Design, synthesis andin vitroevaluation of the hybrids of oxindolylidene and imidazothiazolotriazine as efficient antiproliferative agents

Alexei N. Izmest’ev, Lada V. Anikina, Igor E. Zanin, Natalya G. Kolotyrkina, Ekaterina S. Izmalkova, Angelina N. Kravchenko and Galina A. Gazieva

New J. Chem., 2022, 46, 11632
DOI: 10.1039/D2NJ01454H

Tandem Michael addition/elimination – novel reactivity of pyridinium ylides in reaction with electron-deficient alkenes

Alexei N. Izmest'ev, Vladimir A. Motornov, Dmitry B. Vinogradov, Sema L. Ioffe, Angelina N. Kravchenko and Galina A. Gazieva

Org. Chem. Front., 2022, 9, 4998
DOI: 10.1039/D2QO00911K

A new reversible transformation of oxindolylidene derivatives of imidazothiazolotriazine into 3-[(imidazotriazin-3-yl)thio]-2-oxoquinoline-4-carboxylates

Alexei N. Izmest'ev, Angelina N. Kravchenko and Galina A. Gazieva

Org. Biomol. Chem., 2023, 21, 1827
DOI: 10.1039/D2OB02242G

Recognition of arylmethylidene derivatives of imidazothiazolotriazinones as novel tubulin polymerization inhibitors

Alexei N. Izmest'ev, Elena V. Svirshchevskaya, Sergey B. Akopov, Angelina N. Kravchenko and Galina A. Gazieva

RSC Med. Chem., 2024, 15, 1258
DOI: 10.1039/D4MD00027G

Regioselective synthesis of new imidazo[4,5‐e][1,3]thiazino[2,3‐c][1,2,4]triazines via reaction of imidazo[4,5‐e][1,2,4]triazinethiones with ethyl phenylpropiolate

Dmitry B. Vinogradov, Alexei N. Izmest'ev, Angelina N. Kravchenko, Natalya G. Kolotyrkina and Galina A. Gazieva

Journal of Heterocyclic Chem, 2024, 61, 137
DOI: 10.1002/jhet.4753

A regioselective synthesis of imidazothiazolotriazines based on the cyclization of imidazotriazinethiones with phenacyl bromides

Dmitry B. Vinogradov, Alexei N. Izmest’ev, Angelina N. Kravchenko and Galina А. Gazieva

Chem Heterocycl Comp, 2022, 58, 524
DOI: 10.1007/s10593-022-03123-5

Design, Synthesis, Docking, 2D‐QSAR Modelling, Anticancer and Antioxidant Evaluation of Some New Azo‐Compounds Derivatives and Investigation of Their Fluorescence Properties

Eman O. Hamed, Doaa A. Elsayed, Mohamed G. Assy and Wesam S. Shehab

ChemistrySelect, 2022, 7
DOI: 10.1002/slct.202202534

Unveiling ortho-phenolic Mannich ciprofloxacin-chalcone conjugates with potential antineoplastic activity: synthesis, mechanistic study, in silico docking and molecular dynamic simulation

Islam M. Abdel-Rahman, Mohamed Abdel-Aziz, Heba Ali Hassan, Dalia H. Abu-Baih, Mohamed badr, Moustafa Fathy, Ibrahim M. Salem, Tarek S. Ibrahim, Alaa M. Hayallah and GamalEl-Din A. Abuo-Rahma

European Journal of Medicinal Chemistry, 2025, 296, 117891
DOI: 10.1016/j.ejmech.2025.117891

Synthesis, Structure and Stereochemistry of Dispirocompounds Based on Imidazothiazolotriazine and Pyrrolidineoxindole

Alexei N. Izmest’ev, Valentina A. Karnoukhova, Alexander A. Larin, Angelina N. Kravchenko, Leonid L. Fershtat and Galina A. Gazieva

IJMS, 2022, 23, 13820
DOI: 10.3390/ijms232213820

Synthesis of 7-oxindolylidene-3a,9a-diphenylimidazothiazolo[2,3-c][1,2,4]triazines by skeletal rearrangement of their [3,2-b]-fused isomers

Alexei N. Izmest'ev, Angelina N. Kravchenko and Galina A. Gazieva

Mendeleev Communications, 2022, 32, 678
DOI: 10.1016/j.mencom.2022.09.037

Synthesis, Reactivity, and Applications of 4-Amino-3-Thioxo/Hydrazino-6-Substituted-1,2,4-Triazin-5-Ones and Their Derivatives: A Review

