Issue 18, 2001
From the journal:

Chemical Communications

Identification of Tyr58 as the proton donor in the aspartate-α-decarboxylase reaction

S. Adrian Saldanha,†a   Louise M. Birch,†a   Michael E. Webb,a   Brent K. Nabbs,a   Frank von Delft,b   Alison G. Smithc  and  Chris Abell*a  

* Corresponding authors

a University Chemical Laboratory, Lensfield Road, Cambridge, UK
E-mail: ca26@cam.ac.uk

b Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, UK

c Department of Plant Sciences, University of Cambridge, Downing Street, Cambridge, UK

Abstract

The decarboxylation of L-aspartate by E. coliL-aspartate-α-decarboxylase (ADC) is shown to occur with retention of configuration; analysis of the protein structure identifies Tyr58 as the proton donor in the decarboxylation mechanism.

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B106090M
Article type
Communication
Submitted
10 юли 2001
Accepted
30 юли 2001
First published
29 авг 2001

Chem. Commun., 2001, 1760-1761

Permissions

Request permissions

Identification of Tyr58 as the proton donor in the aspartate-α-decarboxylase reaction

S. A. Saldanha, L. M. Birch, M. E. Webb, B. K. Nabbs, F. von Delft, A. G. Smith and C. Abell, Chem. Commun., 2001, 1760 DOI: 10.1039/B106090M

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements