Application of a rhodium-catalyzed cyclization cycloaddition cascade strategy to the total synthesis of (−)-curcumol

X. X. Zhang; R. Y. Y. Ko; X. Q. Xie; W. P. Qi; P. C. Li; P. Chiu

doi:10.1039/C7QO01150D

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Application of a rhodium-catalyzed cyclization cycloaddition cascade strategy to the total synthesis of (−)-curcumol†

X. X. Zhang,*^a R. Y. Y. Ko,^b X. Q. Xie,^a W. P. Qi,^a P. C. Li^a and P. Chiu

*^b

Author affiliations

* Corresponding authors

^a College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang 310032, P. R. China
E-mail: zhangxx@zjut.edu.cn

^b Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China
E-mail: pchiu@hku.hk

Abstract

A de novo asymmetric total synthesis of (−)-curcumol has been realized, based on a rhodium-catalyzed cyclization–cycloaddition cascade reaction as the key step to construct the tricyclic nucleus.

This article is part of the themed collections: Celebrating Excellence in Research: Women at the Frontiers of Chemistry and Synthetic Approaches to Natural Products via Catalytic Processes

Download options Please wait...

Supplementary files

Article information

DOI: https://doi.org/10.1039/C7QO01150D
Article type: Research Article
Submitted: 23 дек 2017
Accepted: 23 яну 2018
First published: 23 яну 2018

Download Citation

Org. Chem. Front., 2018,5, 1092-1095

Permissions

Request permissions

Application of a rhodium-catalyzed cyclization cycloaddition cascade strategy to the total synthesis of (−)-curcumol

X. X. Zhang, R. Y. Y. Ko, X. Q. Xie, W. P. Qi, P. C. Li and P. Chiu, Org. Chem. Front., 2018, 5, 1092 DOI: 10.1039/C7QO01150D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Organic Chemistry Frontiers

Application of a rhodium-catalyzed cyclization cycloaddition cascade strategy to the total synthesis of (−)-curcumol†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Application of a rhodium-catalyzed cyclization cycloaddition cascade strategy to the total synthesis of (−)-curcumol

Social activity

Search articles by author

Spotlight

Advertisements