This work reviewed the recent progress in the chemoenzymatic synthesis of human glycans and provides insights into the limitations and perspectives of the current methods.
This review summarises major contributions based on carbohydrate multivalent systems to study their interaction with human lectins.
This work presents a novel series of galectin inhibitors with ferrocene and ruthenium arene motifs. Diferrocene thiodigalactoside exhibited high binding affinity and selectivity for human galectin-1 over human galectin-3.
Nuclear Magnetic Resonance (NMR) has been widely employed to assess diverse features of glycan–protein molecular recognition events.
Glycan microarrays provide a high-throughput platform to rapidly interrogate serum anti-glycan antibodies, identify new biomarkers for a variety of conditions, and analyze the immune system's response to vaccines and other treatments.