Recent advances in the direct synthesis of trifluoromethyl-containing heterocycles from trifluoroacetimidoyl chlorides (TFAICs) and derivatives, including trifluoroacetimidohydrazides (TFAIHs) and CF3–imidoyl sulfoxonium ylides (TFISYs), are systematically summarized and discussed.
Activated carbon fibers, known for their unique physical and chemical properties, are increasingly utilized in diverse industries, including textiles and fabrics, and can serve as ideal supports of heterogeneous palladium catalysts.
Recent advances in the preparation of trifluoromethyl-containing heterocyclics via trifluoromethyl building block strategies over the period from 2019 to the present are systematically summarized and discussed.
DFT calculations show that the difference in reactivity caused by different raw materials (aryl halides/trifluoromethanesulfonate) is due to the different formation rates of intermediates in copper and palladium catalytic cycles.
This review systematically summarizes recent advances in azide-free synthetic methodologies for 1,2,3-triazole construction, with a focus on alternative nitrogen sources including hydrazones, diazo compounds, and nitrite esters/salts.