Recent advances in the preparation of trifluoromethyl-containing heterocyclics via trifluoromethyl building block strategies over the period from 2019 to the present are systematically summarized and discussed.
Skeletal editing enables atom-level modifications to molecular skeletons. This review highlights advances in single-atom insertions, deletions, and transmutations in (hetero)cyclic systems, offering a comprehensive view on cutting-edge strategies.
We report that substituents on imine carbons of β-diiminate have significant impact on the emission efficiency of their boron complexes and polymers.
Pseudo-MCRs are domino-type one-pot processes that involve combinations of at least three reactants (similarly to normal MCRs) but in which one of them is stoichiometrically duplicated (or more) and hence takes part into two reaction steps (or more).
A variety of 3,5-bis(fluoroalkyl)pyrazoles/pyrazolines were synthesized via an efficient [3 + 2] cycloaddition reaction of di/trifluoromethyl hydrazonoyl bromides with trifluoropropenes.