Constant-potential environment for activating and synchronizing cardiomyocyte colonies with on-chip ion-depleting perm-selective membranes

Vivek Yadav, Nicholas Chong, Bradley Ellis, Xiang Ren, Satyajyoti Senapati, Hsueh-Chia Chang and Pinar Zorlutuna

Lab Chip, 2020, 20, 4273
DOI: 10.1039/D0LC00809E

Heart-on-a-chip systems with tissue-specific functionalities for physiological, pathological, and pharmacological studies

Bingsong Gu, Kang Han, Hanbo Cao, Xinxin Huang, Xiao Li, Mao Mao, Hui Zhu, Hu Cai, Dichen Li and Jiankang He

Materials Today Bio, 2024, 24, 100914
DOI: 10.1016/j.mtbio.2023.100914

Sensors in heart-on-a-chip: A review on recent progress

Kyoung Won Cho, Wang Hee Lee, Byung-Soo Kim and Dae-Hyeong Kim

Talanta, 2020, 219, 121269
DOI: 10.1016/j.talanta.2020.121269

Generation and Culture of Cardiac Microtissues in a Microfluidic Chip with a Reversible Open Top Enables Electrical Pacing, Dynamic Drug Dosing and Endothelial Cell Co‐Culture

Aisen Vivas, Camilo IJspeert, Jesper Yue Pan, Kim Vermeul, Albert van den Berg, Robert Passier, Stephan Sylvest Keller and Andries D. van der Meer

Adv Materials Technologies, 2022, 7
DOI: 10.1002/admt.202101355

Engineering Cardiac Tissue for Advanced Heart‐On‐A‐Chip Platforms

Xinyi Chen, Sitian Liu, Mingying Han, Meng Long, Ting Li, Lanlan Hu, Ling Wang, Wenhua Huang and Yaobin Wu

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202301338

Architecture design and advanced manufacturing of heart-on-a-chip: scaffolds, stimulation and sensors

Feng Xu, Hang Jin, Lingling Liu, Yuanyuan Yang, Jianzheng Cen, Yaobin Wu, Songyue Chen and Daoheng Sun

Microsyst Nanoeng, 2024, 10
DOI: 10.1038/s41378-024-00692-7

Heart-on-Chip for Combined Cellular Dynamics Measurements and Computational Modeling Towards Clinical Applications

Jiyoon Park, Ziqian Wu, Paul R. Steiner, Bo Zhu and John X. J. Zhang

Ann Biomed Eng, 2022, 50, 111
DOI: 10.1007/s10439-022-02902-7

Printed Electronic Devices and Systems for Interfacing with Single Cells up to Organoids

Mahsa K. Saghafi, Srivatsan K. Vasantham, Navid Hussain, George Mathew, Federico Colombo, Barbara Schamberger, Eric Pohl, Gabriel Cadilha Marques, Ben Breitung, Motomu Tanaka, Martin Bastmeyer, Christine Selhuber‐Unkel, Ute Schepers, Michael Hirtz and Jasmin Aghassi‐Hagmann

Adv Funct Materials, 2024, 34
DOI: 10.1002/adfm.202308613

Microfabrication of polydimethylsiloxane–parylene hybrid microelectrode array integrated into a multi-organ-on-a-chip

Dongxiao Zhang, Jiandong Yang, Yoshikazu Hirai, Ken-ichiro Kamei, Osamu Tabata and Toshiyuki Tsuchiya

Jpn. J. Appl. Phys., 2023, 62, 017002
DOI: 10.35848/1347-4065/aca265

Cardiac Cell Patterning on Customized Microelectrode Arrays for Electrophysiological Recordings

Jiaying Ji, Xiang Ren and Pinar Zorlutuna

Micromachines, 2021, 12, 1351
DOI: 10.3390/mi12111351

Essential Role of Anisotropy in Bioengineered Cardiac Tissue Models

Aditi Jain, Saswat Choudhury, Nagalingam R. Sundaresan and Kaushik Chatterjee

Advanced Biology, 2024, 8
DOI: 10.1002/adbi.202300197

Flexible beam-based microelectrode arrays integrated with oriented nanofiber scaffolds for electrophysiological monitoring of cardiac tissue

