Issue 5, 2024

The role of PAT in the development of telescoped continuous flow processes

Abstract

This review highlights the advantages of incorporating Process Analytical Technologies into continuous flow processes, especially in the context of telescoped multistep flow sequences. Use of FlowIR, in-line UV-vis, online HPLC, online MS and Flow NMR are discussed within this review, with multiple PAT techniques used in conjunction with one another in some instances. PAT is key in ensuring as much information as possible can be gathered during a chemical transformation, with real-time analysis allowing for rapid reaction optimization.

Graphical abstract: The role of PAT in the development of telescoped continuous flow processes

Article information

Article type
Review Article
Submitted
14 дек 2023
Accepted
11 мар 2024
First published
14 мар 2024
This article is Open Access
Creative Commons BY-NC license

React. Chem. Eng., 2024,9, 990-1013

The role of PAT in the development of telescoped continuous flow processes

A. M. Kearney, S. G. Collins and A. R. Maguire, React. Chem. Eng., 2024, 9, 990 DOI: 10.1039/D3RE00678F

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements