Preventive effects of turmeric against HFD/STZ-induced type 2 diabetes in mice by activating IRS1/PI3K/Akt signaling in association with gut microbiota metabolism

Chengcheng Yang, Yao Du, Lusha Wei, Zhengwei Tan, Ting Zhou, Lulu Wang, Xingbin Yang and Yan Zhao

Food Funct., 2025, 16, 3613
DOI: 10.1039/D5FO01001B

Modulation of hyperglycemia, insulin resistance responses and gut microbiota composition in type 2 diabetic mice by capsicum residue soluble dietary fiber

Yaxing Feng, Wenxiu Wang, Xiangyun Liu, Fengjuan Wang, Yuwei Dong, Qianyun Ma and Jianfeng Sun

Food Funct., 2025, 16, 8021
DOI: 10.1039/D5FO01390A

Latilactobacillus sakei QC9 alleviates hyperglycaemia in high-fat diet and streptozotocin-induced type 2 diabetes mellitus mice via the microbiota–gut–liver axis

Mengling Chen, Pengyuan Pan, Hongyan Zhang, Rao Li, Dayong Ren and Bin Jiang

Food Funct., 2024, 15, 8008
DOI: 10.1039/D4FO02316A

Jerusalem artichoke inulin supplementation ameliorates hepatic lipid metabolism in type 2 diabetes mellitus mice by modulating the gut microbiota and fecal metabolome

Jianpeng Li, Siqiang Jia, Chao Yuan, Bin Yu, Zheng Zhang, Meng Zhao, Pengfei Liu, Xia Li and Bo Cui

Food Funct., 2022, 13, 11503
DOI: 10.1039/D2FO02051C

Lactobacillus plantarum SHY130 isolated from yak yogurt attenuates hyperglycemia in C57BL/6J mice by regulating the enteroinsular axis

Guangqi Wang, Jiajia Song, Yechuan Huang, Xueqiong Li, Hongwei Wang, Yu Zhang and Huayi Suo

Food Funct., 2022, 13, 675
DOI: 10.1039/D1FO02387J

Evaluation of Hypoglycemic and Antioxidant Activities of Soybean Meal Products Fermented by Lactobacillus plantarum FPS 2520 and Bacillus subtilis N1 in Rats Fed with High-Fat Diet

Chung-Hsiung Huang, Chun-Lung Chen, Chen-Che Shieh, Shun-Hsien Chang and Guo-Jane Tsai

Metabolites, 2022, 12, 442
DOI: 10.3390/metabo12050442

Barnesiella intestinihominis improves gut microbiota disruption and intestinal barrier integrity in mice with impaired glucose regulation

Xiaojia Liu, Ling Wang, Bing Huang, Yi Jiao, Yaqun Guan and Rebiya Nuli

Front. Pharmacol., 2025, 16
DOI: 10.3389/fphar.2025.1635579

Lactiplantibacillus plantarum: a Natural Ally in Combating Type 2 Diabetes Mellitus and Related Metabolic Disorders

Wenqi Wu, Zhibin Wang, Lina Ding, Yikun Zhang, Kaihui Ma, Hongsheng Li, Yanli Hou and Wenyu Ding

Probiotics & Antimicro. Prot., 2025
DOI: 10.1007/s12602-025-10729-6

The Effect of Probiotic Supplements on Metabolic Parameters of People with Type 2 Diabetes in Greece—A Randomized, Double-Blind, Placebo-Controlled Study

Eva Zikou, Nikolas Dovrolis, Charilaos Dimosthenopoulos, Maria Gazouli and Konstantinos Makrilakis

Nutrients, 2023, 15, 4663
DOI: 10.3390/nu15214663

Novel Insight into the Effect of Probiotics in the Regulation of the Most Important Pathways Involved in the Pathogenesis of Type 2 Diabetes Mellitus

Farzaneh Hasanian-Langroudi, Asghar Ghasemi, Mehdi Hedayati, Seyed Davar Siadat and Maryam Tohidi

Probiotics & Antimicro. Prot., 2024, 16, 829
DOI: 10.1007/s12602-023-10056-8

Oral supplementation with lactic acid bacteria improve the intestinal epithelial barrier and gut microbiota of broiler chicks to alleviate Salmonella Enteritidis infection

Yuting Yang, Jiajun Hong, Zheng Zhang, Minghao Zheng, Jingang Zhao, Xiaowei Fang, Xiongyan Liang, Jing Liu, Yuying Yang, Guangming Tian and Chun Fang

Poultry Science, 2024, 103, 104385
DOI: 10.1016/j.psj.2024.104385

Probiotics alleviate painful diabetic neuropathy by modulating the microbiota–gut–nerve axis in rats