Wangzihan Zhang, Mingcheng Xue, Hang Jin, Jianhui Yang, Huiquan Wu, Bin Qiu, Yuqing Jiang, Feng Xu, Bin Lin, Weiwei Kong, Jianzheng Cen, Songyue Chen and Daoheng Sun

Acta Biomaterialia, 2025, 201, 309
DOI: 10.1016/j.actbio.2025.06.005

Intercellular Communication in the Heart: Therapeutic Opportunities for Cardiac Ischemia

Tania Martins-Marques, Derek J. Hausenloy, Joost P.G. Sluijter, Luc Leybaert and Henrique Girao

Trends in Molecular Medicine, 2021, 27, 248
DOI: 10.1016/j.molmed.2020.10.002

Step-by-step fabrication of heart-on-chip systems as models for cardiac disease modeling and drug screening

Sara Deir, Yasaman Mozhdehbakhsh Mofrad, Shohreh Mashayekhan, Amir Shamloo and Amirreza Mansoori-Kermani

Talanta, 2024, 266, 124901
DOI: 10.1016/j.talanta.2023.124901

Organotypic and Microphysiological Human Tissue Models for Drug Discovery and Development—Current State-of-the-Art and Future Perspectives

Sonia Youhanna, Aurino M. Kemas, Lena Preiss, Yitian Zhou, Joanne X. Shen, Selgin D. Cakal, Francesco S. Paqualini, Sravan K. Goparaju, Reza Zandi Shafagh, Johan Ulrik Lind, Carl M. Sellgren and Volker M. Lauschke

Pharmacological Reviews, 2022, 74, 141
DOI: 10.1124/pharmrev.120.000238

Advancing organ-on-chip systems: the role of microfluidics in neuro-cardiac research

Maria João Ferreira, Sarah Colombani, Albin Bernardin, Alain Lacampagne, Jean-Luc Pasquié, Pedro F. Costa, Benoit Charlot and Albano C. Meli

Current Research in Pharmacology and Drug Discovery, 2025, 9, 100227
DOI: 10.1016/j.crphar.2025.100227

Recent Advances in Cardiac Tissue Engineering for the Management of Myocardium Infarction

Vineeta Sharma, Sanat Kumar Dash, Kavitha Govarthanan, Rekha Gahtori, Nidhi Negi, Mahmood Barani, Richa Tomar, Sudip Chakraborty, Santosh Mathapati, Dillip Kumar Bishi, Poonam Negi, Kamal Dua, Sachin Kumar Singh, Rohit Gundamaraju, Abhijit Dey, Janne Ruokolainen, Vijay Kumar Thakur, Kavindra Kumar Kesari, Niraj Kumar Jha, Piyush Kumar Gupta and Shreesh Ojha

Cells, 2021, 10, 2538
DOI: 10.3390/cells10102538

Roadblocks confronting widespread dissemination and deployment of Organs on Chips

Charles G. Alver, Emma Drabbe, Matthew Ishahak and Ashutosh Agarwal

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-48864-3

Biomimetic microsystems for cardiovascular studies

Shelby C. Inbody, Bridgett E. Sinquefield, Joshua P. Lewis and Renita E. Horton

American Journal of Physiology-Cell Physiology, 2021, 320, C850
DOI: 10.1152/ajpcell.00026.2020

Effects of fibrillin mutations on the behavior of heart muscle cells in Marfan syndrome

Jeffrey Aalders, Laurens Léger, Louis Van der Meeren, Natasja Van den Vreken, Andre G. Skirtach, Sanjay Sinha, Julie De Backer and Jolanda van Hengel

Sci Rep, 2020, 10
DOI: 10.1038/s41598-020-73802-w