui Li, Zhiyi Gong, Yichao Liu, Xingzhong Zhao and Shishang Guo
Nano Futures, 2021, 5, 032002
DOI: 10.1088/2399-1984/ac1325

Active control of particle position by boundary slip in inertial microfluidics
Chengliang Xuan, Weiyin Liang, Bing He and Binghai Wen
Phys. Rev. Fluids, 2022, 7
DOI: 10.1103/PhysRevFluids.7.064201

Inertial particle separation by differential equilibrium positions in a symmetrical serpentine micro-channel
Jun Zhang, Sheng Yan, Ronald Sluyter, Weihua Li, Gursel Alici and Nam-Trung Nguyen
Sci Rep, 2014, 4
DOI: 10.1038/srep04527

A Multilayer Polymer-Film Inertial Microfluidic Device for High-Throughput Cell Concentration
Nan Xiang, Rui Zhang, Yu Han and Zhonghua Ni
Anal. Chem., 2019, 91, 5461
DOI: 10.1021/acs.analchem.9b01116

A Microfluidic Prototype System towards Microalgae Cell Separation, Treatment and Viability Characterization
Yanjuan Wang, Junsheng Wang, Chen Zhou, Gege Ding, Mengmeng Chen, Jiang Zou, Ge Wang, Yuejun Kang and Xinxiang Pan
Sensors, 2019, 19, 4940
DOI: 10.3390/s19224940

Separation of particles in spiral micro-channel using Dean’s flow fractionation
Puja Mitra, Samik Dutta, Nagahanumaiah and Abhiram Hens
J Braz. Soc. Mech. Sci. Eng., 2020, 42
DOI: 10.1007/s40430-020-02482-4

Multiplexed serpentine microchannels for high-throughput sorting of disseminated tumor cells from malignant pleural effusion
Hui Ren, Zhixian Zhu, Nan Xiang, Hao Wang, Tingting Zheng, Hongjie An, Nam-Trung Nguyen and Jun Zhang
Sensors and Actuators B: Chemical, 2021, 337, 129758
DOI: 10.1016/j.snb.2021.129758

Highly efficient capture of circulating tumor cells with low background signals by using pyramidal microcavity array
Jiaxiang Yin, Lei Mou, Mingzhu Yang, Wenwu Zou, Chang Du, Wei Zhang and Xingyu Jiang
Analytica Chimica Acta, 2019, 1060, 133
DOI: 10.1016/j.aca.2019.01.054

Comparison of logarithmic, elliptic, and conical helical spiral for isolation of circulating tumor cells based on inertial method
Amir Shamloo, Yasaman Mozhdehbakhsh Mofrad, Morteza Safari and Tahoora Naseri
Physics of Fluids, 2022, 34
DOI: 10.1063/5.0100079

The incorporation of microfluidics into circulating tumor cell isolation for clinical applications
Molly Kozminsky, Yang Wang and Sunitha Nagrath
Current Opinion in Chemical Engineering, 2016, 11, 59
DOI: 10.1016/j.coche.2016.01.005

High-Throughput Particle Manipulation Based on Hydrodynamic Effects in Microchannels
Chao Liu and Guoqing Hu
Micromachines, 2017, 8, 73
DOI: 10.3390/mi8030073

Size-based hydrodynamic rare tumor cell separation in curved microfluidic channels
Jiashu Sun, Chao Liu, Mengmeng Li, Jidong Wang, Yunlei Xianyu, Guoqing Hu and Xingyu Jiang
Biomicrofluidics, 2013, 7
DOI: 10.1063/1.4774311

Consecutive Sorting and Phenotypic Counting of CTCs by an Optofluidic Flow Cytometer
Qingling Li, Shuang Cui, Yuehan Xu, Yiguo Wang, Feng Jin, Haibin Si, Lu Li and Bo Tang
Anal. Chem., 2019, 91, 14133
DOI: 10.1021/acs.analchem.9b04035

Label-free isolation of circulating tumor cells using negative lateral dielectrophoresis-assisted inertial microfluidics
Aliasghar Mohammadi, Morteza Safari and Mehdi Rahmanian
Microfluid Nanofluid, 2023, 27
DOI: 10.1007/s10404-023-02662-3

Experiment study on focusing pattern prediction of particles in asymmetric contraction–expansion array channel
Xin Shi, Qing He, Wei Tan, Yuwen Lu and Guorui Zhu
Electrophoresis, 2024, 45, 2169
DOI: 10.1002/elps.202400042

Review: Microfluidics technologies for blood-based cancer liquid biopsies
Yuxi Sun, Thomas A. Haglund, Aaron J. Rogers, Asem F. Ghanim and Palaniappan Sethu
Analytica Chimica Acta, 2018, 1012, 10
DOI: 10.1016/j.aca.2017.12.050

Microfluidics‐Based Biomaterials and Biodevices
Ruihua Dong, Yong Liu, Lei Mou, Jinqi Deng and Xingyu Jiang
Advanced Materials, 2019, 31
DOI: 10.1002/adma.201805033

Folic Acid-Functionalized Hybrid Photonic Barcodes for Capture and Release of Circulating Tumor Cells
Chengxin Luan, Huan Wang, Qi Han, Xiaoyan Ma, Dagan Zhang, Yueshuang Xu, Baoan Chen, Minli Li and Yuanjin Zhao
ACS Appl. Mater. Interfaces, 2018, 10, 21206
DOI: 10.1021/acsami.8b06882

