A review of the capacity of xylooligosaccharides to modulate gut microbiota and promote health

Natalia-María Nogueira-Prieto, Carmen Ansín-Vallejo, Manuel Becerra-Fernández and María-Isabel González-Siso

Food Funct., 2025, 16, 4654
DOI: 10.1039/D5FO00169B

Multi-omics analysis reveals that agaro-oligosaccharides with different degrees of polymerization alleviate colitis in mice by regulating intestinal flora and arginine synthesis

Long Yuan, Chunhui Liu, Bolun Li, Sai Wang, Jianan Sun and Xiangzhao Mao

Food Funct., 2024, 15, 10628
DOI: 10.1039/D4FO03650F

Mechanocatalytic depolymerization of hemicellulose to low molecular weight oligosaccharides over an aquivion ionomer

Jonathan Fabian Sierra Cantor, Karine De Oliveira Vigier, Gilles Labat, Denilson Da Silva Perez and François Jérôme

RSC Sustainability, 2023, 1, 446
DOI: 10.1039/D3SU00028A

Galactooligosaccharide or 2′-Fucosyllactose Modulates Gut Microbiota and Inhibits LPS/TLR4/NF-κB Signaling Pathway to Prevent DSS-Induced Colitis Aggravated by a High-Fructose Diet in Mice

Tao Chen, Chuqing Wang, Chenxi Nie, Xiaojin Yuan, Aobai Tu and Juxiu Li

J. Agric. Food Chem., 2023, 71, 9349
DOI: 10.1021/acs.jafc.2c08814

Alginate Oligosaccharides Enhance Gut Microbiota and Intestinal Barrier Function, Alleviating Host Damage Induced by Deoxynivalenol in Mice

Jinqiu Mi, Yaoyi Tong, Qiyue Zhang, Qingfeng Wang, Yanwei Wang, Yue Wang, Gang Lin, Qiugang Ma, Tiantian Li and Shimeng Huang

The Journal of Nutrition, 2024, 154, 3190
DOI: 10.1016/j.tjnut.2024.09.031

Human Milk Oligosaccharides Modulating Inflammation in Infants, Adults, and Older Individuals—From Concepts to Applications

Robert Häsler, Marta Hanna Mikš, Danica Bajic, Buket Soyyilmaz, Igor Bendik, Vincent J van Buul, Robert E Steinert and Ateequr Rehman

Advances in Nutrition, 2025, 16, 100433
DOI: 10.1016/j.advnut.2025.100433

Exploring the potential of xylooligosaccharides as prebiotics: insights from CAZymes families and their emerging health benefits

Cilia Bouiche, Aicha Asma Houfani, Zahra Azzouz, Lamia Taouzinet, Lamia Medouni-Haroune, Meriem Amrane-Abider and Khodir Madani

Biologia, 2023, 78, 1789
DOI: 10.1007/s11756-023-01440-4

Xylo‐oligosaccharides improve functional constipation by targeted enrichment of Bifidobacterium

Wanya Yi, Qinyue Wang, Yuzheng Xue, Hong Cao, Ruijuan Zhuang, Dan Li, Jiai Yan, Ju Yang, Yanping Xia and Feng Zhang

Food Science & Nutrition, 2024, 12, 1119
DOI: 10.1002/fsn3.3827

Preparation and structure characterization of a natural acetylated fructooligosaccharide from Polygonatum sibiricum and its alleviative effect on colitis by inhibiting NLRP3 pathway

Shengchen Ding, Jun Chen, Guangming Chen, Weiyi Tian, Junping Zheng, Haiming Hu, Lu Cao, Xiaowei Yao, Baifei Hu and Hongtao Liu

Journal of Functional Foods, 2024, 113, 106027
DOI: 10.1016/j.jff.2024.106027

An exploration of alginate oligosaccharides modulating intestinal inflammatory networks via gut microbiota

Zhikai Zhang, Xuejiang Wang and Feng Li

Front. Microbiol., 2023, 14
DOI: 10.3389/fmicb.2023.1072151

A Recombinant Alginate Lyase Algt1 with Potential in Preparing Alginate Oligosaccharides at High-Concentration Substrate

Qingping Liang, Youtao Huang, Zhemin Liu, Mengshi Xiao, Xinmiao Ren, Tianhong Liu, Hongyan Li, Dongxing Yu, Ying Wang and Changliang Zhu

Foods, 2023, 12, 4039
DOI: 10.3390/foods12214039

The source, extraction, purification, physiological function, and application of stachyose in the food industry

