This review describes the recent advances in different reaction types and catalytic systems for the construction of C–NAr and S–NAr bonds by nitroaromatic reductive cross-coupling.
We present herein an iron-catalyzed direct denitrative chlorination of (hetero)nitroarenes at room temperature under near visible light irradiation.
A reductive and denitrative amination of nitroarenes has been developed, allowing the highly selective synthesis of various di- and triarylamines. The protocol employed synthetically upstream nitroarenes as both the electrophiles and amine sources.
Distinct reactivity and chemoselectives of photoexcited nitroarenes under visible light irradiation such as reductive C–N coupling, anaerobic oxidation, annulation, scaffold diversification via nitrene insertion, etc., are highlighted.
We disclose a novel protocol for arylsilane via a Pd-catalyzed cross-coupling of hexamethyldisilane with nitroarenes, and the products could be easily transformed into aryl halides, homocoupling products, and aryl boron reagents.