The mechanisms and properties of inertial microfluidics: from fundamental models to biomedical applications
Shlok Mishra, Joydeb Mukherjee, Deepa Chaturvedi, Ratnesh Jain and Prajakta Dandekar
Microfluid Nanofluid, 2023, 27
DOI: 10.1007/s10404-023-02692-x

Study of Local Inertial Focusing Conditions for Spherical Particles in Asymmetric Serpentines
Eric Pedrol, Jaume Massons, Francesc Díaz and Magdalena Aguiló
Fluids, 2019, 5, 1
DOI: 10.3390/fluids5010001

Enhanced Separation Efficiency and Purity of Circulating Tumor Cells Based on the Combined Effects of Double Sheath Fluids and Inertial Focusing
Bo-Wen Li, Kun Wei, Qi-Qi Liu, Xian-Ge Sun, Ning Su, Wen-Man Li, Mei-Yun Shang, Jin-Mi Li, Dan Liao, Jin Li, Wei-Ping Lu, Shao-Li Deng and Qing Huang
Front. Bioeng. Biotechnol., 2021, 9
DOI: 10.3389/fbioe.2021.750444

Circulating Tumor Cell Enrichment Based on Physical Properties
Ramdane A. Harouaka, Merisa Nisic and Si-Yang Zheng
SLAS Technology, 2013, 18, 455
DOI: 10.1177/2211068213494391

Analysis of circulating tumour cells separation in a curved microchannel under a high gravitational field
Ahmed A. Ayash
Chemical Engineering Science, 2023, 265, 118235
DOI: 10.1016/j.ces.2022.118235

Double-Mode Microparticle Manipulation by Tunable Secondary Flow in Microchannel With Arc-Shaped Groove Arrays
Qianbin Zhao, Sheng Yan, Dan Yuan, Jun Zhang, Haiping Du, Gursel Alici and Weihua Li
IEEE Trans. Biomed. Circuits Syst., 2017, 11, 1406
DOI: 10.1109/TBCAS.2017.2722012

Cascaded spiral microfluidic device for deterministic and high purity continuous separation of circulating tumor cells
Tae Hyun Kim, Hyeun Joong Yoon, Philip Stella and Sunitha Nagrath
Biomicrofluidics, 2014, 8
DOI: 10.1063/1.4903501

Label-Free Isolation and mRNA Detection of Circulating Tumor Cells from Patients with Metastatic Lung Cancer for Disease Diagnosis and Monitoring Therapeutic Efficacy
Jidong Wang, Wenjing Lu, Chuanhao Tang, Yi Liu, Jiashu Sun, Xuan Mu, Lin Zhang, Bo Dai, Xiaoyan Li, Hailong Zhuo and Xingyu Jiang
Anal. Chem., 2015, 87, 11893
DOI: 10.1021/acs.analchem.5b03484

New Generation of Ensemble-Decision Aliquot Ranking Based on Simplified Microfluidic Components for Large-Capacity Trapping of Circulating Tumor Cells
Mengxia Zhao, Wyatt C. Nelson, Bingchuan Wei, Perry G. Schiro, Bejan M. Hakimi, Eleanor S. Johnson, Robbyn K. Anand, Grace S. Gyurkey, Lisa M. White, Samuel H. Whiting, Andrew L. Coveler and Daniel T. Chiu
Anal. Chem., 2013, 85, 9671
DOI: 10.1021/ac401985r

Microfluidics-based approaches for separation and analysis of circulating tumor cells
Jiaxiang Yin, Jinqi Deng, Chang Du, Wei Zhang and Xingyu Jiang
TrAC Trends in Analytical Chemistry, 2019, 117, 84
DOI: 10.1016/j.trac.2019.07.018

Continuous particle separation of microfluidic chip with integrated inertial separation and dielectrophoresis separation
Xiaohong Li, Junping Duan, Jiayun Wang, Zeng Qu, Miaomiao Ji and BinZhen Zhang
AIP Advances, 2022, 12
DOI: 10.1063/5.0075823

Inertial migration of deformable droplets in a microchannel
Xiaodong Chen, Chundong Xue, Li Zhang, Guoqing Hu, Xingyu Jiang and Jiashu Sun
Physics of Fluids, 2014, 26
DOI: 10.1063/1.4901884

Spiral-shaped inertial stem cell device for high-throughput enrichment of iPSC-derived neural stem cells
Hongjun Song, Jenna M. Rosano, Yi Wang, Charles J. Garson, Balabhaskar Prabhakarpandian, Kapil Pant, George J. Klarmann, Luis M. Alvarez and Eva Lai
Microfluid Nanofluid, 2017, 21
DOI: 10.1007/s10404-017-1896-5

Geometric structure design of passive label-free microfluidic systems for biological micro-object separation
Hao Tang, Jiaqi Niu, Han Jin, Shujing Lin and Daxiang Cui
Microsyst Nanoeng, 2022, 8
DOI: 10.1038/s41378-022-00386-y

High-Throughput White Blood Cell (Leukocyte) Enrichment from Whole Blood Using Hydrodynamic and Inertial Forces
Batzorig Lombodorj, Horas Cendana Tseng, Hwan-You Chang, Yen-Wen Lu, Namnan Tumurpurev, Chun-Wei Lee, Batdemberel Ganbat, Ren-Guei Wu and Fan-Gang Tseng
Micromachines, 2020, 11, 275
DOI: 10.3390/mi11030275

