In this review, we summarize the recent advances in the synthesis of 2-aminophenoxazinone frameworks based on different catalytic approaches and synthetic process routes of 2-aminophenoxazinone compounds.
Tuning copper coordination geometry and catalysis through axial donor variation in bio-inspired phenoxazinone synthase models.
Cr(III), Mn(II), Co(II), Ni(II) and Cu(II) chelates of the hydrazone ligand have been synthesized and their structure have been confirmed. Phenoxazinone synthase like efficacy afforded high activity for Mn(II) complex with TOF number of 169.89 h−1.
Copper(II) complexes of dipica-derivatives were studied as phenoxazinone synthase models and catalyze the oxidative dimerization of o-aminophenol into aminophenoxazinon-3-one in H2O and their rate of reactivity influenced by steric and electronic factors.
A tetranuclear Mn4(II,III,III,II) diamond core complex was synthesised through dioxygen activation, which efficiently mimics both catechol oxidase and phenoxazinone synthase enzymes.