Xitao Ta, Botao Wang, Junying Bai, Jielin Yu, Hangyu Chen and Chen Wang

Food Chemistry, 2024, 461, 140791
DOI: 10.1016/j.foodchem.2024.140791

Recent advances in prebiotics: Classification, mechanisms, and health applications

Sajid Ali, Muhammad Hamayun, Muhammad Siraj, Sumera Afzal Khan, Ho-Youn Kim and Bokyung Lee

Future Foods, 2025, 12, 100680
DOI: 10.1016/j.fufo.2025.100680

A critical review on inflammatory bowel diseases risk factors, dietary nutrients regulation and protective pathways based on gut microbiota during recent 5 years

Pengkui Xia, Tao Hou, Hong Jin, Yaqi Meng, Jing Li, Fuchao Zhan, Fang Geng and Bin Li

Critical Reviews in Food Science and Nutrition, 2024, 64, 8805
DOI: 10.1080/10408398.2023.2204147

Safety evaluation of Bifidobacterium pseudocatenulatum E−0810 and its synbiotic formulation with xylooligosaccharides in alleviating LPS-induced inflammation in intestinal epithelial cells

Zhenyu Yang, Xinyu Wang, Shan Wu, Yu Xin, Peng Du, Guofang Zhang, Chun Li and Libo Liu

Food Bioscience, 2025, 71, 107069
DOI: 10.1016/j.fbio.2025.107069

Neokestose suppresses the increase in plasma glucose caused by oral administration of sucrose in a streptozotocin‑induced diabetic rat

Kanta Sato, Saori Deguchi, Noriaki Nagai, Tetsushi Yamamoto, Kuniko Mitamura and Atsushi Taga

Sci Rep, 2024, 14
DOI: 10.1038/s41598-024-67458-z

Natural approaches for the management of ulcerative colitis: evidence of preclinical and clinical investigations

Rudra Narayan Subudhi, Neelam Poonia, Dilpreet Singh and Vimal Arora

Nat. Prod. Bioprospect., 2024, 14
DOI: 10.1007/s13659-024-00463-x

Active ingredients in waste of distillers’ grains and their resource utilization

Bin Dong, Yijie Wang, Lili Han, Guirong Cui, Yuna Wang and Zhiwei Su

Rev Environ Sci Biotechnol, 2025, 24, 191
DOI: 10.1007/s11157-025-09718-6

Optimization of microwave-ultrasound assisted extraction of oligosaccharides from pea seeds and its probiotic proliferative activity

Ruoqi Zhao, Mingwu Qiao, Yan Ma, Qian Li, Ning Li, Xianqing Huang, Yongxia Cheng and Lianjun Song

J Food Sci Technol, 2025
DOI: 10.1007/s13197-025-06320-0

Advances in Lactic Acid Bacteria and Their Metabolites in Fermented Foods: Mechanisms of Food Quality Enhancement, Gut Microbiota modulation, and Future Prospects

Jianwei Zang, Tao Lin, Chang Xu, Yihan Lin, Kai Ma, Changliang Zhang, Xin Rui, Dan Gan and Wei Li

Food Reviews International, 2025, 1
DOI: 10.1080/87559129.2025.2524405

Prebiotics Progress Shifts in the Intestinal Microbiome That Benefits Patients with Type 2 Diabetes Mellitus

Luis Vitetta, Nick N. Gorgani, Gemma Vitetta and Jeremy D. Henson

Biomolecules, 2023, 13, 1307
DOI: 10.3390/biom13091307

Effects of soybean oligosaccharides instead of glucose on growth, digestion, antioxidant capacity and intestinal flora of crucian carp cultured in biofloc system

Zongsheng Qiu, Jianhua Zhao, Qiaohua Luo, Rendong Qian, Xiaowen Lin and Qiyou Xu

Aquaculture Reports, 2023, 29, 101512
DOI: 10.1016/j.aqrep.2023.101512

Comparative study the alleviated effects of various oligosaccharides on colitis in mice

Lijie Wang, Yue Pan, Xiaoning Zhang and Xuejiao Ren

International Immunopharmacology, 2024, 135, 112293
DOI: 10.1016/j.intimp.2024.112293

Oral colon-targeted responsive chitosan/pectin-based nanoparticles propels the application of tofacitinib in colitis therapy

Chunfei Wu, Chuanlin Bi, Geun-soo Kim, Zizhen Yang, Shuao Li, Tong Dai, Xiaoyu Wu, Jiaojiao Tan, Ningning He and Shangyong Li

Sci Rep, 2025, 15
DOI: 10.1038/s41598-024-84322-2

Alginate oligosaccharide structures differentially affect DSS-induced colitis in mice by modulating gut microbiota

Shuang Lu, Kai Na, Jiani Wei, Ting Tao, Li Zhang, Ying Fang, Xiangyu Li and Xiaohua Guo

Carbohydrate Polymers, 2023, 312, 120806
DOI: 10.1016/j.carbpol.2023.120806

Enzymatic synthesis of stachyose-derived fatty acid mono-esters, the evaluation of their surface and interfacial properties and the capacity of certain derived emulsions to deliver resveratrol

Mengfei Xie, Chun Qing, Jiankang Yi, Yongle Chen, Zhijian Yang, Martin G. Banwell and Ping Lan

Food Chemistry, 2025, 472, 142948
DOI: 10.1016/j.foodchem.2025.142948

Alginate oligosaccharide-mediated butyrate-HIF-1α axis improves skin aging in mice

Ting Gao, Yixuan Li, Xiaoyu Wang and Fazheng Ren

Journal of Pharmaceutical Analysis, 2024, 14, 100911
DOI: 10.1016/j.jpha.2023.12.001

The Effects of Synbiotics on Dextran-Sodium-Sulfate-Induced Acute Colitis: The Impact of Chitosan Oligosaccharides on Endogenous/Exogenous Lactiplantibacillus plantarum

Yunjiao Zhao, Liangyu Xue, Shunqin Li, Tao Wu, Rui Liu, Wenjie Sui and Min Zhang

Foods, 2023, 12, 2251
DOI: 10.3390/foods12112251

The enhancement mechanism of adding stachyose to Lactiplantibacillus plantarum SS-128 in the probiotic/prebiotic combination biopreservation in salmon

Taige Liu, Jingqi Shen, Yilin Qian, Yuanhui Zhao, Xianghong Meng, Zunying Liu and Fei Jia

LWT, 2024, 205, 116526
DOI: 10.1016/j.lwt.2024.116526

Dietary interventions to augment immunity: A bibliometric analysis

Zhipeng Zheng, Ruoting Hou, Shaoling Lin, Natthida Sriboonvorakul and Jiamiao Hu

Journal of Functional Foods, 2024, 123, 106625
DOI: 10.1016/j.jff.2024.106625

Supplementation of citrus pectin with whole-cell pectinase PG5 on Pichia pastoris promotes recovery of colitis and enhances intestinal barrier function in DSS-treated mice

Li Zhang, Jing Ren, Tianfei Yu, Yuanrong Li, Yanshun Li, Shuang Lu and Xiaohua Guo

International Journal of Biological Macromolecules, 2024, 264, 130476
DOI: 10.1016/j.ijbiomac.2024.130476

Nondigestible stachyose binds membranous HSP90β on small intestinal epithelium to regulate the exosomal miRNAs: A new function and mechanism

Ting Li, Yueyue Liu, Tianchi Duan, Chao Guo, Bin Liu, Xiuqiong Fu, Lu Wang, Xiaoyuan Wang, Xinyue Dong, Chennan Wang, Yalong Lu, Yu Wang, Lin Shi, Honglei Tian and Xingbin Yang

Cell Metabolism, 2025, 37, 345
DOI: 10.1016/j.cmet.2024.10.012

Potential of Dendrobium officinale oligosaccharides to alleviate chronic colitis by modulating inflammation and gut microbiota

Dong-Cheng Shi, Pei-Yi Wang, Lei Xu, Hua Zhu, Wang-Yue Zhang, Qi-Yong Wu, Ting-Ting Bu, Bao-Ming Tian, Pei-Long Sun and Ming Cai

Food & Medicine Homology, 2025, 2, 9420077
DOI: 10.26599/FMH.2025.9420077

A comprehensive review of synbiotics: an emerging paradigm in health promotion and disease management

Sulhee Lee, Sang-Pil Choi, Hak-Jong Choi, Huijin Jeong and Young-Seo Park

World J Microbiol Biotechnol, 2024, 40
DOI: 10.1007/s11274-024-04085-w

Limosilactobacillus Fermentun ZS09 Can Improve Antibiotic-Induced Motor Dysfunction in Mice by Regulating the Brain–Gut Functions

Yang Yang, Yuanji Zhao, Huan Lei and Xiaohong Tan

JIR, 2024, Volume 17, 10093
DOI: 10.2147/JIR.S486018