Dean migration of unfocused micron sized particles in low aspect ratio spiral microchannels
Suhanya Duraiswamy and Lin Yue Lanry Yung
Biomed Microdevices, 2021, 23
DOI: 10.1007/s10544-021-00575-y

Real-time Functional Analysis of Inertial Microfluidic Devices via Spectral Domain Optical Coherence Tomography
Biqin Dong, Siyu Chen, Fan Zhou, Christina H. Y. Chan, Ji Yi, Hao F. Zhang and Cheng Sun
Sci Rep, 2016, 6
DOI: 10.1038/srep33250

Nanotechnology Applications in Diagnosis and Treatment of Metastasis
Anirban Sen Gupta
Nanomedicine, 2014, 9, 1517
DOI: 10.2217/nnm.14.94

Recent Progress of Microfluidics in Translational Applications
Zongbin Liu, Xin Han and Lidong Qin
Adv Healthcare Materials, 2016, 5, 871
DOI: 10.1002/adhm.201600009

The effect of varying radius of curvature on mixing in elliptical spiral microchannels
Rana Altay, Abuzer Alp Yetisgin, Kaan Erdem and Ali Koşar
Chemical Engineering and Processing - Process Intensification, 2021, 164, 108401
DOI: 10.1016/j.cep.2021.108401

High-throughput particle separation and concentration using spiral inertial filtration
Jeffrey M. Burke, Rebecca E. Zubajlo, Elisabeth Smela and Ian M. White
Biomicrofluidics, 2014, 8
DOI: 10.1063/1.4870399

Differential Sorting of Microparticles Using Spiral Microchannels with Elliptic Configurations
Kaan Erdem, Vahid Ebrahimpour Ahmadi, Ali Kosar and Lütfullah Kuddusi
Micromachines, 2020, 11, 412
DOI: 10.3390/mi11040412

Microfluidic Synthesis of Hybrid Nanoparticles with Controlled Lipid Layers: Understanding Flexibility-Regulated Cell–Nanoparticle Interaction
Lu Zhang, Qiang Feng, Jiuling Wang, Shuai Zhang, Baoquan Ding, Yujie Wei, Mingdong Dong, Ji-Young Ryu, Tae-Young Yoon, Xinghua Shi, Jiashu Sun and Xingyu Jiang
ACS Nano, 2015, 9, 9912
DOI: 10.1021/acsnano.5b05792

Experimental study on inertial focusing pattern in asymmetric contraction–expansion array microchannel
Guorui Zhu, Ziqian Zhang, Xin Shi and Wei Tan
Microfluid Nanofluid, 2022, 26
DOI: 10.1007/s10404-021-02510-2

A Hybrid Spiral Microfluidic Platform Coupled with Surface Acoustic Waves for Circulating Tumor Cell Sorting and Separation: A Numerical Study
Rana Altay, Murat Kaya Yapici and Ali Koşar
Biosensors, 2022, 12, 171
DOI: 10.3390/bios12030171

Insights on CTC Biology and Clinical Impact Emerging from Advances in Capture Technology
Patrick Bailey and Stuart Martin
Cells, 2019, 8, 553
DOI: 10.3390/cells8060553

Hybrid microfluidics combined with active and passive approaches for continuous cell separation
Sheng Yan, Jun Zhang, Dan Yuan and Weihua Li
Electrophoresis, 2017, 38, 238
DOI: 10.1002/elps.201600386

Separation of sperm and epithelial cells based on the hydrodynamic effect for forensic analysis
Weiran Liu, Weixing Chen, Ran Liu, Yuan Ou, Haoran Liu, Lan Xie, Ying Lu, Caixia Li, Bin Li and Jing Cheng
Biomicrofluidics, 2015, 9
DOI: 10.1063/1.4928453

Single-actuator Bandpass Microparticle Filtration via Traveling Surface Acoustic Waves
Zhichao Ma, David J. Collins and Ye Ai
Colloid and Interface Science Communications, 2017, 16, 6
DOI: 10.1016/j.colcom.2016.12.001

Cell–surface interactions on gold‐coated polydimethylsiloxane nanocomposite structures: Localized laser heating on cell viability
Yiporo Danyuo, John David Obayemi, Ali Azeko Salifu, Oluwaseun Kehinde Oyewole, ‪Salifu Tahiru Azeko, Chukwuemeka Joseph Ani, Stella Dozie‐Nwachukwu, John Yirijor, Miriam Abade‐Abugre, Olushola Segun Odusanya, Fred McBagonluri and Winston Oluwole Soboyejo
J Biomedical Materials Res, 2021, 109, 2611
DOI: 10.1002/jbm.a.37254

Nanomaterials for Ultrasensitive Protein Detection
Yi Zhang, Yongming Guo, Yunlei Xianyu, Wenwen Chen, Yuyun Zhao and Xingyu Jiang
Advanced Materials, 2013, 25, 3802
DOI: 10.1002/adma.201301334

Separation of U87 glioblastoma cell-derived small and medium extracellular vesicles using elasto-inertial flow focusing (a spiral channel)
Farhad Shiri, Haidong Feng, Kevin E. Petersen, Himanshu Sant, Gina T. Bardi, Luke A. Schroeder, Michael L. Merchant, Bruce K. Gale and Joshua L. Hood
Sci Rep, 2022, 12
DOI: 10.1038/s41598-022-10129-8

Clinical isolation of breast cancer Circulating Tumor Cells with an inertial microfluidic chip with a trapezoidal cross-section
Zahra Sadeghi, Mohsen Nasr Esfahany, Hossein Salehi and Azar Baradaran
Biochemical Engineering Journal, 2025, 221, 109788
DOI: 10.1016/j.bej.2025.109788

High-Throughput Selective Capture of Single Circulating Tumor Cells by Dielectrophoresis at a Wireless Electrode Array
Min Li and Robbyn K. Anand
J. Am. Chem. Soc., 2017, 139, 8950
DOI: 10.1021/jacs.7b03288

Numerical Simulation of Inertial Based PDMS Microchannel for Blood Cell Sorting
S. Ramya, S. Praveen Kumar, G. Dinesh Ram and D. Lingaraja
Trans. Electr. Electron. Mater., 2023, 24, 412
DOI: 10.1007/s42341-023-00459-3

Isolation and retrieval of circulating tumor cells on a microchip with double parallel layers of herringbone structure
Peng Xue, Lei Zhang, Jinhong Guo, Zhigang Xu and Yuejun Kang
Microfluid Nanofluid, 2016, 20
DOI: 10.1007/s10404-016-1834-y

Inertial force-assisted microfluidic chip-ICPMS for the study ofnano-Al<sub>2</sub>O<sub>3</sub> uptake by single cells
Xing Wei, Yang Song, Yu-Jia Wei, Ming-Li Chen and Jian-Hua Wang
Sci. Sin.-Chim, 2022, 52, 1730
DOI: 10.1360/SSC-2022-0132

Design and validation of a tunable inertial microfluidic system for the efficient enrichment of circulating tumor cells in blood
Alejandro Rodríguez‐Pena, Estibaliz Armendariz, Alvaro Oyarbide, Xabier Morales, Sergio Ortiz‐Espinosa, Borja Ruiz‐Fernández de Córdoba, Denis Cochonneau, Iñaki Cornago, Dominique Heymann, Josepmaría Argemi, Delia D'Avola, Bruno Sangro, Fernando Lecanda, Ruben Pio, Iván Cortés‐Domínguez and Carlos Ortiz‐de‐Solórzano
Bioengineering & Transla Med, 2022, 7
DOI: 10.1002/btm2.10331

Continuous Flow Microfluidic Bioparticle Concentrator
Joseph M. Martel, Kyle C. Smith, Mcolisi Dlamini, Kendall Pletcher, Jennifer Yang, Murat Karabacak, Daniel A. Haber, Ravi Kapur and Mehmet Toner
Sci Rep, 2015, 5
DOI: 10.1038/srep11300

Inertia-induced focusing dynamics of microparticles throughout a curved microfluidic channel
Nan Xiang, Ke Chen, Qing Dai, Di Jiang, Dongke Sun and Zhonghua Ni
Microfluid Nanofluid, 2015, 18, 29
DOI: 10.1007/s10404-014-1395-x

Low‐cost multi‐core inertial microfluidic centrifuge for high‐throughput cell concentration
Nan Xiang, Qiao Li, Zhiguo Shi, Chenguang Zhou, Fengtao Jiang, Yu Han and Zhonghua Ni
Electrophoresis, 2020, 41, 875
DOI: 10.1002/elps.201900385

High-throughput blood cell focusing and plasma isolation using spiral inertial microfluidic devices
Nan Xiang and Zhonghua Ni
Biomed Microdevices, 2015, 17
DOI: 10.1007/s10544-015-0018-y

Inertial-based Fluidic Platform for Rapid Isolation of Blood-borne Pathogens
Erin C Batcho, Sinead Miller, Timothy L Cover, Mark S McClain, Christina Marasco, Charleson S Bell and Todd D Giorgio
Military Medicine, 2021, 186, 129
DOI: 10.1093/milmed/usaa442

Microfluidic device with integrated microfilter of conical-shaped holes for high efficiency and high purity capture of circulating tumor cells
Yadong Tang, Jian Shi, Sisi Li, Li Wang, Yvon E. Cayre and Yong Chen
Sci Rep, 2014, 4
DOI: 10.1038/srep06052

Tunable Rigidity of (Polymeric Core)–(Lipid Shell) Nanoparticles for Regulated Cellular Uptake
Jiashu Sun, Lu Zhang, Jiuling Wang, Qiang Feng, Dingbin Liu, Qifang Yin, Dongyan Xu, Yujie Wei, Baoquan Ding, Xinghua Shi and Xingyu Jiang
Advanced Materials, 2015, 27, 1402
DOI: 10.1002/adma.201404788

High-efficiency rare cell identification on a high-density self-assembled cell arrangement chip
Tsung-Ju Chen, Jen-Kuei Wu, Yu-Cheng Chang, Chien-Yu Fu, Tsung-Pao Wang, Chun-Yen Lin, Hwan-You Chang, Ching-Chang Chieng, Chung-Yuh Tzeng and Fan-Gang Tseng
Biomicrofluidics, 2014, 8
DOI: 10.1063/1.4874716

Exploring contraction–expansion inertial microfluidic‐based particle separation devices integrated with curved channels
Amir Shamloo, Seyedamirhosein Abdorahimzadeh and Rohollah Nasiri
AIChE Journal, 2019, 65
DOI: 10.1002/aic.16741