Ye Jiang, Jing Yang, Min Wei, Jiayin Shou, Shixiong Shen, Zhuoying Yu, Zixian Zhang, Jie Cai, Yanhan Lyu, Dongsheng Yang, Yongzheng Han, Jinpiao Zhu, Zhigang Liu, Daqing Ma, Guo-gang Xing and Min Li

J Neuroinflammation, 2025, 22
DOI: 10.1186/s12974-025-03352-3

Lactiplantibacillus plantarum Ln4 attenuates streptozotocin and high-fat diet-induced Type-2 diabetes

Rachit Sood, Kritika, Sanjay and Hae-Jeung Lee

Journal of Functional Foods, 2026, 138, 107219
DOI: 10.1016/j.jff.2026.107219

Precision Microbiome Modulation: Exploring Lactobacillus spp. as A Targeted Strategy for Type 2 Diabetes Management

Ann Sze Cheah, Ji Wei Tan, Faizul Jaafar and Wendy Wai Yeng Yeo

Curr Nutr Rep, 2026, 15
DOI: 10.1007/s13668-026-00739-3

Fu Brick Tea Manages HFD/STZ-Induced Type 2 Diabetes by Regulating the Gut Microbiota and Activating the IRS1/PI3K/Akt Signaling Pathway

Bangran Qi, Daoyuan Ren, Ting Li, Pengfei Niu, Xiangnan Zhang, Xingbin Yang and Jianbo Xiao

J. Agric. Food Chem., 2022, 70, 8274
DOI: 10.1021/acs.jafc.2c02400

Lactiplantibacillusplantarum HM-P2 influences gestational gut microbiome and microbial metabolism

Bin Liu, Zhenzhen Zhang, Junying Zhao, Xianping Li, Yaru Wang, Lu Liu, Weicang Qiao and Lijun Chen

Front. Nutr., 2024, 11
DOI: 10.3389/fnut.2024.1489359

Gut Microbiota and Antidiabetic Drugs: Perspectives of Personalized Treatment in Type 2 Diabetes Mellitus

Wenhui Liu, Zhiying Luo, Jiecan Zhou and Bao Sun

Front. Cell. Infect. Microbiol., 2022, 12
DOI: 10.3389/fcimb.2022.853771

Microbiota: A potential orchestrator of antidiabetic therapy

Bingyao Liu, Linlin Zhang, Hang Yang, Hongting Zheng and Xiaoyu Liao

Front. Endocrinol., 2023, 14
DOI: 10.3389/fendo.2023.973624

Gut bacteria: an etiological agent in human pathological conditions

Md Minarul Islam, Nasir Uddin Mahbub, Seong-Tshool Hong and Hea-Jong Chung

Front. Cell. Infect. Microbiol., 2024, 14
DOI: 10.3389/fcimb.2024.1291148

Bacillus sp. DU-106 ameliorates type 2 diabetes by modulating gut microbiota in high-fat-fed and streptozotocin-induced mice

Jing Yan, Junjian Li, Qiuyan Xue, Shiqing Xie, Jinjin Jiang, Pan Li and Bing Du

Journal of Applied Microbiology, 2022, 133, 3126
DOI: 10.1111/jam.15773

Characteristics of the Serum Microbiota and Circulating Metabolites in Cynomolgus Monkeys With Spontaneous Type 2 Diabetes Mellitus

Chaoyang Tian, Qunhui Yang, Haizhou Lv and Feng Yue

J of Medical Primatology, 2024, 53
DOI: 10.1111/jmp.12738

Effects of Lactobacillus supplementation on glycemic and lipid indices in overweight or obese adults: A systematic review and meta-analysis

Xudong Qiu, Qiong Wu, Wenyan Li, Kairan Tang and Jing Zhang

Clinical Nutrition, 2022, 41, 1787
DOI: 10.1016/j.clnu.2022.06.030

Antihyperglycemic activity of L-norvaline and L-arginine in high-fat diet and streptozotocin-treated male rats

Hayarpi Javrushyan, Edita Nadiryan, Anna Grigoryan, Nikolay Avtandilyan and Alina Maloyan

Experimental and Molecular Pathology, 2022, 126, 104763
DOI: 10.1016/j.yexmp.2022.104763

Effects of Lactoferrin and Lactobacillus Supplementation on Immune Function, Oxidative Stress, and Gut Microbiota in Kittens

Hao Dong, Weiwei Wang, Qianqian Chen, Xiaohan Chang, Longjiao Wang, Shuxing Chen, Lishui Chen, Ran Wang, Shaoyang Ge and Wei Xiong

Animals, 2024, 14, 1949
DOI: 10.3390/ani14131949

The Antidiabetic Potential of Probiotics: A Review

Shiming Li, Zichao Liu, Qi Zhang, Dan Su, Pengjie Wang, Yixuan Li, Wenbiao Shi and Qian Zhang

Nutrients, 2024, 16, 2494
DOI: 10.3390/nu16152494

Positive effects of Epigallocatechin-3-gallate (EGCG) intervention on insulin resistance and gut microbial dysbiosis induced by bisphenol A