Nawaa Ali H. Alshammari and Dina A. Bakhotmah

Polycyclic Aromatic Compounds, 2023, 43, 1107
DOI: 10.1080/10406638.2022.2025863

The Chemo- and Regioselectivity of the Cyclization of Thiosemicarbazides with Haloacetic Acids and their Derivatives

Alexei N. Izmest’ev, Andrey А. Streltsov, Angelina N. Kravchenko and Galina А. Gazieva

Chem Heterocycl Comp, 2022, 58, 483
DOI: 10.1007/s10593-022-03117-3

Synthesis of new heterylmethylidene derivatives of isomeric imidazo[4,5-e]thiazolo-fused [1,2,4]triazines

Maksim E. Lugovoi, Alexei N. Izmest’ev, Natalya G. Kolotyrkina, Ekaterina S. Izmalkova, Angelina N. Kravchenko and Galina A. Gazieva

Mendeleev Communications, 2024, 34, 558
DOI: 10.1016/j.mencom.2024.06.029

Recent updates on 1,2,3‐, 1,2,4‐, and 1,3,5‐triazine hybrids (2017–present): The anticancer activity, structure–activity relationships, and mechanisms of action

Gaoli Dong, Yingchun Jiang, Feng Zhang, Fengyun Zhu, Junna Liu and Zhi Xu

Archiv der Pharmazie, 2023, 356
DOI: 10.1002/ardp.202200479

Synthesis of S-substituted 5-sulfonylmethyl(ethyl)-1,3,4-thiadiazol-2-amines

Sergei A. Serkov, Natalya V. Sigay, Natalya N. Kostikova, Aleksander E. Fedorov, Anton P. Tyurin and Galina A. Gazieva

Chem Heterocycl Comp, 2022, 58, 514
DOI: 10.1007/s10593-022-03121-7

5-Arylmethylidene-2-iminothiazolidin-4-ones in the synthesis of novel dispiro-fused oxindolepyrrolidineiminothiazolidinones

Alexei N. Izmest’ev, Andrey A. Streltsov, Angelina N. Kravchenko and Galina A. Gazieva

Chem Heterocycl Comp, 2023, 59, 309
DOI: 10.1007/s10593-023-03198-8

Synthesis of imidazo[4,5-e][1,3]thiazino[2,3-c][1,2,4]triazines via a base-induced rearrangement of functionalized imidazo[4,5-e]thiazolo[2,3-c][1,2,4]triazines

Dmitry B Vinogradov, Alexei N Izmest’ev, Angelina N Kravchenko, Yuri A Strelenko and Galina A Gazieva

Beilstein J. Org. Chem., 2023, 19, 1047
DOI: 10.3762/bjoc.19.80

CuO nanoparticles for green synthesis of significant anti-Helicobacter pylori compounds with in silico studies

Wesam S. Shehab, Doaa A. Elsayed, Atef M. Abdel Hamid, Mohamed G. Assy, Samar M. Mouneir, Eman O. Hamed, Sahar M. Mousa and Gehan T. El-Bassyouni

Sci Rep, 2024, 14
DOI: 10.1038/s41598-024-51708-1

Synthesis, Reactivity, and Anticancer Activity Evaluation of 4‐Amino‐3‐Mercapto‐6‐Methyl‐1,2,4‐Triazin‐5(4H)‐One Derivatives

Nawaa Ali H. Alshammari, Dina A. Bakhotmah and Michael G. Gardiner

ChemistrySelect, 2023, 8
DOI: 10.1002/slct.202300735

The synthesis and study of antimicrobial activity of 5-oxo-1-(thiazol-2-yl)pyrrolidine-3-carboxylic acids

Sergei A. Serkov, Natalya N. Kostikova, Natalya V. Sigay, Anton P. Tyurin, Natalya G. Kolotyrkina and Galina A. Gazieva

Chem Heterocycl Comp, 2024, 60, 365
DOI: 10.1007/s10593-024-03348-6

A 1,3-dipolar cycloaddition of azomethine ylides to imidazo[4,5-e]thiazolo[2,3-c][1,2,4]triazine oxindolylidene derivatives in the synthesis of novel spirooxindole derivatives

Alexei N. Izmest’ev, Angelina N. Kravchenko and Galina A. Gazieva

Chem Heterocycl Comp, 2023, 59, 594
DOI: 10.1007/s10593-023-03238-3