Microfluidic processing of stem cells for autologous cell replacement
Nicholas E. Stone, Andrew P. Voigt, Robert F. Mullins, Todd Sulchek and Budd A. Tucker
STEM CELLS Transl Med, 2021, 10, 1384
DOI: 10.1002/sctm.21-0080

Recent advances in microfluidic methods in cancer liquid biopsy
Florina S. Iliescu, Daniel P. Poenar, Fang Yu, Ming Ni, Kiat Hwa Chan, Irina Cima, Hayden K. Taylor, Igor Cima and Ciprian Iliescu
Biomicrofluidics, 2019, 13
DOI: 10.1063/1.5087690

Separation of sperm cells from samples containing high concentrations of white blood cells using a spiral channel
Jiyoung Son, Raheel Samuel, Bruce K. Gale, Douglas T. Carrell and James M. Hotaling
Biomicrofluidics, 2017, 11
DOI: 10.1063/1.4994548

Scale invariant hydrodynamic focusing and sorting of inertial particles by size in spiral micro channels
Phanindra Tallapragada, Nilesh Hasabnis, Kalyan Katuri, Senbagaraman Sudarsanam, Ketaki Joshi and Melur Ramasubramanian
J. Micromech. Microeng., 2015, 25, 084013
DOI: 10.1088/0960-1317/25/8/084013

Numerical investigation of centrifugal passive cell separation in three types of serpentine microchannels and comparison with fixed platform
Rasool Dezhkam, Ali Shafiei Souderjani, Amir Shamloo, Mohammadmahdi Eskandarisani and Ali Mashhadian
Journal of Industrial and Engineering Chemistry, 2023, 124, 240
DOI: 10.1016/j.jiec.2023.04.013

Dean flow-coupled inertial focusing in curved channels
Harisha Ramachandraiah, Sahar Ardabili, Asim M. Faridi, Jesper Gantelius, Jacob M. Kowalewski, Gustaf Mårtensson and Aman Russom
Biomicrofluidics, 2014, 8
DOI: 10.1063/1.4884306

3D printed microfluidic devices for circulating tumor cells (CTCs) isolation
Juhong Chen, Chun-Yen Liu, Xinchang Wang, Eric Sweet, Nathaniel Liu, Xiaohua Gong and Liwei Lin
Biosensors and Bioelectronics, 2020, 150, 111900
DOI: 10.1016/j.bios.2019.111900

Assessment of Lagrangian Modeling of Particle Motion in a Spiral Microchannel for Inertial Microfluidics
Reza Rasooli and Barbaros Çetin
Micromachines, 2018, 9, 433
DOI: 10.3390/mi9090433

An integrated experimental–computational study of mesenchymal stem cell dynamics in confined microfluidic systems
Xiaojing Qi, Xinchi Jiang, Juanjuan Zheng, Rouxuan Wang, Yuankai Sun, Jianqing Gao and Xuejin Li
Biomicrofluidics, 2025, 19
DOI: 10.1063/5.0276147

A Microbore Tubing Based Spiral for Multistep Cell Fractionation
Laura Pasitka, Danny van Noort, Wanyoung Lim, Sungsu Park and Carl-Fredrik Mandenius
Anal. Chem., 2018, 90, 12909
DOI: 10.1021/acs.analchem.8b03532

Continuous microfluidic 3D focusing enabling microflow cytometry for single-cell analysis
Sheng Yan and Dan Yuan
Talanta, 2021, 221, 121401
DOI: 10.1016/j.talanta.2020.121401

Spiral microchannel with rectangular and trapezoidal cross-sections for size based particle separation
Guofeng Guan, Lidan Wu, Ali Asgar Bhagat, Zirui Li, Peter C. Y. Chen, Shuzhe Chao, Chong Jin Ong and Jongyoon Han
Sci Rep, 2013, 3
DOI: 10.1038/srep01475

An efficient spiral microchannel for continuous small particle separations
P.Y. Yeh, Z. Dai, X. Yang, M. Bergeron, Z. Zhang, M. Lin and X. Cao
Sensors and Actuators B: Chemical, 2017, 252, 606
DOI: 10.1016/j.snb.2017.06.037

Inertial Focusing in Microfluidics
Joseph M. Martel and Mehmet Toner
Annu. Rev. Biomed. Eng., 2014, 16, 371
DOI: 10.1146/annurev-bioeng-121813-120704

Colorimetric Logic Gates through Molecular Recognition and Plasmonic Nanoparticles
Yunlei Xianyu, Zhuo Wang, Jiashu Sun, Xuefei Wang and Xingyu Jiang
Small, 2014, 10, 4833
DOI: 10.1002/smll.201400479

River meander-inspired cross-section in 3D-printed helical microchannels for inertial focusing and enrichment
Zezhou Chen, Lei Zhao, Lujie Wei, Ziyu Huang, Pengju Yin, Xiaowen Huang, Hongyan Shi, Bo Hu and Jie Tian
Sensors and Actuators B: Chemical, 2019, 301, 127125
DOI: 10.1016/j.snb.2019.127125

High‐Throughput Inertial Focusing of Micrometer‐ and Sub‐Micrometer‐Sized Particles Separation
Lei Wang and David S. Dandy
Advanced Science, 2017, 4
DOI: 10.1002/advs.201700153

Design of a Microfluidic Chip for Enrichment of Circulating Tumor Cells
Xi Xin Ling, Da Hai Ren and Zheng You
KEM, 2015, 645-646, 1320
DOI: 10.4028/www.scientific.net/KEM.645-646.1320

High-throughput inertial particle focusing in a curved microchannel: Insights into the flow-rate regulation mechanism and process model
Nan Xiang, Hong Yi, Ke Chen, Dongke Sun, Di Jiang, Qing Dai and Zhonghua Ni
Biomicrofluidics, 2013, 7
DOI: 10.1063/1.4818445

Rapid and Label-Free Separation of Burkitt's Lymphoma Cells from Red Blood Cells by Optically-Induced Electrokinetics
Wenfeng Liang, Yuliang Zhao, Lianqing Liu, Yuechao Wang, Zaili Dong, Wen Jung Li, Gwo-Bin Lee, Xiubin Xiao, Weijing Zhang and Masaya Yamamoto
PLoS ONE, 2014, 9, e90827
DOI: 10.1371/journal.pone.0090827

Lateral migration of dual droplet trains in a double spiral microchannel
ChunDong Xue, XiaoDong Chen, Chao Liu and GuoQing Hu
Sci. China Phys. Mech. Astron., 2016, 59
DOI: 10.1007/s11433-016-0115-1

Effects of Shear and Extensional Stresses on Cells: Investigation in a Spiral Microchannel and Contraction–Expansion Arrays
Thammawit Suwannaphan, Ampol Kamnerdsook, Suramate Chalermwisutkul, Boonchai Techaumnat, Nattapol Damrongplasit, Bhawat Traipattanakul, Surasak Kasetsirikul and Alongkorn Pimpin
ACS Biomater. Sci. Eng., 2025, 11, 3249
DOI: 10.1021/acsbiomaterials.5c00555

A single‐view field filter device for rare tumor cell filtration and enumeration
Yunlin Quan, Ke Chen, Nan Xiang and Zhonghua Ni
Electrophoresis, 2020, 41, 2000
DOI: 10.1002/elps.202000176

High-Throughput Microfluidic Labyrinth for the Label-free Isolation of Circulating Tumor Cells
Eric Lin, Lianette Rivera-Báez, Shamileh Fouladdel, Hyeun Joong Yoon, Stephanie Guthrie, Jacob Wieger, Yadwinder Deol, Evan Keller, Vaibhav Sahai, Diane M. Simeone, Monika L. Burness, Ebrahim Azizi, Max S. Wicha and Sunitha Nagrath
Cell Systems, 2017, 5, 295
DOI: 10.1016/j.cels.2017.08.012

Splicing Nanoparticles-Based “Click” SERS Could Aid Multiplex Liquid Biopsy and Accurate Cellular Imaging
Yi Zeng, Jia-Qiang Ren, Ai-Guo Shen and Ji-Ming Hu
J. Am. Chem. Soc., 2018, 140, 10649
DOI: 10.1021/jacs.8b04892

Distinct separation of multiple CTCs using inertial focusing phenomena utilizing single-looped spiral microfluidic lab-on-chip
Writtick Pakhira, R. Kumar and Khalid Mohd. Ibrahimi
Chemical Engineering Science, 2023, 275, 118724
DOI: 10.1016/j.ces.2023.118724

A multilayer lateral-flow microfluidic device for particle separation
Youwei Jiang, Zhenming Yu, Xinglong Huang, Rifei Chen, Weiyuan Chen, Yifan Zeng, Chengqi Xu, Haodi Min, Nan Zheng and Xing Cheng
Microfluid Nanofluid, 2018, 22
DOI: 10.1007/s10404-018-2053-5

An integrated inertial microfluidic vortex sorter for tunable sorting and purification of cells
Xiao Wang, Xiaodi Yang and Ian Papautsky
Technology, 2016, 04, 88
DOI: 10.1142/S2339547816400112

Lab-on-a-Chip Technologies for the Single Cell Level: Separation, Analysis, and Diagnostics
Axel Hochstetter
Micromachines, 2020, 11, 468
DOI: 10.3390/mi11050468

Label-free isolation of circulating tumor cells in microfluidic devices: Current research and perspectives
Igor Cima, Chay Wen Yee, Florina S. Iliescu, Wai Min Phyo, Kiat Hon Lim, Ciprian Iliescu and Min Han Tan
Biomicrofluidics, 2013, 7
DOI: 10.1063/1.4780062

Sheathless inertial cell focusing and sorting with serial reverse wavy channel structures
Yinning Zhou, Zhichao Ma and Ye Ai
Microsyst Nanoeng, 2018, 4
DOI: 10.1038/s41378-018-0005-6

Recent advances of liquid biopsy: Interdisciplinary strategies toward clinical decision‐making
Han Bao, Li Min, Fanqin Bu, Shutao Wang and Jingxin Meng
Interdisciplinary Medicine, 2023, 1
DOI: 10.1002/INMD.20230021

Combination of inertial focusing and magnetoporetic separation in a novel microdevice
Afshin Shiriny, Morteza Bayareh and Afshin Ahmadi Nadooshan
Korean J. Chem. Eng., 2021, 38, 1686
DOI: 10.1007/s11814-021-0795-3

Mixing enhancement using the aiding and opposing flow effects in curved micro channel
Arees Qamareen, Mubashshir Ahmad Ansari and Shah Shahood Alam
Chemical Engineering and Processing - Process Intensification, 2022, 176, 108945
DOI: 10.1016/j.cep.2022.108945