Xiang Li, Yunhui Zhang, Congying Zhao, Bowei Zhang, Bo Peng, Yan Zhang, Jin Wang and Shuo Wang

Journal of Functional Foods, 2022, 93, 105083
DOI: 10.1016/j.jff.2022.105083

The ameliorative effect of probiotics on diet-induced lipid metabolism disorders: A review

Yu Wang, Zhiyi Ai, Xinyue Xing, Yuling Fan, Yue Zhang, Bo Nan, Xia Li, Yuhua Wang and Jingsheng Liu

Critical Reviews in Food Science and Nutrition, 2024, 64, 3556
DOI: 10.1080/10408398.2022.2132377

Targeted Therapy for Gut Microbiota: Candidates for a Novel Strategy to Ameliorate Type 2 Diabetes Mellitus

Jiangyan Wang, Yaofei Wei, Dongmian Chen, Xia Li, Hao Zhang, Shuo Feng, Shenghua Lu, Juan Yang, Qi Zeng, Xingxiang He and Lei Wu

Microbial Biotechnology, 2025, 18
DOI: 10.1111/1751-7915.70283

The Role and Mechanism of Probiotics Supplementation in Blood Glucose Regulation: A Review

Xinyu Shen, Chunmin Ma, Yang Yang, Xiaofei Liu, Bing Wang, Yan Wang, Guang Zhang, Xin Bian and Na Zhang

Foods, 2024, 13, 2719
DOI: 10.3390/foods13172719

The benefits of Lactiplantibacillus plantarum: From immunomodulator to vaccine vector

Joshua Tobias, Stefan Heinl, Kristina Dendinovic, Ajša Ramić, Anna Schmid, Catherine Daniel and Ursula Wiedermann

Immunology Letters, 2025, 272, 106971
DOI: 10.1016/j.imlet.2025.106971

Anti-oxidative stress properties by Lactiplantibacillus plantarum SCS3 in streptozotocin-induced diabetic mice

Xiao Meng, Shukun Liu, Qiuyan Liu, Ying Zhang, Lin Jing, Xinyi Huang, Jiayi Sun and Lu Ye

CyTA - Journal of Food, 2022, 20, 297
DOI: 10.1080/19476337.2022.2136759

Lactiplantibacillus Plantarum as a Complementary Approach for Diabetes Treatment and Management

Akash Kumar, Vikram Kumar, Jhilam Pramanik, Sarvesh Rustagi, Bhupendra Prajapati, Ali Jebreen and Ranjana Pande

Curr Nutr Rep, 2025, 14
DOI: 10.1007/s13668-025-00664-x

A Single Strain of Lactobacillus (CGMCC 21661) Exhibits Stable Glucose- and Lipid-Lowering Effects by Regulating Gut Microbiota

Yuying Wang, Xiaozhong Wang, Xinzhu Xiao, Shufang Yu, Wennan Huang, Benqiang Rao and Fenglin Chen

Nutrients, 2023, 15, 670
DOI: 10.3390/nu15030670

The role of gut–islet axis in pancreatic islet function and glucose homeostasis

Qi Chen, Yuanyuan Gao, Fangyu Li and Li Yuan

Diabetes Obesity Metabolism, 2025, 27, 1676
DOI: 10.1111/dom.16225

Microbial network inference for longitudinal microbiome studies with LUPINE

Saritha Kodikara and Kim-Anh Lê Cao

Microbiome, 2025, 13
DOI: 10.1186/s40168-025-02041-w

Jiangtang Sanhao formula ameliorates skeletal muscle insulin resistance via regulating GLUT4 translocation in diabetic mice

Zimengwei Ye, Jinkun Ma, Yage Liu, Bingrui Xu, Xuan Dai, Min Fu, Tian Tian, Xin Sui, Fangfang Mo, Sihua Gao, Dandan Zhao and Dongwei Zhang

Front. Pharmacol., 2022, 13
DOI: 10.3389/fphar.2022.950535

Modulatory effects of Lactiplantibacillus plantarum on chronic metabolic diseases

Lei Tian, Ruixiang Zhao, Xinyi Xu, Zhiwei Zhou, Xiaofang Xu, Dongmei Luo, Zhiqiang Zhou, Yu Liu, Ariel Kushmaro, Robert S. Marks, András Dinnyés and Qun Sun

Food Science and Human Wellness, 2023, 12, 959
DOI: 10.1016/j.fshw.2022.10.018

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei and Yanhui Lu

iMetaOmics, 2025, 2
DOI: 10.1002/imo2.70020

Lacticaseibacillus rhamnosus SD11 improves gastrointestinal functions in multiple low doses of streptozotocin-induced type 1 diabetic mice

Jongdee Nopparat, Fittree Hayeeawaema, Saranya Peerakietkhajorn, Chittipong Tipbunjong, Nawiya Huipao, Rawee Teanpaisan and Pissared Khuituan

Food Bioscience, 2026, 76, 108290
DOI: 10.1016/j.fbio.2026.108290

Administration of Bifidobacterium animalis Subsp. lactis BLa80 and Lactobacillus acidophilus LA85 Improved Hyperglycemia and Modulated Gut Microbiota in Type 2 Diabetic Mice

Mingming Zhu, Lvzhu Yang, LuYao Li, Yuyuan Bai and Bin Zhao

Probiotics & Antimicro. Prot., 2026, 18, 822
DOI: 10.1007/s12602-025-10567-6

Probiotics and Curcumin Did Not Alter Low‐Dose Streptozotocin‐Induced Hyperglycemia and Oxidative Stress in a Rat Model

Cavdar Meliha, Yilmaz Muge and Ermiş Mustafa

Food Science & Nutrition, 2026, 14
DOI: 10.1002/fsn3.71624

Enhance the oral insulin delivery route using a modified chitosan-based formulation fabricated by microwave

Huda S. AlSalem, Nisreen M. Abdulsalam, Najla A. Khateeb, Mona S. Binkadem, Nahlah A. Alhadhrami, Abdalla M. Khedr, Rehab Abdelmonem, Kamel R. Shoueir and Eman Hassan Nadwa

International Journal of Biological Macromolecules, 2023, 247, 125779
DOI: 10.1016/j.ijbiomac.2023.125779

Health-Promoting and Functional Properties of Fermented Milk Beverages with Probiotic Bacteria in the Prevention of Civilization Diseases

Milena Alicja Stachelska, Piotr Karpiński and Bartosz Kruszewski

Nutrients, 2024, 17, 9
DOI: 10.3390/nu17010009

Empagliflozin ameliorates type 2 diabetes mellitus-related diabetic nephropathy via altering the gut microbiota

Le Deng, Yang Yang and Gaosi Xu

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2022, 1867, 159234
DOI: 10.1016/j.bbalip.2022.159234

Anti‐diabetic effect of banana peel dietary fibers on type 2 diabetic mellitus mice induced by streptozotocin and high‐sugar and high‐fat diet

Mengyang Wang, Fan Yang, Xiang Yan, Xinyu Chao, Wencheng Zhang, Chuanxun Yuan and Qingmei Zeng

Journal of Food Biochemistry, 2022, 46
DOI: 10.1111/jfbc.14275

Gut Microbiota: An Important Player in Type 2 Diabetes Mellitus

Zheng Zhou, Bao Sun, Dongsheng Yu and Chunsheng Zhu

Front. Cell. Infect. Microbiol., 2022, 12
DOI: 10.3389/fcimb.2022.834485

Metabolomics reveals the role of Lactobacillus plantarumSHY130 in hepatic metabolic regulation in a mouse model of type 2 diabetes

Guangqi Wang, Jiajia Song, Chen Wang, Xiaoyong Chen and Huayi Suo

J Sci Food Agric, 2023, 103, 6406
DOI: 10.1002/jsfa.12716

Study on the active ingredients and molecular mechanisms of Polygonatum sibiricum beverage in the intervention of type 2 diabetes mellitus based on UPLC-MS, network pharmacology and experimental validation

Meixian Ruan, Qianlong Ai, Guochao Cao, Fengxiao Ren, Zhouyao Zhang, Dekai Wang and Qiaojun Jia

Journal of Functional Foods, 2025, 127, 106762
DOI: 10.1016/j.jff.2025.106762

Ameliorative Effects of Lactobacillus plantarum HAC01 Lysate on 3T3-L1 Adipocyte Differentiation via AMPK Activation and MAPK Inhibition

Jong-Yeon Kim, Eun-Jung Park and Hae-Jeung Lee

IJMS, 2022, 23, 5901
DOI: 10.3390/ijms23115901

The Mechanisms of the Potential Probiotic Lactiplantibacillus plantarum against Cardiovascular Disease and the Recent Developments in its Fermented Foods

Zhe Wang, Juanjuan Wu, Zichen Tian, Yue Si, Hao Chen and Jing Gan

Foods, 2022, 11, 2549
DOI: 10.3390/foods11172549

Polygonatum sibiricum saponin-lactic acid bacteria combination attenuate hyperglycemia in T2DM mice by modulating amino acid metabolism

Jiayuan Luo, Mingjie Jia, Shuang Liang, Yangyang Chai, Yihong Bao and Shilong Jiang

Food Science and Human Wellness, 2025, 14, 9250097
DOI: 10.26599/FSHW.2024.9250097

Probiotic Mechanisms Affecting Glucose Homeostasis: A Scoping Review

Maša Pintarič and Tomaž Langerholc

Life, 2022, 12, 1187
DOI: 10.3390/life12081187

Novel Approaches in Glucose and Lipid Metabolism Disorder Therapy: Targeting the Gut Microbiota–Bile Acid Axis

Jin Jiang, Huange Zhang, Muhammad Hussain, Abdullah, Fengqin Feng, Rongfa Guan and Hao Zhong

Biology, 2025, 14, 802
DOI: 10.3390/biology14070802

Therapeutic Potential Targeting Gut Microbiota Modulation With Emphasis on Lactobacillus spp. in Common Metabolic Disorders: A Systematic Review

Md. Mizanur Rahaman, Phurpa Wangchuk, Subir Sarker and Carlos Viegas

Scientifica, 2025, 2025
DOI: 10.1155/sci5/3367875

Lactiplantibacillus plantarum SG053 and SG066 Enhance Nutritional Value of Soy Protein via Improved Essential Amino Acid Bioavailability

David Agus Setiawan Wibisono, Chiou-Yeong Saw, Der-Kai Lau, Wei-Jen Chen, Hui-Fang Chu, Cheng-Yen Liu and Chi-Fai Chau

Probiotics & Antimicro. Prot., 2026, 18, 1108
DOI: 10.1007/s12602-025-10602-6

Deciphering Microbial Carbohydrate Metabolism: Unveiling Mechanistic Insights Into Type 2 Diabetes

Navin Kumar, Swagata Sain, Bhawna Solanki and Jiong Yu

Advanced Gut & Microbiome Research, 2025, 2025
DOI: 10.1155/agm3/4395850

Pumpkin Soluble Dietary Fiber instead of Insoluble One Ameliorates Hyperglycemia via the Gut Microbiota–Gut–Liver Axis in db/db Mice

Fanghua Yan, Xinze Wang, Yue Du, Zhongna Zhao, Libing Shi, Tengzheng Cao, Yajun Shen, Lijun Sun and Xuebo Liu

J. Agric. Food Chem., 2025, 73, 1293
DOI: 10.1021/acs.jafc.4c08986

Supplementation with the Probiotic Strains Bifidobacterium longum and Lactiplantibacillus rhamnosus Alleviates Glucose Intolerance by Restoring the IL-22 Response and Pancreatic Beta Cell Dysfunction in Type 2 Diabetic Mice

Won Jun Kim, Ri Ryu, Eun-Hee Doo, Yukyung Choi, Kyunghwan Kim, Byoung Kook Kim, Heebal Kim, Myunghoo Kim and Chul Sung Huh

Probiotics & Antimicro. Prot., 2025, 17, 541
DOI: 10.1007/s12602-023-10156-5

Probiotics intervention for type 2 diabetes mellitus therapy: a review from proposed mechanisms to future prospects

Xue Li, Yongjun Xia, Xin Song, Zhiqiang Xiong, Lianzhong Ai and Guangqiang Wang

Critical Reviews in Food Science and Nutrition, 2025, 65, 4457
DOI: 10.1080/10408398.2024.2387765

Therapeutic Potential of Lactobacillus plantarum DS1 in Modulating Hypertension, Blood Sugar and Inflammation via ACE-2 Expression in Diabetic Rats

Dessy Abdullah, Nadia Purnama Dewi and Yudha Endra Pratama

Tropical Journal of Natural Product Research, 2025, 9
DOI: 10.26538/tjnpr/v9i9.57

Slowly Digestible Carbohydrate Diet Ameliorates Hyperglycemia and Hyperlipidemia in High-Fat Diet/Streptozocin-Induced Diabetic Mice

Yu-Zhong Chen, Jia Gu, Wei-Ting Chuang, Ya-Fang Du, Lin Zhang, Meng-Lan Lu, Jia-Ying Xu, Hao-Qiu Li, Yan Liu, Hao-Tian Feng, Yun-Hong Li and Li-Qiang Qin

Front. Nutr., 2022, 9
DOI: 10.3389/fnut.2022.854725

Heat-Killed Lactiplantibacillus plantarum LRCC5314 Mitigates the Effects of Stress-Related Type 2 Diabetes in Mice via Gut Microbiome Modulation

YoHan Nam, Seokmin Yoon, Jihye Baek, Jong-Hwa Kim, Miri Park, KwangWoo Hwang and Wonyong Kim

J. Microbiol. Biotechnol., 2022, 32, 324
DOI: 10.4014/jmb.2111.11008

Multi-strain probiotics attenuate carbohydrate-lipid metabolic dysregulation in type 2 diabetic rats via gut-liver axis modulation

Yecheng Gao, Yanfang Liu, Zelong Li, Liyi Lu, Yajuan Guo, Dun Su, Heping Zhang and Promi Das

mSystems, 2025, 10
DOI: 10.1128/msystems.00369-25

Transcriptome analysis reveals the mechanism underlying the tetracycline resistance of Lactiplantibacillus plantarum FZJTZ19M1 and FZJTZ29M8

