Issue 19, 2023

Current status and prospects of MOFs in controlled delivery of Pt anticancer drugs

Abstract

Cancer has become the second leading reason for death in the world. Still, cancer therapy development is exceptionally challenging because the tumor microenvironment is very complex, and individual tumors are very different. In recent years, researchers have found that platinum-based drugs in the form of metal complexes can effectively solve tumor resistance. In this regard, metal–organic frameworks (MOFs) as suitable carriers with high porosity are also exceptional in the biomedical field. Therefore, this article reviews the application of platinum as an anticancer drug and the composite anticancer properties of platinum and MOF materials and prospects for its future development, which provides a new direction for further research in the biomedical field.

Graphical abstract: Current status and prospects of MOFs in controlled delivery of Pt anticancer drugs

Article information

Article type
Perspective
Submitted
09 фев 2023
Accepted
24 мар 2023
First published
24 мар 2023

Dalton Trans., 2023,52, 6226-6238

Current status and prospects of MOFs in controlled delivery of Pt anticancer drugs

J. Chen, Z. Zhang, J. Ma, A. Nezamzadeh-Ejhieh, C. Lu, Y. Pan, J. Liu and Z. Bai, Dalton Trans., 2023, 52, 6226 DOI: 10.1039/D3DT00413A

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