High-Throughput Blood Plasma Extraction in a Dimension-Confined Double-Spiral Channel
Shaofei Shen, Hanjie Bai, Xin Wang, Henryk Chan, Yanbing Niu, Weiwen Li, Chang Tian and Xiaoping Li
Anal. Chem., 2023, 95, 16649
DOI: 10.1021/acs.analchem.3c03002

Semi-Empirical Estimation of Dean Flow Velocity in Curved Microchannels
Pouriya Bayat and Pouya Rezai
Sci Rep, 2017, 7
DOI: 10.1038/s41598-017-13090-z

Novel approaches in cancer management with circulating tumor cell clusters
Peyman Rostami, Navid Kashaninejad, Khashayar Moshksayan, Mohammad Said Saidi, Bahar Firoozabadi and Nam-Trung Nguyen
Journal of Science: Advanced Materials and Devices, 2019, 4, 1
DOI: 10.1016/j.jsamd.2019.01.006

A particle-capturing and -separating, sheathless chip in series with microfilters and planar interdigital electrodes
Binzhen Zhang, Yangyang Wang, Yunpeng Liu, Huan Li, Wenxuan Zang and Junping Duan
J. Phys. D: Appl. Phys., 2021, 54, 235401
DOI: 10.1088/1361-6463/abe484

An Integrated Inertial-Magnetophoresis Microfluidic Chip Online-Coupled with ICP-MS for Rapid Separation and Precise Detection of Circulating Tumor Cells
Jing Cai, Beibei Chen, Man He, Guolin Yuan and Bin Hu
Anal. Chem., 2024, 96, 14222
DOI: 10.1021/acs.analchem.4c02876

Separation of particles with bacterial size range using the control of sheath flow ratio in spiral microfluidic channel
Jae-Ho Lee, Seung-Ki Lee, Jong-Ho Kim and Jae-Hyoung Park
Sensors and Actuators A: Physical, 2019, 286, 211
DOI: 10.1016/j.sna.2018.12.047

Detection of Circulating Tumor Cells by Fluorescence Microspheres-Mediated Amplification
Jiaxiang Yin, Jinqi Deng, Le Wang, Chang Du, Wei Zhang and Xingyu Jiang
Anal. Chem., 2020, 92, 6968
DOI: 10.1021/acs.analchem.9b05844

Flow study of Dean’s instability in high aspect ratio microchannels
Yu Ching Wong, Cheng Dai, Qingyue Xian, Zhaoxu Yan, Ziyi Zhang and Weijia Wen
Sci Rep, 2023, 13
DOI: 10.1038/s41598-023-44969-9

Combining 3D sidewall electrodes and contraction/expansion microstructures in microchip promotes isolation of cancer cells from red blood cells
Jie Yao, Jingxuan Chen, Xiaodong Cao and Hua Dong
Talanta, 2019, 196, 546
DOI: 10.1016/j.talanta.2018.12.059

Bifurcations and Dynamics in Inertial Focusing of Particles in Curved Rectangular Ducts
Rahil N. Valani, Brendan Harding and Yvonne M. Stokes
SIAM J. Appl. Dyn. Syst., 2022, 21, 2371
DOI: 10.1137/21M1451919

Enhanced particle self-ordering in a double-layer channel
Sheng Yan, Yuxing Li, Qianbin Zhao, Dan Yuan, Guolin Yun, Shi-Yang Tang and Weihua Li
Biomed Microdevices, 2018, 20
DOI: 10.1007/s10544-018-0269-5

Inertial focusing patterns and equilibrium position of particles in symmetric CEA microchannels
Guorui Zhu, Jiaqian Ying, Ziqian Zhang, Yuwen Lu, Xin Shi and Wei Tan
Microfluid Nanofluid, 2022, 26
DOI: 10.1007/s10404-022-02602-7

Novel microfluidic approaches to circulating tumor cell separation and sorting of blood cells: A review
A. Farahinia, W.J. Zhang and I. Badea
Journal of Science: Advanced Materials and Devices, 2021, 6, 303
DOI: 10.1016/j.jsamd.2021.03.005

Rational Design of Materials Interface for Efficient Capture of Circulating Tumor Cells
Yong‐Qiang Li, Bevita K. Chandran, Chwee Teck Lim and Xiaodong Chen
Advanced Science, 2015, 2
DOI: 10.1002/advs.201500118

Circulating tumor cells: Advances in isolation and analysis, and challenges for clinical applications
Ramdane Harouaka, Zhigang Kang, Si-Yang Zheng and Liang Cao
Pharmacology & Therapeutics, 2014, 141, 209
DOI: 10.1016/j.pharmthera.2013.10.004

Tunable particle separation in a hybrid dielectrophoresis (DEP)- inertial microfluidic device
Jun Zhang, Dan Yuan, Qianbin Zhao, Sheng Yan, Shi-Yang Tang, Say Hwa Tan, Jinhong Guo, Huanming Xia, Nam-Trung Nguyen and Weihua Li
Sensors and Actuators B: Chemical, 2018, 267, 14
DOI: 10.1016/j.snb.2018.04.020

Investigation of particle inertial migration in high particle concentration suspension flow by multi-electrodes sensing and Eulerian-Lagrangian simulation in a square microchannel
Tong Zhao, Jiafeng Yao, Kai Liu and Masahiro Takei
Biomicrofluidics, 2016, 10
DOI: 10.1063/1.4946012