Wenwei Lu, Qingqing Ma, Yue Xiao, Hongchao Wang, Jinlin Zhu, Wei Chen and Hao Zhang

Food Bioscience, 2023, 56, 103067
DOI: 10.1016/j.fbio.2023.103067

Effects of Bioconverted Guava Leaf (Psidium guajava L.) Extract on Skeletal Muscle Damage by Regulation of Ubiquitin–Proteasome System and Apoptosis in Type 2 Diabetic Mice

Heaji Lee, Bo-Gyu Jun, Su-Hyun Kim, Choong Hwan Lee and Yunsook Lim

IJMS, 2025, 26, 3877
DOI: 10.3390/ijms26083877

Lacticaseibacillus paracasei Glu-07: A Promising Probiotic Candidate for the Management of Type 2 Diabetes Mellitus

Wenyi Xu, Yinghua Guan, Liping Tian, Yu Fu, Yinghui Zhang, Yanhong Liu, Yanfei Hu, Bowen Zhao and Chongming Wu

Curr Microbiol, 2025, 82
DOI: 10.1007/s00284-025-04391-y

Supplementation with Probiotic Camel Milk Powder Improves Serum Glucose and Cholesterol as Well as the Related Cytokines in Patients with Type 2 Diabetes Mellitus

Yue Liu, Ming Zhang, Ran Wang, Shaoyang Ge and Bing Fang

Foods, 2025, 14, 3318
DOI: 10.3390/foods14193318

Impact of Lactobacillaceae supplementation on the multi-organ axis during MASLD

André A. Santos, Raquel Duarte, Madalena Duarte, Fabiola Arella, Vanda Marques, Stefan Roos and Cecília M.P. Rodrigues

Life Sciences, 2024, 354, 122948
DOI: 10.1016/j.lfs.2024.122948

The Modulatory Effects of Bacteroides thetaiotaomicron on Metabolic Parameters, Expression of Diabetes- and Inflammation-Related Genes and Gut Microbiota Composition in a Male Rat Model of Type 2 Diabetes Mellitus

Farzaneh Hasanian-Langroudi, Mehdi Hedayati, Asghar Ghasemi, Seyed Davar Siadat and Maryam Tohidi

Int J Endocrinol Metab, 2025, 23
DOI: 10.5812/ijem-168629

Aptamer Functionalized Liposomes Co-Loaded with Exenatide-4 and Coenzyme Q10 Ameliorate Type 2 Diabetes Mellitus by Improving Pancreatic β Cell Function

Shangying Xiao, Lei Rao, Canying Yan, Ling Nie, Leiqi Wang, Yingyin Zhao, Shihao Zhang, WeiMao Zhan, Dongyun Qin and Manjiao Zhuang

IJN, 2025, Volume 20, 3363
DOI: 10.2147/IJN.S510240

Antidiabetic and haematoprotective effects of an aqueous extract of Tremella fuciformis in streptozotocin-induced diabetic mice

Zahid Ahmad Wani, Asvene Kumar Sharma, Showkeen Muzamil , Rayees Ahmad Naik and Yaqoob lone

J. Drug Delivery Ther., 2026, 16, 106
DOI: 10.22270/jddt.v16i3.7611

Effects of Lactobacillus plantarum supplementation on glucose and lipid metabolism in type 2 diabetes mellitus and prediabetes: A systematic review and meta-analysis of randomized controlled trials

Hao Zhong, Lingmiao Wang, Fuhuai Jia, Yongqiu Yan, Feifei Xiong, Yunhong Li, Khemayanto Hidayat and Rongfa Guan

Clinical Nutrition ESPEN, 2024, 61, 377
DOI: 10.1016/j.clnesp.2024.04.009

Beneficial Effects of Probiotic Lactobacillus paraplantarum BGCG11 on Pancreatic and Duodenum Function in Diabetic Rats

Mirjana Mihailović, Svetlana Soković Bajić, Jelena Arambašić Jovanović, Emilija Brdarić, Svetlana Dinić, Nevena Grdović, Aleksandra Uskoković, Jovana Rajić, Marija Đorđević, Maja Tolinački, Nataša Golić, Milica Živković and Melita Vidaković

IJMS, 2024, 25, 7697
DOI: 10.3390/ijms25147697

Investigating the molecular mechanisms of Jiangu Decoction in treating type 2 diabetic osteoporosis

Yuchi Wei, Mingyue Wang, Zhanliang Jiang, Yuyan Jia, Yongmei Si, Zeyu Peng, Jie Yang, Ye Shi, Yongji Wu, Xiaolei Ding, Daian Pan, Daqing Zhao, Xiangyang Leng, Xiangyan Li and Haisi Dong

Journal of Ethnopharmacology, 2025, 341, 119346
DOI: 10.1016/j.jep.2025.119346

Communication in non-communicable diseases (NCDs) and role of immunomodulatory nutraceuticals in their management

