Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxideElectronic supplementary information (ESI) available: Fig. S1: X-ray diffraction patterns of (a) [LiAl2(OH)6]Cl·H2O and (b) LDH/Ibuprofen intercalate. See http://www.rsc.org/suppdata/cc/b1/b106465g/
Abstract
A series of pharmaceutically active compounds including diclofenac, gemfibrozil, ibuprofen, naproxen, 2-propylpentanoic acid, 4-biphenylacetic acid and tolfenamic acid can be reversibly intercalated into a layered double hydroxide, initial studies suggest that these materials may have application as the basis of a novel tuneable drug delivery system.
- This article is part of the themed collection: ChemComm 60th Anniversary Historic Papers from the United Kingdom