Engineered plant extracellular vesicles for natural delivery across physiological barriers

Yu Wang, Yifang Wu, Si Shen, Yinyin Liu, Ying Xia, Hongmei Xia, Zili Xie and Yinxiang Xu

Food Funct., 2024, 15, 1737
DOI: 10.1039/D3FO03503D

The Chemopreventive Impact of Diet-Derived Phytochemicals on the Adipose Tissue and Breast Tumor Microenvironment Secretome

Naoufal Akla, Carolane Veilleux and Borhane Annabi

Nutrition and Cancer, 2025, 77, 9
DOI: 10.1080/01635581.2024.2401647

Unveiling protective mechanisms of wild olive (acebuche) oil in retinal pigment epithelial cells with hypertensive phenotype

Álvaro Santana‐Garrido, Claudia Reyes‐Goya, Pablo Espinosa‐Martín, Rosa M. Troya‐Toledo, Helder André, Alfonso Mate and Carmen M. Vázquez

The Journal of Physiology, 2025
DOI: 10.1113/JP287367

Oral Delivery of Ellagic Acid Encapsulated in Milk Exosomes: Sex‐Based Differences in Bioavailability, Urolithin Production, and Gut Microbiota Modulation

María Ángeles Ávila‐Gálvez, María Romo‐Vaquero, Carmen Mazarío‐Gárgoles, Joao Tomé‐Carneiro, María‐Carmen López de las Hazas, Alberto Dávalos, María Victoria Selma, Antonio González‐Sarrías and Juan Carlos Espín

Molecular Nutrition Food Res, 2025, 69
DOI: 10.1002/mnfr.70104

Therapeutic potential of extracellular vesicle-polyphenol nanoplatform in regenerative medicine

Meirui Ma, Qianyi Wu, Tianyou Wang, Yuanyuan Ma, Le Fan, Yiqiao Wang, Liulin Jiang, Zhipeng Gu and Zhichao Hao

Nano Materials Science, 2025
DOI: 10.1016/j.nanoms.2025.05.008

Exosome-Containing Extracellular Vesicles Contribute to the Transport of Resveratrol Metabolites in the Bloodstream: A Human Pharmacokinetic Study

Carlos Eduardo Iglesias-Aguirre, María Ángeles Ávila-Gálvez, María-Carmen López de las Hazas, Alberto Dávalos and Juan Carlos Espín

Nutrients, 2022, 14, 3632
DOI: 10.3390/nu14173632

Ellagic acid and its metabolites urolithins A/B ameliorate most common disease phenotypes in cellular and mouse models for lysosomal storage disorders by enhancing extracellular vesicle secretion

Beatriz Soto-Huelin, Bohdan Babiy, Oscar Pastor, Mario Díaz-García, Ana Toledano-Zaragoza, María Dolores Frutos, Juan Carlos Espín, Francisco A. Tomás-Barberán, Rebeca Busto and María Dolores Ledesma

Neurobiology of Disease, 2023, 182, 106141
DOI: 10.1016/j.nbd.2023.106141

Loading milk exosomes with urolithins boosts their delivery to the brain: Comparing the activity of encapsulated vs. free urolithins in SH-SY5Y neuroblastoma cells

María Ángeles Ávila-Gálvez, Salvador Romero-Reyes, María del Carmen López de las Hazas, Andrea del Saz-Lara, Alberto Dávalos, Juan Carlos Espín and Antonio González-Sarrías

Food Bioscience, 2024, 61, 104888
DOI: 10.1016/j.fbio.2024.104888

Enhanced brain delivery and antiproliferative activity of resveratrol using milk-derived exosomes

María Ángeles Ávila-Gálvez, Beatriz Garay-Mayol, Juan Antonio Giménez-Bastida, María del Carmen López de las Hazas, Carmen Mazarío-Gárgoles, Maria Alexandra Brito, Alberto Dávalos, Juan Carlos Espín and Antonio González-Sarrías

Journal of Agriculture and Food Research, 2024, 18, 101370
DOI: 10.1016/j.jafr.2024.101370

Perspective on the Coevolutionary Role of Host and Gut Microbiota in Polyphenol Health Effects: Metabotypes and Precision Health

Juan Carlos Espín, María Paula Jarrín‐Orozco, Leire Osuna‐Galisteo, María Ángeles Ávila‐Gálvez, María Romo‐Vaquero and María Victoria Selma

Molecular Nutrition Food Res, 2024, 68
DOI: 10.1002/mnfr.202400526

From bugs to brain: unravelling the GABA signalling networks in the brain–gut–microbiome axis

Delia Belelli, Jeremy J Lambert, Murphy Lam Yim Wan, Ana Rita Monteiro, David J Nutt and Jerome D Swinny

Brain, 2025, 148, 1479
DOI: 10.1093/brain/awae413