Investigation of Leukocyte Viability and Damage in Spiral Microchannel and Contraction-Expansion Array
Thammawit Suwannaphan, Werayut Srituravanich, Achariya Sailasuta, Prapruddee Piyaviriyakul, Suchaya Bhanpattanakul, Wutthinan Jeamsaksiri, Witsaroot Sripumkhai and Alongkorn Pimpin
Micromachines, 2019, 10, 772
DOI: 10.3390/mi10110772

Poly(ethylene oxide) Concentration Gradient-Based Microfluidic Isolation of Circulating Tumor Cells
Yangchang Cheng, Shaohua Zhang, Lili Qin, Junxiang Zhao, Hua Song, Yang Yuan, Jiashu Sun, Fei Tian and Chao Liu
Anal. Chem., 2023, 95, 3468
DOI: 10.1021/acs.analchem.2c05257

Advances in analytical microfluidic workflows for differential cancer diagnosis
Morteza Hasanzadeh Kafshgari and Oliver Hayden
Nano Select, 2023, 4, 1
DOI: 10.1002/nano.202200158

Microfluidic separation device for blood components with lipids and cancer cells
S. Ramya, S. Praveen Kumar, Mohamed Yousuff Caffiyar and N. V. Hemamalini
Microsyst Technol, 2025, 31, 1561
DOI: 10.1007/s00542-024-05793-x

A Simplified Microfluidic Device for Particle Separation with Two Consecutive Steps: Induced Charge Electro-osmotic Prefocusing and Dielectrophoretic Separation
Xiaoming Chen, Yukun Ren, Weiyu Liu, Xiangsong Feng, Yankai Jia, Ye Tao and Hongyuan Jiang
Anal. Chem., 2017, 89, 9583
DOI: 10.1021/acs.analchem.7b02892

A Microfluidic Cell Size/Density Sensor by Resistive Pulse Detection
Jiashu Sun, Yuejun Kang, Erik M. Boczko and Xingyu Jiang
Electroanalysis, 2013, 25, 1023
DOI: 10.1002/elan.201200507

Precise Size-Based Cell Separation via the Coupling of Inertial Microfluidics and Deterministic Lateral Displacement
Nan Xiang, Jie Wang, Qiao Li, Yu Han, Di Huang and Zhonghua Ni
Anal. Chem., 2019, 91, 10328
DOI: 10.1021/acs.analchem.9b02863

Improved zonal chondrocyte production protocol integrating size-based inertial spiral microchannel separation and dynamic microcarrier culture for clinical application
Ching Ann Tee, Zheng Yang, Lu Yin, Yingnan Wu, Jongyoon Han and Eng Hin Lee
Biomaterials, 2019, 220, 119409
DOI: 10.1016/j.biomaterials.2019.119409

The design and fabrication of thermoplastic microfluidic chips with integrated micropillars for particle separation
Mingyong Zhou, Shunquan Jiang, Xueheng Yang, Qiang Li, Bingyan Jiang, Li Zhou and Lu Zhang
Journal of Materials Research and Technology, 2024, 33, 874
DOI: 10.1016/j.jmrt.2024.09.135

Vortex sorting of rare particles/cells in microcavities: A review
Feng Shen, Jie Gao, Jie Zhang, Mingzhu Ai, Hongkai Gao and Zhaomiao Liu
Biomicrofluidics, 2024, 18
DOI: 10.1063/5.0174938

A hybrid dielectrophoretic and hydrophoretic microchip for particle sorting using integrated prefocusing and sorting steps
Sheng Yan, Jun Zhang, Yuan Yuan, George Lovrecz, Gursel Alici, Haiping Du, Yonggang Zhu and Weihua Li
Electrophoresis, 2015, 36, 284
DOI: 10.1002/elps.201400397

High-Throughput Label-Free Isolation of Heterogeneous Circulating Tumor Cells and CTC Clusters from Non-Small-Cell Lung Cancer Patients
Mina Zeinali, Maggie Lee, Arthi Nadhan, Anvya Mathur, Casey Hedman, Eric Lin, Ramdane Harouaka, Max Wicha, Lili Zhao, Nallasivam Palanisamy, Mathias Hafner, Rishindra Reddy, Gregory Kalemkerian, Bryan Schneider, Khaled Hassan, Nithya Ramnath and Sunitha Nagrath
Cancers, 2020, 12, 127
DOI: 10.3390/cancers12010127

Inertial migrations of cylindrical particles in rectangular microchannels: Variations of equilibrium positions and equivalent diameters
Jinghong Su, Xiaodong Chen and Guoqing Hu
Physics of Fluids, 2018, 30
DOI: 10.1063/1.5018714

Efficient fractionation of cellulose nanofibers using spiral microchannel
Xiaojun Wang, Runyu Li, Jinsong Zeng, Zheng Cheng, Bin Wang, Qijun Ding, Wenhua Gao, Kefu Chen and Jun Xu
Cellulose, 2020, 27, 4029
DOI: 10.1007/s10570-020-03072-2

Highly efficient capture and harvest of circulating tumor cells on a microfluidic chip integrated with herringbone and micropost arrays
Peng Xue, Yafeng Wu, Jinhong Guo and Yuejun Kang
Biomed Microdevices, 2015, 17
DOI: 10.1007/s10544-015-9945-x

High-throughput isolation of cancer cells in spiral microchannel by changing the direction, magnitude and location of the maximum velocity
Vahid Omrani, Mohammad Zabetian Targhi, Fatemeh Rahbarizadeh and Reza Nosrati
Sci Rep, 2023, 13
DOI: 10.1038/s41598-023-30275-x