Hong-Yu Zhu, Yi-Min Ma, Qian-Sui Gu, Si-Qi Huo, A-Lei Zhang, Fei-Fei Chen and Ke-Quan Chen
Chem. Commun., 2026,62, 9054-9068
Abstract
Amine dehydrogenases (AmDHs) are a versatile class of enzymes that catalyze the reductive amination of carbonyl compounds with amino donors.
Hannah R. Valentino, Liangyu Qian, Jerry M. Parks, Erin E. Drufva, Ada Sedova, Pankti S. Mehta, Mary P. Watson, Richard J. Giannone, Stephanie S. Galanie and Joshua K. Michener
Green Chem., 2025,27, 6283-6292
From themed collection:
Exploring the Frontiers: Unveiling New Horizons in Carbon Efficient Biomass Utilization
Abstract
Aliphatic amino alcohols such as 6-amino-1-hexanol are potential platform chemicals for a variety of advanced materials. Selective enzymatic synthesis from biomass-derived diols could simplify production while minimizing hazards.
Weixi Kong, Biao Li, Qi Zhang, Xuyang Lei, Ke Zheng, Xiaoyang Yue, Yunting Liu and Yanjun Jiang
Green Chem., 2026,28, 8201-8212
From themed collection:
Green Liquids and Solvents
Abstract
Blocking a detrimental helix-to-loop transition by a betaine–acetic acid DES enhances engineered AmDH activity and stability, while immobilization and flow operations further augment these effects, enabling intensified ARA at high substrate loads.
Feodor Belov, Andrea Mildner, Tanja Knaus, Francesco G. Mutti and Jan von Langermann
React. Chem. Eng., 2023,8, 1427-1439
From themed collection:
Biocatalysis & Bioprocessing
Abstract
This study highlights the use of selective crystallization as a downstream-processing concept for amine products from biocatalytic reactions.
Kai Wu, Jinrong Yan, Qinde Liu, Xiaojing Wang, Piaoru Wu, Yiyang Cao, Xiuhong Lu, Yixin Xu, Junhai Huang and Lei Shao
Chem. Sci., 2024,15, 1431-1440
Abstract
The stereoselectivity and thermal stability of imine reductase are manipulated through computational design, based on predicted catalytic mechanisms and subunit interfaces.