Amino acid metabolism is essential to homeostasis, immune regulation, and disease. This review highlights natural products that modulate these metabolic pathways and outlines synthetic strategies to enhance their therapeutic potential.
Fluorinated five-membered heterocycles have potent therapeutic activities including antiviral, anti-inflammatory, enzymatic inhibitory, and antimalarial.
Bifidobacterium longum S3 influenced the intestinal barrier and immunity, water channel protein expression, and neurotransmitter and GI active peptide levels by affecting the intestinal barrier and immunity and modulating changes in the levels of fatty acid metabolites, especially LCFAs.
Bifidobacterium bifidum CCFM1359 remodels intestinal nerves, dreduces intestinal inflammation through BDNF-TrkB pathway, and improves intestinal microecology to alleviate intestinal motility disorders (created with BioGDP.com).
Cathartic colon (CC) is a type of slow-transit constipation caused by a patient's long-term use of irritating laxatives. Probiotics play a crucial role in managing constipation.