Abhiram Kumar, Kalyani Sakhare, Dwaipayan Bhattacharya, Raktim Chattopadhyay, Purvish Parikh, Kumar P. Narayan and Anubhab Mukherjee

Front. Nutr., 2022, 9
DOI: 10.3389/fnut.2022.966152

Amelioration of Type 2 Diabetes Using Four Strains of Lactobacillus Probiotics: Effects on Gut Microbiota Reconstitution-Mediated Regulation of Glucose Homeostasis, Inflammation, and Oxidative Stress in Mice

Hainan Song, Hui Xue, Zeng Zhang, Jun Wang, Ao Li, Jiachao Zhang, Pengfei Luo, Meng Zhan, Xiaoli Zhou, Lihao Chen and Yajing Fang

J. Agric. Food Chem., 2023, 71, 20801
DOI: 10.1021/acs.jafc.3c04665

Vitamin D Alleviates Type 2 Diabetes Mellitus by Mitigating Oxidative Stress-Induced Pancreatic β-Cell Impairment

Jia Liu, Yuanjun Zhang, Derong Shi, Cuihuan He and Guanghao Xia

Exp Clin Endocrinol Diabetes, 2023, 131, 656
DOI: 10.1055/a-2191-9969

Mechanisms and key mediators of gut microbiota and type 2 diabetes mellitus: A comprehensive overview

Balapuwaduge Isuru Layan Madusanka Mendis, L. Sarvananda, Thilini N. Jayasinghe, Iyanthimala Harshini Rajapakse and Arosha Sampath Dissanayake

Medicine in Microecology, 2025, 26, 100144
DOI: 10.1016/j.medmic.2025.100144

Lactobacillus plantarum HAC01 Supplementation Improves Glycemic Control in Prediabetic Subjects: A Randomized, Double-Blind, Placebo-Controlled Trial

Mi-Ra Oh, Hui-Yeon Jang, Si-Yeon Lee, Su-Jin Jung, Soo-Wan Chae, Seung-Ok Lee and Byung-Hyun Park

Nutrients, 2021, 13, 2337
DOI: 10.3390/nu13072337

Gut microbiome sheds light on the development and treatment of abdominal aortic aneurysm

Xuebin Ling, Wei Jie, Xue Qin, Shuya Zhang, Kaijia Shi, Tianfa Li and Junli Guo

Front. Cardiovasc. Med., 2022, 9
DOI: 10.3389/fcvm.2022.1063683

Valorization of paneer waste whey through fermentation with Pediococcus pentosaceus NCDC 273 insights from intracellular metabolomics by GC-MS

Manish Singh Sansi, Daraksha Iram, Kamal Gandhi, Nishi Singh and Shiv Kumar Sood

Biocatalysis and Agricultural Biotechnology, 2026, 73, 104011
DOI: 10.1016/j.bcab.2026.104011

β-Glucan Alone or Combined with Lactobacillus acidophilus Positively Influences the Bacterial Diversity and Metabolites in the Colonic Microbiota of Type II Diabetic Patients

Jéssika Rodrigues Clementino, Louise Iara Gomes de Oliveira, Mateus Kawata Salgaço, Fellipe Lopes de Oliveira, Victoria Mesa, Josean Fechine Tavares, Ludmilla Silva-Pereira, Breno Vilas Boas Raimundo, Karen Cristina Oliveira, Alexandra Ivo Medeiros, Francyeli Araújo Silva, Katia Sivieri and Marciane Magnani

Probiotics & Antimicro. Prot., 2025, 17, 3728
DOI: 10.1007/s12602-025-10491-9

Reduction of Insulin Resistance by Momordica Charantia with Lactobacillus Acidophilus CBT-LA1 or Lactiplantibacillus Plantarum CBT-LP3 Improves Hepatosteatosis

Dong-Jin Kim, Ju Sung Lee, Seungwoo Kim, Sang Kyun Park, Yeo-Sang Yoon, Yougku Ryu and Myung Jun Chung

Microbiol. Biotechnol. Lett., 2024, 52, 275
DOI: 10.48022/mbl.2407.07008

Lactobacillus reuteri TISTR 2736 alleviates type 2 diabetes in rats via the hepatic IRS1/PI3K/AKT signaling pathway by mitigating oxidative stress and inflammatory mediators

Kamonthip Pakaew, Pennapa Chonpathompikunlert, Navinee Wongmanee, Worarat Rojanaverawong, Jaruwan Sitdhipol, Punnathorn Thaveethaptaikul, Natthawut Charoenphon and Wanthanee Hanchang

Eur J Nutr, 2025, 64
DOI: 10.1007/s00394-024-03529-1

Relationship between Intestinal Microbiota and Complications of Type 2 Diabetes

佳乐孙

ACM, 2023, 13, 1410
DOI: 10.12677/ACM.2023.132194

β-cell heterogeneity and molecular plasticity in type 2 diabetes: multi-omics perspectives and the role of gut microbiota

Evgeny Ruchko, Maria Chernysheva, Vasily Sokolov, Zakhar Starinnov, Marat Sabirov and Andrey Vasiliev

Front. Cell Dev. Biol., 2026, 13
DOI: 10.3389/fcell.2025.1698296

Decoding electroacupuncture’s efficacy: a comparative study on gut microbiota and metabolic profiles in C57 and 3xTg-AD mice

Chuyu Deng, Xingyu Cao, Xueying Wang, Chunzhi Tang and Zhenhua He

Front. Microbiol., 2026, 16
DOI: 10.3389/fmicb.2025.1687697

Updated Insights into Probiotic Interventions for Metabolic Syndrome: Mechanisms and Evidence

Lili Chen, Lvbo Tian, Yuqi Zhang, Ying Shi, Wenyi Yuan, Yue Zou, Qin Zhang, Moutong Chen and Peibin Zeng

Probiotics & Antimicro. Prot., 2026, 18, 1527
DOI: 10.1007/s12602-025-10554-x

Association of the short-chain fatty acid levels and dietary quality with type 2 diabetes: a case–control study based on Henan Rural Cohort

Jia Li, Yuqian Li, Shuhua Zhang, Chongjian Wang, Zhenxing Mao, Wenqian Huo, Tianyu Yang, Yan Li, Wenguo Xing and Linlin Li

Br J Nutr, 2024, 1
DOI: 10.1017/S0007114524000400

P2X7R and P2X4R expression of mice submandibular gland in high-fat diet/streptozotocin-induced type 2 diabetes

Jiratchaya Srisutha, Ippei Watari, Masato Akakura, Minami Watanabe, Chidsanu Changsiripun and Takashi Ono

Sci Rep, 2024, 14
DOI: 10.1038/s41598-024-60519-3

Characterization and temporal dynamics of the intra- and extracellular environments of Lactiplantibacillus plantarum using multi-platform metabolomics

Su-Hyun Kim, Digar Singh, Su Young Son, Sunmin Lee, Dong Ho Suh, Na-Rae Lee, Gun-Seok Park, Jihee Kang and Choong Hwan Lee

LWT, 2023, 175, 114376
DOI: 10.1016/j.lwt.2022.114376

Gut-Microbial Metabolites, Probiotics and Their Roles in Type 2 Diabetes

Lixiang Zhai, Jiayan Wu, Yan Y. Lam, Hiu Yee Kwan, Zhao-Xiang Bian and Hoi Leong Xavier Wong

IJMS, 2021, 22, 12846
DOI: 10.3390/ijms222312846

Effects of home-based exercise training on gut microbiota and possible relations with cognitive function and metabolic health in postmenopausal women with type 2 diabetes mellitus: a randomized control trial

A. Vahed, M. Molanouri Shamsi, S.D. Siadat, M. Behmanesh, R. Negaresh, S. Agh-Mohammadi and M. Ebrahimi

Diabetes Research and Clinical Practice, 2025, 229, 112908
DOI: 10.1016/j.diabres.2025.112908

Gut microbiota and its metabolites regulate insulin resistance: traditional Chinese medicine insights for T2DM

Jing Liu, Fuxing Li, Le Yang, Shengping Luo and Yihui Deng

Front. Microbiol., 2025, 16
DOI: 10.3389/fmicb.2025.1554189

Lacticaseibacillus rhamnosus Hao9 exerts antidiabetic effects by regulating gut microbiome, glucagon metabolism, and insulin levels in type 2 diabetic mice

Mei Han, Wenyan Liao, Yao Dong, Chen Bai and Zhonghui Gai

Front. Nutr., 2023, 9
DOI: 10.3389/fnut.2022.1081778

Selenium-enriched Lactiplantibacillus plantarum alleviates alkalinity stress-induced selective hepatic insulin resistance in common carp

Xinghua Che, Xinchi Shang, WeiXu, Meiqi Xing, Haiju Wei, Wang Li, Zhengwei Li, Xiaohua Teng and Longwu Geng

International Journal of Biological Macromolecules, 2025, 305, 141204
DOI: 10.1016/j.ijbiomac.2025.141204

Anti-diabetic effects of probiotic and postbiotic Lactiplantibacillus plantarum R6-3 from Sayram ketteki in T2DM mice via modulating gut microbiota and intestinal barrier

Yajing Liu, Chen Li, Bingyong Mao, Na Zhang, Chenwei Li, Fenghe Qin, Shumei Cheng, Qinghai Sheng, Miaoshu Wang, Dongyao Li and Hongtao Tian

Food Bioscience, 2025, 74, 108024
DOI: 10.1016/j.fbio.2025.108024