Issue 19, 2020

A laccase-catalysed tyrosine click reaction

Abstract

A laccase-catalysed tyrosine click reaction proceeded between the tyrosine modification reagent N-methyl luminol and tyrosine residues in peptides/proteins. Laccase-catalysed tyrosine-specific modification under mild reaction conditions (shaking at 37 °C) was more efficient than previously reported tyrosine click reactions using hemin, horseradish peroxidase (HRP) or electrochemistry.

Graphical abstract: A laccase-catalysed tyrosine click reaction

Supplementary files

Article information

Article type
Communication
Submitted
28 мар 2020
Accepted
23 апр 2020
First published
01 май 2020

Org. Biomol. Chem., 2020,18, 3664-3668

A laccase-catalysed tyrosine click reaction

S. Sato, K. Nakane and H. Nakamura, Org. Biomol. Chem., 2020, 18, 3664 DOI: 10.1039/D0OB00650E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements