Ruthenium-catalyzed 1,2,3-triazole directed intermolecular C–H amidation of arenes with sulfonyl azides

Abstract

Synthesis of 2-(2H-1,2,3-triazole-2-yl)aniline derivatives from 2-aryl-1,2,3-triazoles and sulfonylazides through ruthenium-catalyzed intermolecular C–H amidation is achieved. This reaction provides an environmentally benign protocol for C–N bond formation, producing N₂ gas as the sole byproduct. Yet a number of functionalities are well tolerated, obtaining the desired products in moderate to excellent yields.