Cubic nano-silver-decorated manganese dioxide micromotors: enhanced propulsion and antibacterial performance

Abstract

The increasing threat of antibiotic-resistant bacterial strains represents the current antibacterial dilemma and requires novel bactericidal treatment to circumvent this problem. In this work, an efficient strategy for killing bacteria using PEDOT/MnO₂@Ag micromotors is reported based on the intense motion-induced convection and excellent sterilization ability of silver (Ag) ions. A distinctive inner surface structure with cubic Ag nanoparticle growth and dispersion in the MnO₂ layer was constructed by simple cathodic co-electrodeposition. Due to the synergistic catalytic reaction of both MnO₂ and Ag, the micromotors can rapidly swim in very low concentrations of hydrogen peroxide (H₂O₂). The antibacterial efficiency of the micromotors was evaluated with the Escherichia coli (E. coli) model. The continuous movement of micromotors, corresponding to violent mass transfer, along with the on-the-fly release of silver ions, greatly enhanced bacteria killing efficacy, with about 14% increase in bacterial death in 0.2% H₂O₂ solution as compared to no motors. Such proposed micromotors could be ideal candidates for combating antibiotic-resistant bacteria in the fields of biomedical and environmental applications.